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| Target and Pathway |
Top |
| Target(s) |
Fms-like tyrosine kinase 3 (FLT-3) |
Target Info
|
Inhibitor |
[2] |
| Platelet-derived growth factor receptor alpha (PDGFRA) |
Target Info
|
Inhibitor |
[2] |
| Platelet-derived growth factor receptor beta (PDGFRB) |
Target Info
|
Inhibitor |
[2] |
| Tyrosine-protein kinase Kit (KIT) |
Target Info
|
Inhibitor |
[2] |
| Vascular endothelial growth factor receptor 1 (FLT-1) |
Target Info
|
Inhibitor |
[2] |
| Vascular endothelial growth factor receptor 2 (KDR) |
Target Info
|
Inhibitor |
[2] |
| Vascular endothelial growth factor receptor 3 (FLT-4) |
Target Info
|
Inhibitor |
[2] |
| References |
Top |
| REF 1 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7886).
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| REF 2 |
Metabolism and bioactivation of famitinib, a novel inhibitor of receptor tyrosine kinase, in cancer patients. Br J Pharmacol. 2013 Apr;168(7):1687-706.
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