Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T09826 | Target Info | |||
| Target Name | DNA topoisomerase I (TOP1) | ||||
| Synonyms |
DNA topoisomerase I
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|
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| Target Type | Successful Target | ||||
| Gene Name | TOP1 | ||||
| Biochemical Class | Topoisomerase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 104 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Ribavirin
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|
Approved | Compound Info | ||
| Synonyms |
ribavirin; 36791-04-5; Tribavirin; Rebetol; Virazole; Ribavirine; Copegus; Vilona; Ribamide; Ribasphere; Ribamidil; Viramid; Ribamidyl; Ribavirinum; Ribavirina; Rebetron; Varazid; RTCA; Ribavirin Capsules; Ribavirinum [INN-Latin]; Ribavirine [INN-French]; Ribavirina [INN-Spanish]; ICN-1229; Rebretron; Virazid; Ribav; 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide; DRG-0028; 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide; UNII-49717AWG6K; Ribavirin (Copegus); Copegus; Cotronak; RBV; RTC; Ravanex; Ribacine; Ribovirin; Viramide; Virazide; R 9644; SCH 18908; C-Virin; Copegus (TN); Drug: Ribavirin; KS-1104; R-964; RG-964; Rebetol (TN); Ribasphere (TN); Ribavirin [USAN:INN]; Vilona (TN); Virazole (Ribavirin) Inhalation Solution; Virazole (TN); AA-504/07617051; Ro 20-9963/000; Ro-20-9963; Ribavirin (JAN/USP/INN); 1-beta-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide; 1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide; RBI034 (2-5A antisense compound) + Ribavirin
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| Activity |
IC50 = 65880 nM
|
[1] | |||
| Compound Name |
Reserpine
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Approved | Compound Info | ||
| Synonyms |
Abesta; Abicol; Adelfan; Adelphin; Alkarau; Alkaserp; Alserin; Apoplon; Apsical; Ascoserp; Ascoserpina; Austrapine; Banasil; Banisil; Benazyl; Bioserpine; Brinderdin; Briserine; Broserpine; Cardioserpin; Carditivo; Carpacil; Carrserp; Darebon; Deserpine; Dralserp; Eberpine; Eberspine; Ebserpine; Elfanex; Elserpine; Enipresser; Escaspere; Eserpine; Eskaserp; Eskaserpine; Gammaserpine; Gilucard; Helfoserpin; Hexaplin; Hiposerpil; Hiserpia; Hydropine; Hydroserp; Hypersil; Hypersine; Hypertensan; Idoserp; Idsoserp; Interpina; Kitine; Klimanosid; Lemiserp; Loweserp; Mallopress; Maviserpin; Mayserpine; Mephaserpin; Modenol; Naquival; Nembuserpin; Neoserfin; Neoserp; Neoslowten; Orthoserpina; Perskleran; Pressimedin; Purserpine; Quiescin; Raucap; Raudiford; Raudixin; Raudixoid; Raugal; Raulen; Rauloydin; Raumorine; Raunervil; Raunorine; Raunova; Raupasil; Raupoid; Raurine; Rausan; Rausedan; Rausedil; Rausedyl; Rauserpin; Rauserpine; Rauserpol; Rausingle; Rautrin; Rauvlid; Rauwasedin; Rauwilid; Rauwiloid; Rauwipur; Rauwita; Rauwoleaf; Rawilid; Recipin; Regroton; Resaltex; Resedrex; Resedril; Reserbal; Resercaps; Resercen; Reserfia; Reserjen; Reserlor; Reserp; Reserpal; Reserpamed; Reserpanca; Reserpene; Reserpex; Reserpidefe; Reserpil; Reserpin; Reserpina; Reserpinum; Reserpka; Reserpoid; Reserpur; Reserutin; Resiatric; Residin; Residine; Resine; Resocalm; Resperin; Resperine; Respital; Restran; Rezerpin; Riserpa; Rivased; Rivasin; Rolserp; Roxel; Roxinoid; Roxynoid; Ryser; Salupres; Sandril; Sandron; Sedaraupin; Sedaraupina; Sederaupin; Sedserp; Seominal; Serfin; Serfolia; Serolfia; Serpalan; Serpaloid; Serpaneurona; Serpanray; Serpasil; Serpasol; Serpate; Serpazil; Serpazol; Serpedin; Serpen; Serpena; Serpentil; Serpentin; Serpentina; Serpicon; Serpil; Serpiloid; Serpilum; Serpine; Serpipur; Serpivate; Serpivite; Serpogen; Serpoid; Serpone; Serpyrit; Sertabs; Sertens; Sertensin; Sertina; Supergan; Tefaserpina; Temposerpine; Tensanyl; Tenserpinie; Tensional; Tensionorme; Tepserpine; Terbolan; Transerpin; Triserpin; Tylandril; Unilord; Unipres; VIXO; Esc aspere; Hydromox R; Hypercal B; Loweser p; Neose rfin; Rau sedyl; Renese R; Rese rpamed; Se rpate; V Serp; VI XO; Diupres 250; Diupres 500; ENT 50146; H 520; Hydropres 25; Hydropres 50; Hydrosine 25; R 0875; Apoplon (TN); Diupres-250; Diupres-500; Diurese-R; Diutensen-R; HYDRO-RESERP; Hydrap-ES; Hydromox-R; Key-serpine; L-Carpserp; Neo-serp; Rau-Sed; Renese-R; Rese-lar; Reser-ar; SK-Reserpine; T-Serp; Usaf cb-27; V-Serp; Vio-Serpine; Cam-Ap-Es; L"-Carpserp; R-e-s; Ser-A-Gen; 3P Reserp
