Target expression details
| Target's General Information | |||||
|---|---|---|---|---|---|
| Target ID | T39610 | ||||
| Target Name | Calmodulin (CALM) | ||||
| Synonyms | CaM; CALM2 | ||||
| Target Type | Successful | ||||
| Gene Name | CALM | ||||
| Biochemical Class | Calmodulin-dependent secretion | ||||
| UniProt ID | CALM_HUMAN | ||||
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
| Disease | Schizophrenia | ||||
| Example drug | Trifluoperazine | Approved | [1], [2], [3] | ||
| Tissue | Pre-frontal cortex | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.09 Z-score: 0.15 P-value: 6.44E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Disease | Schizophrenia | ||||
| Example drug | Trifluoperazine | Approved | [1], [2], [3] | ||
| Tissue | Superior temporal cortex | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: -3.28E-04 Z-score: -1.09E-03 P-value: 5.89E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Target's Expression Profile across Various Tissues of Healthy Individual | |||||
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| References | |||||
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | ||||
| REF 3 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. | ||||
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