Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0RI4S
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| Former ID |
DNC007576
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| Drug Name |
2-benzyl-2H-pyrazolo[3,4-c]quinolin-4(5H)-one
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| Synonyms |
CHEMBL242205; 2-benzyl-2H-pyrazolo[3,4-c]quinolin-4(5H)-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H13N3O
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| Canonical SMILES |
C1=CC=C(C=C1)CN2C=C3C4=CC=CC=C4NC(=O)C3=N2
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| InChI |
1S/C17H13N3O/c21-17-16-14(13-8-4-5-9-15(13)18-17)11-20(19-16)10-12-6-2-1-3-7-12/h1-9,11H,10H2,(H,18,21)
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| InChIKey |
XJRYZVBNFXKWFF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A3 receptor (ADORA3) | Target Info | Inhibitor | [1] |
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluati... J Med Chem. 2007 Aug 23;50(17):4061-74. | |||
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