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| Activity |
IC50 = 160000 nM
|
[2] | |||
| Compound Name |
Bisbenzimide (Hoechst 33258)
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Investigative | Compound Info | ||
| Synonyms |
Hoechst 33342; 23491-52-3; Bisbenzimide; hoechst33342; UNII-99KZS6CNZX; Ho 342; 2'-(4-Ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole; EINECS 245-691-1; 99KZS6CNZX; 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-benzimidazole; CHEMBL343002; CHEBI:51232; 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole; 2'-(4'-Ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bis-1H-benzimidazole trihydrochloride trihydrate
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
Netropsin
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Investigative | Compound Info | ||
| Synonyms |
Netropsin; Antibiotic 1142; Congocidine; Antibiotic T-1384; UNII-64B3O0RD7N; CHEMBL307767; 64B3O0RD7N; NSC 3067; CH-777-A; IA 887; BRN 0376913; K-117; 2814-A; T 1384; N,4'-Bi(pyrrole-2-carboxamide), N'-(2-carbamoylethyl)-4-((2-guanidinoacetimidoyl)amino)-1,1'-dimethyl-; F 6; 1H-Pyrrole-2-carboxamide, 4-((((aminoiminomethyl)amino)acetyl)amino)-N-(5-(((3-amino-3-iminopropyl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)-1-methyl-; BDBM17; AC1L1I7V; AC1Q5M1N; SCHEMBL197747; CTK8G1803; IDBIFFKSXLYUOT-UHFFFAOYSA-N; 63770-20-7 (hydrochloride
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| Activity |
IC50 = 62000 nM
|
[4] | |||
| Compound Name |
5,15-Bis(4-bromophenyl)-10,20-bis(4-pyridin-4-ylphenyl)-21,23-dihydroporphyrin
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4080916; BDBM50247526
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| Activity |
EC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
Tetraphenylporphyrin
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Investigative | Compound Info | ||
| Synonyms |
5,10,15,20-tetraphenylporphyrin; meso-Tetraphenylporphine; Tetraphenylporphine; meso-Tetraphenylporphyrin; 21H,23H-Porphine, 5,10,15,20-tetraphenyl-; 5,10,15,20-Tetraphenyl-21H,23H-porphine; 5,10,15,20-Tetraphenylporphine; meso-Tetraphenylporphyrine; CHEMBL436524; MFCD00011680; NSC 18506; NSC640184; NSC 640184; Tetraphenyl porphine; (5Z,10Z,14Z,19Z)-5,10,15,20-tetraphenyl-21,23-dihydroporphyrin; Porphine, 5,10,15,20-tetraphenyl-; meso-Tetra(phenyl)porphine; SCHEMBL30136; KSC486O8L; 5,15,20-Tetraphenylporphine; CHEMBL3039846; DTXSID2061272; CTK3I6785; Porphine,10,15,20-tetraphenyl-; BCP21699; C44H30N4; KS-00000H6M; NSC18506; STR04536; EINECS 213-025-9; ANW-48175; BDBM50247512; NSC-18506; SBB008950; STK569350; meso-Tetraphenylporphine, low chlorine; 5-10-15-20-(tetraphenyl)porphyrin; AKOS002375245; 21H, 5,10,15,20-tetraphenyl-; LS41397; MCULE-4990406871; NSC-640184; 5,10,15,20-tetrakis(phenyl)porphyrin; AK-40151; BR-40151; NCI60_013368; SY009714; .alpha.,.gamma.,.delta.-Tetraphenylporphine; CS-0022009; ST50223984; T1359; X0347; 5,10,15,20-Tetraphenyl-21H,23H-prophine; S-1987; 48865-EP2274983A1; 48865-EP2289897A1; 48865-EP2311841A1; 152531-EP2289897A1; .alpha.,.beta.,.gamma.,.delta.-Tetraphenylporphine; 5,10,15,20-Tetraphenyl-21H,23H-porphine, 97%; 5,10,15,20-TETRAPHENYL-21H,23H-PORPHYRIN; Porphine, 5,10,15,20-tetraphenyl- (VAN) (8CI); 5,10,15,20-Tetraphenyl-21H,23H-porphine, >=99%; meso-Tetraphenylporphyrine pound>>5,10,15,20-tetraphenylporphyrin
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| Activity |
