Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T8AJ
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| Former ID |
DNC009659
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| Drug Name |
N-(biphenyl-3-yl)-6-(sulfamoylamino)hexanamide
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| Synonyms |
CHEMBL475301; N-(biphenyl-3-yl)-6-(sulfamoylamino)hexanamide; SCHEMBL5327672
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H23N3O3S
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CC(=CC=C2)NC(=O)CCCCCNS(=O)(=O)N
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| InChI |
1S/C18H23N3O3S/c19-25(23,24)20-13-6-2-5-12-18(22)21-17-11-7-10-16(14-17)15-8-3-1-4-9-15/h1,3-4,7-11,14,20H,2,5-6,12-13H2,(H,21,22)(H2,19,23,24)
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| InChIKey |
XZBFBJMQHOJIMB-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histone deacetylase 6 (HDAC6) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Alcoholism | |||
| Viral carcinogenesis | ||||
| Pathway Interaction Database | Signaling events mediated by HDAC Class II | |||
| Signaling events mediated by HDAC Class I | ||||
| Reactome | NOTCH1 Intracellular Domain Regulates Transcription | |||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | ||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | ||||
| Assembly of the primary cilium | ||||
| WikiPathways | Ectoderm Differentiation | |||
| Neural Crest Differentiation | ||||
| Cell Cycle | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Sulfamides as novel histone deacetylase inhibitors. Bioorg Med Chem Lett. 2009 Jan 15;19(2):336-40. | |||
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