Target's General Information
Target ID T89515
Target Name Polypeptide deformylase (PDF)
Synonyms PDF
Target Type Successful
Gene Name PDF
Biochemical Class CH-NH donor oxidoreductase
UniProt ID DYR_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Acute myelocytic leukemia
Example drug Aminopterin Withdrawn from market [1], [2]
Tissue Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.54
Z-score: -0.86
P-value: 8.87E-16
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Disease Rheumatoid arthritis
Tissue Synovial tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.38
Z-score: 1.46
P-value: 1.08E-02
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Disease Bladder cancer
Tissue Bladder tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.97
Z-score: 3.88
P-value: 5.11E-06
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
References
REF 1 Drug information of Aminopterin, Health Canada, 2007.
REF 2 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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