miRNA General Information
miRNA Mature ID hsa-miR-339-5p
miRNA Stemloop AC MI0000815
miRNA Stemloop ID hsa-mir-339
Sequence ucccuguccuccaggagcucacg
TTD Target(s) Regulated by This miRNA Ubiquitin-protein ligase E3 Mdm2 (MDM2) Clinical trial Target Target Info [1]
Beta-secretase 1 (BACE1) Clinical trial Target Target Info [2]
Protein tyrosine phosphatase IVA 1 (PRL-1) Literature-reported Target Target Info [3]
Protein(s) Regulated by This miRNA B-cell lymphoma 6 protein Regulated Protein [4]
RNA-binding protein Nova-1 Regulated Protein [5]
References
REF 1 miR-339-5p regulates the p53 tumor-suppressor pathway by targeting MDM2. Oncogene. 2015 Apr 9;34(15):1908-18.
REF 2 MicroRNA-339-5p down-regulates protein expression of -site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects. J Biol Chem. 2014 Feb 21;289(8):5184-98.
REF 3 MiR-339-5p regulates the growth, colony formation and metastasis of colorectal cancer cells by targeting PRL-1. PLoS One. 2013 May 16;8(5):e63142.
REF 4 MiR-339-5p inhibits breast cancer cell migration and invasion in vitro and may be a potential biomarker for breast cancer prognosis.BMC Cancer. 2010 Oct 9;10:542.
REF 5 MicroRNA-339, an epigenetic modulating target is involved in human gastric carcinogenesis through targeting NOVA1.FEBS Lett. 2015 Oct 7;589(20 Pt B):3205-11.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.