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| Target and Pathway |
Top |
| Target(s) |
Dopamine D3 receptor (D3R) |
Target Info
|
Inhibitor |
[2] |
| Dopamine D4 receptor (D4R) |
Target Info
|
Inhibitor |
[2] |
| Sodium channel unspecific (NaC) |
Target Info
|
Inhibitor |
[3] |
| Voltage-gated sodium channel alpha Nav1.3 (SCN3A) |
Target Info
|
Inhibitor |
[3] |
| References |
Top |
| REF 1 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3302).
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| REF 2 |
5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole: a potent, selective antagonist at human cloned dopamine D4 receptors. J Med Chem. 1996 May 10;39(10):1943-5.
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| REF 3 |
1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1, 3-dihydroimidazol-2-one: a selective high-affinity antagonist for the human dopamine D(4) rece... J Med Chem. 1999 Jul 15;42(14):2706-15.
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