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Target and Pathway |
Top |
Target(s) |
C-C chemokine receptor type 2 (CCR2) |
Target Info
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Antagonist |
[3] |
C-C chemokine receptor type 5 (CCR5) |
Target Info
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Modulator |
[2] |
References |
Top |
REF 1 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 801).
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REF 2 |
The dual CCR5 and CCR2 inhibitor cenicriviroc does not redistribute HIV into extracellular space: implications for plasma viral load and intracellular DNA decline. J Antimicrob Chemother. 2015 Mar;70(3):750-6.
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REF 3 |
Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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