Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S0YV
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| Drug Name |
modified HA14-1 compounds (cancer)
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| Synonyms |
Bcl-2 inhibitor (cancer), GL Pharmaceuticals; HA14-1, GL Pharmaceuticals
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The small-molecule Bcl-2 inhibitor HA14-1 interacts synergistically with flavopiridol to induce mitochondrial injury and apoptosis in human myeloma cells through a free radical-dependent and Jun NH2-terminal kinase-dependent mechanism. Mol Cancer Ther. 2004 Dec;3(12):1513-24. | |||
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