Target expression details
| Target's General Information | |||||
|---|---|---|---|---|---|
| Target ID | T86273 | ||||
| Target Name | G-protein coupled bile acid receptor 1 (GPBAR1) | ||||
| Synonyms | hGPCR19; hBG37; TGR5; Membrane-type receptor for bile acids; M-BAR; G-protein coupled receptor GPCR19; BG37 | ||||
| Target Type | Clinical trial | ||||
| Gene Name | GPBAR1 | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | GPBAR_HUMAN | ||||
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
| Disease | Type 2 diabetes | ||||
| Example drug | Sodium taurocholate | Phase 1/2 | [1] | ||
| Tissue | Liver tissue | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.02 Z-score: 0.09 P-value: 4.60E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| References | |||||
| REF 1 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. | ||||
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