EC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
6-(4-Methylpiperazin-1-yl)-2-[2-[4-(10-prop-2-ynoxydecoxy)phenyl]-3H-benzimidazol-5-yl]-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3973119
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
6-(4-Methylpiperazin-1-yl)-2-[2-[4-(12-prop-2-ynoxydodecoxy)phenyl]-3H-benzimidazol-5-yl]-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3953305
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2-[4-[[1-(4-Azidobutyl)triazol-4-yl]methoxy]phenyl]-6-(4-methylpiperazin-1-yl)-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4098769
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
5,10-Bis(4-bromophenyl)-15,20-dipyridin-4-yl-21,23-dihydroporphyrin
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4078465; BDBM50247524
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| Activity |
EC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
5,10,15,20-Tetra(4-pyridyl)-21H,23H-porphine
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Investigative | Compound Info | ||
| Synonyms |
meso-Tetra(4-pyridyl)porphine; 5,10,15,20-Tetra(4-pyridyl)porphyrin; 21H,23H-Porphine, 5,10,15,20-tetra-4-pyridinyl-; CHEMBL3040240; CHEMBL4084530; MFCD00009626; ACMC-209dy0; tetrakis(4-pyridyl)porphyrin; meso-Tetra-4-pyridylporphine; SCHEMBL245937; DTXSID4066121; CTK3J0985; EINECS 240-858-5; 8597AA; ANW-22342; BDBM50247529; STL557808; ZB0218; AKOS015854419; CS-W009590; GS-6400; MCULE-4540725925; KS-000015Q2; AK-62442; 5,10,15,20-(tetra-4-pyridyl)porphyrin; 5-10-15-20-(tetra-4-pyridyl)porphyrin; 5,10,15,20-tetra(pyridin-4-yl)porphyrin; BB 0261664; 21H,23H-Porphine,5,10,15,20-tetra-4-pyridinyl-; 5101520-Tetra(4-pyridyl)-21; 5,10,15,20-Tetra(4-pyridinyl)-21H,23H-porphyrin; 5,10,15,20-Tetra(4-pyridyl)-21H,23H-porphine, 97%; Tris(4,4'-dicarboxylicacid-2,2'-bipyridyl)rutheniuM(II) dichloride; (5Z,10Z,14Z,19Z)-5,10,15,20-tetrakis(4-pyridyl)-21,23-dihydroporphyrin
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| Activity |
EC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
6-(4-Methylpiperazin-1-yl)-2'-(4-(undec-10-ynyloxy)phenyl)-1H,3'H-2, 5'-bibenzo[d]imidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3581011; SCHEMBL17968532; BDBM50498273
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
6-(4-Methylpiperazin-1-yl)-2'-(4-(4-(prop-2-ynyloxy)butoxy)phenyl)-1H,3'H-2,5'-bibenzo[d]imidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3581012; SCHEMBL16586786; BDBM50498269
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
2'-(4-(Hex-5-ynyloxy)phenyl)-6-(4-methylpiperazin-1-yl)-1H,3'H-2,5'-bibenzo[d]imidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3581010; SCHEMBL16586611; BDBM50498272
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
4-Furan-2-yl-2,6-di-thiophen-2-yl-pyridine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL26696; BDBM50140694
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| Activity |
IC50 = 50000 nM
|
[7] | |||
| Compound Name |
6-(4-Methylpiperazin-1-yl)-2-[2-[4-(8-prop-2-ynoxyoctoxy)phenyl]-3H-benzimidazol-5-yl]-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3902093
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
6-(4-Methylpiperazin-1-yl)-2-[2-[4-(6-prop-2-ynoxyhexoxy)phenyl]-3H-benzimidazol-5-yl]-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3981132
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
10-(4-Bromophenyl)-5,15,20-tris(4-pyridyl)-21H,23H-porphyrin
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4105160; SCHEMBL3459764; BDBM50247527; 5,10,15-Tri(4-pyridinyl)-20-(4-bromophenyl)-21H,23H-porphyrin
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| Activity |
EC50 ~ 50000 nM
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[5] | |||
| Compound Name |
5,15-Bis(4-bromophenyl)-10,20-bis(4-pyridyl)-21H,23H-porphyrin
