Target's General Information
Target ID T30635
Target Name C-X-C motif chemokine 10 (CXCL10)
Synonyms Small-inducible cytokine B10; SCYB10; IP-10; INP10; Gamma-IP10; 10 kDa interferon gamma-induced protein
Target Type Clinical trial
Gene Name CXCL10
Biochemical Class Cytokine: CXC chemokine
UniProt ID CXL10_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Ulcerative colitis
Example drug Anti-IP10 Phase 2 [1], [2], [3]
Tissue Colon mucosal tissue
Level of differential expression between the patients in the disease section of the tissue section of the tissue adjacent to the disease section Fold-change: 0.65
Z-score: 0.27
P-value: 6.07E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 ClinicalTrials.gov (NCT01466374) Induction and Maintenance Study of BMS-936557 in Patients With Moderate to Severely Active Crohn's Disease. U.S. National Institutes of Health.
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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