Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0SQ1T
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| Former ID |
DNC010937
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| Drug Name |
2,5-dideoxy-2,5-imino-D-altritol
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| Synonyms |
CHEMBL469844; 172823-15-3; CHEMBL10437; SCHEMBL2435520; CTK0A7803; DTXSID40437432; ZINC5766623; 2,5-Imino-2,5-dideoxy-D-altritol; BDBM50241865; BDBM50099008; (2R,3S,4S)-2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol; 2,5-Pyrrolidinedimethanol, 3,4-dihydroxy-, (2R,3R,4S,5R)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C6H13NO4
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| Canonical SMILES |
C(C1C(C(C(N1)CO)O)O)O
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| InChI |
1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1
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| InChIKey |
PFYHYHZGDNWFIF-KAZBKCHUSA-N
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| CAS Number |
CAS 172823-15-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Alpha-galactosidase A (GLA) | Target Info | Inhibitor | [1] |
| Lactase-phlorizin hydrolase (LCT) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Galactose metabolism | |||
| Metabolic pathways | ||||
| Carbohydrate digestion and absorption | ||||
| Glycerolipid metabolism | ||||
| Sphingolipid metabolism | ||||
| Glycosphingolipid biosynthesis - globo series | ||||
| Lysosome | ||||
| Pathwhiz Pathway | Lactose Degradation | |||
| Galactose Metabolism | ||||
| Sphingolipid Metabolism | ||||
| Reactome | Glycosphingolipid metabolism | |||
| WikiPathways | Metabolism of carbohydrates | |||
| Sphingolipid metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease. Bioorg Med Chem. 2010 Jun 1;18(11):3790-4. | |||
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