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4097456; BDBM50247531; J3.644.689G; 5,15-Bis(4-pyridinyl)-10,20-bis(4-bromophenyl)-21H,23H-porphyrin
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| Activity |
EC50 ~ 50000 nM
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[5] | |||
| Compound Name |
Chembl4165426
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Investigative | Compound Info | ||
| Synonyms |
BDBM50404818
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| Activity |
IC50 = 50930 nM
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[8] | |||
| Compound Name |
Aesculioside IVa
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094677; BDBM50317505
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| Activity |
IC50 = 51800 nM
|
[9] | |||
| Compound Name |
AesculiosideIV-23C1
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094358; BDBM50317510
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| Activity |
IC50 = 53000 nM
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[9] | |||
| Compound Name |
Aesculioside IIIf
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095026; BDBM50317515
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| Activity |
IC50 = 53700 nM
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[9] | |||
| Compound Name |
Ganoderic acid T-N
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205004; Ganoderic Acid X; BDBM50400784; ZINC85586056; (24E)-3beta-Hydroxy-15alpha-acetoxylanosta-7,9(11),24-triene-26-oic acid; 15alpha-Acetoxy-3beta-hydroxy-5alpha-lanosta-7,9(11),24-trien-26-oic acid
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| Activity |
IC50 = 55000 nM
|
[10] | |||
| Compound Name |
3-[2-(Dimethylamino)isopropoxy]benzo[b]naphtho[2,3-d]furan-6,11-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL396473; BDBM50201611
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| Activity |
IC50 = 59500 nM
|
[11] | |||
| Compound Name |
3-[[4-[Bis(1-hydroxy-3,4-dioxonaphthalen-2-yl)methyl]phenyl]-(1-hydroxy-3,4-dioxonaphthalen-2-yl)methyl]-4-hydroxynaphthalene-1,2-dione
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Investigative | Compound Info | ||
| Synonyms |
NSC-117027; NSC117027; NSC 117027; CHEMBL66033; ZINC95537917
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| Activity |
IC50 = 60000 nM
|
[12] | |||
| Compound Name |
Simocyclinone D8
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1235969; BDBM50395674
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| Activity |
IC50 = 60000 nM
|
[13] | |||
| Compound Name |
4-[4-[10-[4-(4-Aminophenyl)phenyl]-15,20-dipyridin-4-yl-21,23-dihydroporphyrin-5-yl]phenyl]aniline
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4070279; BDBM50247525
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| Activity |
EC50 = 63430 nM
|
[5] | |||
| Compound Name |
8-(2-(Diethylamino)ethoxy)benzofuro[3,2-g]quinoline-5,11-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL390904; BDBM50201616
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| Activity |
IC50 = 64300 nM
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[11] | |||
| Compound Name |
Chembl4176453
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Investigative | Compound Info | ||
| Synonyms |
BDBM50404951
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| Activity |
IC50 = 67530 nM
|
[8] | |||
| Compound Name |
(19S)-19-Ethyl-19-hydroxy-8-(morpholin-4-ylmethylideneamino)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL540090
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| Activity |
IC50 = 69000 nM
|
[14] | |||
| Compound Name |
Chembl4169913
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Investigative | Compound Info | ||
| Synonyms |
BDBM50404476
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| Activity |
IC50 = 70610 nM
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[8] | |||
| Compound Name |
Chembl4172657
