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Protein General Information |
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Full Name |
TNFAIP3-interacting protein 2 (TNIP2)
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UniProt ID |
TNIP2_HUMAN
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Gene Name |
TNIP2
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Gene ID |
79155
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Interacting TTD Target Information |
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Interacting Clinical trial Target(s) |
DNA-binding factor KBF1 (p105) |
Target Info
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PPI Info
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[1] |
Interacting Patented-recorded Target(s) |
Polyubiquitin-C (UBC) |
Target Info
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PPI Info
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[2] |
Interacting Literature-reported Target(s) |
Zinc finger protein A20 (TNFAIP3) |
Target Info
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PPI Info
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[3] |
References |
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REF 1 |
ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability. Mol Cell Biol. 2004 Jun;24(12):5235-48.
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REF 2 |
Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins. Oncogene. 2008 Jun 12;27(26):3739-45.
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REF 3 |
Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2. J Biol Chem. 2001 Aug 10;276(32):30216-23.
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