Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | Caspase-10 (CASP10) | Patented-recorded | Target Info | ||
| UniProt ID | CASPA_HUMAN | ||||
| Gene Name | CASP10 | ||||
| Gene ID | 843 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Clinical trial Target(s) | Apoptosis mediating surface antigen FAS (FAS) | Target Info | PPI Info | [1] | |
| X-linked inhibitor of apoptosis protein (XIAP) | Target Info | PPI Info | [2] | ||
| Interacting Patented-recorded Target(s) | Caspase-8 (CASP8) | Target Info | PPI Info | [3] | |
| Interacting Literature-reported Target(s) | CASP8-FADD-like regulator (CFLAR) | Target Info | PPI Info | [4] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling. J Biol Chem. 1997 Mar 7;272(10):6578-83. | ||||
| REF 2 | Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6170-5. | ||||
| REF 3 | Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria. J Biol Chem. 2002 Apr 19;277(16):13430-7. | ||||
| REF 4 | CASH, a novel caspase homologue with death effector domains. J Biol Chem. 1997 Aug 8;272(32):19641-4. | ||||
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