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Investigative | Compound Info | ||
| Synonyms |
BDBM50404949
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| Activity |
IC50 = 72680 nM
|
[8] | |||
| Compound Name |
Chembl4164762
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Investigative | Compound Info | ||
| Synonyms |
BDBM50404859
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| Activity |
IC50 = 72770 nM
|
[8] | |||
| Compound Name |
Chembl4167621
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Investigative | Compound Info | ||
| Synonyms |
BDBM50404947
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| Activity |
IC50 = 73110 nM
|
[8] | |||
| Compound Name |
Chembl4168199
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Investigative | Compound Info | ||
| Synonyms |
BDBM50404460
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| Activity |
IC50 = 82030 nM
|
[8] | |||
| Compound Name |
Chembl4170688
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Investigative | Compound Info | ||
| Synonyms |
BDBM50404952
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| Activity |
IC50 = 82080 nM
|
[8] | |||
| Compound Name |
6-(1-Hydroxypentyl)-5,8-dimethoxy-1,4-naphthoquinone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL310795; SCHEMBL8859738; 6-(1-hydroxypentyl)-5,8-dimethoxynaphthalene-1,4-dione; BDBM50080279; 6-(1-Hydroxy-pentyl)-5,8-dimethoxy-[1,4]naphthoquinone
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| Activity |
IC50 = 83140 nM
|
[15] | |||
| Compound Name |
Chembl4165844
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Investigative | Compound Info | ||
| Synonyms |
BDBM50404950
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| Activity |
IC50 = 83250 nM
|
[8] | |||
| Compound Name |
Acetic acid 2-acetoxy-5-[2-(3,4-diacetoxy-benzoylamino)-phenylcarbamoyl]-phenyl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL46380; BDBM50142522
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| Activity |
IC50 = 88000 nM
|
[16] | |||
| Compound Name |
2-Thioxo-5-[(3,4,5-trimethoxyphenyl)methylene]-1,3-diazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623264; SCHEMBL15421273; ZINC183767; BDBM50049751; AKOS003193409; ST50978237
Click to Show/Hide
|
||||
| Activity |
EC50 = 93200 nM
|
[17] | |||
| Compound Name |
(5E)-5-[(4-Bromothiophen-2-yl)methylidene]-2-sulfanylideneimidazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623262; BDBM50018912
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(4R,7E)-7-(7-Chloro-2-oxo-1H-indol-3-ylidene)-4-ethyl-4-hydroxy-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL368601; BDBM50033770
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
N-Benzothiazol-2-yl-4-hydroxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296350; BDBM50142527; AKOS000212648
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(19S)-19-Ethyl-7-fluoro-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-10-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL352302; BDBM50033795
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
N-(2-Benzamidophenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44839; Benzamide,N'-1,2-phenylenebis-; NSC81574; Benzamide, N,N'-1,2-phenylenebis-; Cambridge id 5140043; NCIOpen2_009086; Oprea1_489566; SCHEMBL1110180; N,N'-1,2-phenylenedibenzamide; N,N'-(o-Phenylene)bisbenzamide; CTK9A3593; ZINC77974; DTXSID30282897; N,N'-dibenzoyl-o-phenylenediamine; NSC28628; BDBM50142508; N-(2-Benzoylamino-phenyl)-benzamide; NSC-28628; NSC-81574; AKOS001012034; MCULE-7179824720; N-[2-(Benzoylamino)phenyl]benzamide #; N-(2-(BENZOYLAMINO)PHENYL)BENZAMIDE; EU-0002139; ST50182791; SR-01000405395; phenyl-N-[2-(phenylcarbonylamino)phenyl]carboxamide; SR-01000405395-1; Z56788102
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(7E)-4-Ethyl-4-hydroxy-7-(1-methyl-2-oxoindol-3-ylidene)-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL171194; BDBM50033786
