miRNA General Information
miRNA Mature ID hsa-miR-483-3p
miRNA Stemloop AC MI0002467
miRNA Stemloop ID hsa-mir-483
Sequence ucacuccucuccucccgucuu
TTD Target(s) Regulated by This miRNA Cyclin-dependent kinase 4 (CDK4) Successful Target Target Info [1]
Connective tissue growth factor (CTGF) Clinical trial Target Target Info [2]
Insulin-like growth factor-I (IGF1) Clinical trial Target Target Info [3]
Bcl-2-binding component 3 (BBC3) Literature-reported Target Target Info [4]
Protein(s) Regulated by This miRNA Etoposide-induced protein 2.4 homolog Regulated Protein [5]
Mothers against decapentaplegic homolog 4 Regulated Protein [6]
Partitioning defective 3 homolog Regulated Protein [7]
Ras-specific guanine nucleotide-releasing factor 1 Regulated Protein [1]
Rho GTPase-activating protein 7 Regulated Protein [9]
Serum response factor Regulated Protein [10]
References
REF 1 CDC25A targeting by miR-483-3p decreases CCND-CDK4/6 assembly and contributes to cell cycle arrest. Cell Death Differ. 2013 Jun;20(6):800-11.
REF 2 miR-483 Targeting of CTGF Suppresses Endothelial-to-Mesenchymal Transition: Therapeutic Implications in Kawasaki Disease. Circ Res. 2017 Jan 20;120(2):354-365.
REF 3 IGF-1 promotes the development and cytotoxic activity of human NK cells. Nat Commun. 2013;4:1479.
REF 4 Oncogenic role of miR-483-3p at the IGF2/483 locus. Cancer Res. 2010 Apr 15;70(8):3140-9.
REF 5 miR-483-3p plays an oncogenic role in esophageal squamous cell carcinoma by targeting tumor suppressor EI24.Cell Biol Int. 2016 Apr;40(4):448-55.
REF 6 MicroRNA 483-3p suppresses the expression of DPC4/Smad4 in pancreatic cancer.FEBS Lett. 2011 Jan 3;585(1):207-13.
REF 7 Identification of specific miRNAs targeting proteins of the apical junctional complex that simulate the probiotic effect of E. coli Nissle 1917 on T84 epithelial cells.Int J Biochem Cell Biol. 2012 Feb;44(2):341-9.
REF 8 CDC25A targeting by miR-483-3p decreases CCND-CDK4/6 assembly and contributes to cell cycle arrest. Cell Death Differ. 2013 Jun;20(6):800-11.
REF 9 IGF2-derived miR-483 mediated oncofunction by suppressing DLC-1 and associated with colorectal cancer.Oncotarget. 2016 Jul 26;7(30):48456-48466.
REF 10 Upregulation of miR-483-3p contributes to endothelial progenitor cells dysfunction in deep vein thrombosis patients via SRF.J Transl Med. 2016 Jan 22;14:23.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.