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| Target and Pathway |
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| Target(s) |
PI3-kinase gamma (PIK3CG) |
Target Info
|
Modulator |
[2] |
| Serine/threonine-protein kinase mTOR (mTOR) |
Target Info
|
Modulator |
[2] |
| References |
Top |
| REF 1 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7951).
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| REF 2 |
Simultaneous targeting of PI3K and mTOR with NVP-BGT226 is highly effective in multiple myeloma. Anticancer Drugs. 2012 Jan;23(1):131-8.
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