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
(7E)-4-Ethyl-4-hydroxy-7-(6-methoxy-2-oxo-1H-indol-3-ylidene)-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL368812; BDBM50033794
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
(5E)-5-[(3,5-Dimethylphenyl)methylidene]imidazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623276; BDBM50119352
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
Methyl (E)-3-[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl]prop-2-enoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL168505; SCHEMBL8480368; BDBM50291413
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
(5E)-5-(3,4-Dimethoxybenzylidene)-2-thioxoimidazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623263; SCHEMBL15421491; ZINC116010; BDBM50018914; AKOS000411914; ST50186883; 5-(3,4-dimethoxybenzylidene)-2-thiohydantoin; SR-01000438032; SR-01000438032-1; 5-[(3,4-dimethoxyphenyl)methylene]-2-thioxo-1,3-diazolidin-4-one; (5E)-5-[(3,4-dimethoxyphenyl)methylene]-2-thioxo-imidazolidin-4-one
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(5E)-5-[(4-Methoxy-3-methylphenyl)methylidene]imidazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623274; BDBM50119350; ZINC408917211
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(7E)-4-Ethyl-4-hydroxy-7-(5-nitro-2-oxo-1H-indol-3-ylidene)-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL354083; BDBM50033800
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
(5E)-5-[(4-Methoxy-3-methylphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623268; BDBM50081726; ZINC12473731
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
Acetic acid 2-acetoxy-5-[4-(3,4-diacetoxy-benzoylamino)-phenylcarbamoyl]-phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44680; BDBM50142518
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(4S,7E)-4-Ethyl-4-hydroxy-7-(2-oxo-1H-indol-3-ylidene)-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL353325; BDBM50033788
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
(4R,7E)-4-Ethyl-4-hydroxy-7-(6-methylsulfanyl-2-oxo-1H-indol-3-ylidene)-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL172268; BDBM50033790
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
5-(4-Methylbenzylidene)-2-thioxoimidazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623271; BDBM50095650; ZINC12410505; AKOS000411677; 5-(4-methylobenzylidene)-2-thiohydantoin; SR-01000396024; SR-01000396024-1; (5E)-5-(p-tolylmethylene)-2-thioxo-imidazolidin-4-one; 4-[(4-methylphenyl)methylidene]-2-sulfanyl-4,5-dihydro-1H-imidazol-5-one
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
Acetic acid 4-[2-(4-acetoxy-benzoylamino)-phenylcarbamoyl]-phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL45239; ChemDiv3_002284; MLS001196970; HMS1479H18; HMS2881M22; BDBM50142524; ZINC13118779; AKOS001649305; MCULE-3594625641; SMR000555709; BRD-K02432982-001-01-8; 4-[(2-{[4-(acetyloxy)benzoyl]amino}anilino)carbonyl]phenyl acetate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(4R,7E)-4-Ethyl-4-hydroxy-7-(7-methyl-2-oxo-1H-indol-3-ylidene)-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL367281; BDBM50033781
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
(4R,7E)-4-Ethyl-4-hydroxy-7-(5-methyl-7-nitro-2-oxo-1H-indol-3-ylidene)-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL367649; BDBM50033779
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
Acetic acid 4-[4-(4-acetoxy-benzoylamino)-phenylcarbamoyl]-phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL47848; SCHEMBL17570205; BDBM50142511
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Acetic acid 4-[3-(4-acetoxy-benzoylamino)-phenylcarbamoyl]-phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296856; BDBM50142516
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(19S)-19-Ethyl-19-hydroxy-8-(2-phenylethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL352709; BDBM50291414; (S)-4-Ethyl-4-hydroxy-10-phenethyl-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
