miRNA General Information
miRNA Mature ID hsa-miR-23b-5p
miRNA Stemloop AC MI0000439
miRNA Stemloop ID hsa-mir-23b
Sequence uggguuccuggcaugcugauuu
TTD Target(s) Regulated by This miRNA Mothers against decapentaplegic homolog 3 (SMAD3) Successful Target Target Info [1]
Transforming growth factor beta 2 (TGFB2) Clinical trial Target Target Info [2]
TGF-beta receptor type II (TGFBR2) Clinical trial Target Target Info [2]
Protein(s) Regulated by This miRNA Proline dehydrogenase 1, mitochondrial Regulated Protein [3]
References
REF 1 MicroRNA-23b Inhibits the Proliferation and Migration of Heat-Denatured Fibroblasts by Targeting Smad3. PLoS One. 2015 Jul 8;10(7):e0131867.
REF 2 Umbilical Cord-Derived Mesenchymal Stem Cell-Derived Exosomal MicroRNAs Suppress Myofibroblast Differentiation by Inhibiting the Transforming Growth Factor-/SMAD2 Pathway During Wound Healing. Stem Cells Transl Med. 2016 Oct;5(10):1425-1439.
REF 3 miR-23b targets proline oxidase, a novel tumor suppressor protein in renal cancer.Oncogene. 2010 Sep 2;29(35):4914-24.

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