Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T5IN
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| Former ID |
DIB003866
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| Drug Name |
PX-867
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| Synonyms |
PI-3-K inhibitor (cardiovascular disease), Oncothyreon; Phosphatidylinositol-3-kinase inhibitor (cardiovascular disease), Oncothyreon
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| Drug Type |
Small molecular drug
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| Indication | Cardiovascular disease [ICD-11: BA00-BE2Z; ICD-10: I00-I99] | Terminated | [1] | |
| Company |
Oncothyreon Inc
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| Structure |
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Download2D MOL |
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| Formula |
C27H33NO8
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| Canonical SMILES |
CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C(=CN5CCCC5)C4=C(C3=O)O)COC)C)C
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| InChI |
1S/C27H33NO8/c1-14(29)35-17-11-26(2)16(7-8-18(26)30)20-22(17)27(3)19(13-34-4)36-25(33)15(12-28-9-5-6-10-28)21(27)24(32)23(20)31/h12,16-17,19,32H,5-11,13H2,1-4H3/b15-12-/t16-,17+,19+,26-,27-/m0/s1
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| InChIKey |
JUSZLIOETSSZJM-WQVKNQJISA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028453) | |||
| REF 2 | Pharmacologic profiling of phosphoinositide 3-kinase inhibitors as mitigators of ionizing radiation-induced cell death. J Pharmacol Exp Ther. 2013 Dec;347(3):669-80. | |||
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