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| Target and Pathway |
Top |
| Target(s) |
Metabotropic glutamate receptor 1 (mGluR1) |
Target Info
|
Modulator (allosteric modulator) |
[1] |
| References |
Top |
| REF 1 |
Rapid hit to lead evaluation of pyrazolo[3,4-d]pyrimidin-4-one as selective and orally bioavailable mGluR1 antagonists. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4303-7.
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| REF 2 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6342).
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