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| Protein General Information (TTD Target) |
Top |
| Full Name |
BDNF/NT-3 growth factors receptor (TrkB)
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Successful
|
Target Info
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| UniProt ID |
NTRK2_HUMAN
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| Gene Name |
NTRK2
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| Gene ID |
4915
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Epidermal growth factor receptor (EGFR) |
Target Info
|
PPI Info
|
[1] |
| Interacting Clinical trial Target(s) |
Protein-tyrosine phosphatase 1B (PTP1B) |
Target Info
|
PPI Info
|
[2] |
| Interacting Literature-reported Target(s) |
Neurotrophin-4 (NTF4) |
Target Info
|
PPI Info
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[3] |
| References |
Top |
| REF 1 |
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods. 2014 May;11(5):585-92.
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| REF 2 |
The SPOT technique as a tool for studying protein tyrosine phosphatase substrate specificities. Protein Sci. 2002 Oct;11(10):2326-34.
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| REF 3 |
Specificity in Trk receptor:neurotrophin interactions: the crystal structure of TrkB-d5 in complex with neurotrophin-4/5. Structure. 2001 Dec;9(12):1191-9.
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