(7E)-4-Ethyl-7-(6-fluoro-7-methyl-2-oxo-1H-indol-3-ylidene)-4-hydroxy-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL173820; BDBM50033782
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
4-Hydroxy-N-[4-[(4-hydroxybenzoyl)amino]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL294998; Oprea1_051408; SCHEMBL8420639; BDBM50142520; N-(4-Benzoylamino-4-hydroxyphenyl)-4-hydroxy-benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(E)-5-(3,4,5-Trimethoxybenzylidene)imidazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630442; NSC122482; ZINC228501; BDBM50332532; NSC-122482
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(7E)-4-Ethyl-4-hydroxy-7-(5,6,7-trifluoro-2-oxo-1H-indol-3-ylidene)-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL172860; BDBM50033793
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
N-(2-Benzoylamino-4-hydroxyphenyl)-4-hydroxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296797; BDBM50142512
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Gallanilide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3,4,5-Trihydroxybenzanilide; 3,4,5-trihydroxy-N-phenylbenzamide; CHEMBL43782; 2-12-00-00263 (Beilstein Handbook Reference); EINECS 228-417-5; N-Phenyl-3,4,5-trihydroxybenzamide; BRN 2740527; Gallanilid; Benzamide, N-phenyl-3,4,5-trihydroxy-; SCHEMBL1812080; CTK5B5400; DTXSID50211669; BDBM50142530; 3,4,5-Trihydroxy-N-phenyl-benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(5E)-5-(3-Methoxybenzylidene)-2-thioxoimidazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623269; BDBM50081727; ZINC12341251; AKOS000411675; SR-01000437820; SR-01000437820-1
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
5-[(3,4-Dimethoxyphenyl)methylidene]imidazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL139899; 5-(3,4-dimethoxybenzylidene)hydantoin; 5-(3,4-dimethoxybenzylidene)-hydantoin; SCHEMBL3125853; CTK6J7212; BDBM50115810; 5-(3',4'-dimethoxybenzal) hydantoin; MCULE-4501721533; 5-(3,4-dimethoxybenzylidene) -hydantoin; 5-(3,4-dimethoxybenzylidene)imidazolidine-2,4-dione
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-(3-Benzoylamino-4-hydroxyphenyl)-4-hydroxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296500; SCHEMBL729117; BDBM50142521; N,N'-(1,3-Phenylene)bis(4-hydroxybenzamide); 4-hydroxy-N-[3-[(4-hydroxybenzoyl)amino]phenyl]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(E)-9-Methoxy-11H-indeno[1,2-c]quinolin-11-oneO-2-morpholinoethyl Oxime
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243166; BDBM50326183
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
5-(4-Methoxybenzylidene)-2-thioxo-4-imidazolidinone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623270; 5-[(4-methoxyphenyl)methylene]-2-thioxo-1,3-diazolidin-4-one; SCHEMBL15421318; BDBM50095648; SBB039765; STK415773; ZINC12410530; (5E)-5-[(4-methoxyphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one; AKOS000271049; SDCCGMLS-0064594.P001; ST50055107; AB00075186-01; AH-034/32856014; (5E)-5-(4-methoxybenzylidene)-2-thioxo-4-imidazolidinone; (5E)-5-(4-methoxybenzylidene)-2-thioxoimidazolidin-4-one; 5-[(4-methoxyphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(11E)-11-[3-(Dimethylamino)propoxyimino]-9-methoxy-5H-indeno[1,2-c]quinolin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243199; BDBM50326182; (E)-6-Hydroxy-9-methoxy-11H-indeno[1,2-c]quinolin-11-one O-3-(Dimethylamino)propyl Oxime
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
(5E)-5-[[5-(6-Methoxypyridin-3-yl)thiophen-2-yl]methylidene]imidazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623272; BDBM50114770
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(7E)-7-(5-Chloro-2-oxo-1H-indol-3-ylidene)-4-ethyl-4-hydroxy-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL170409; BDBM50033773
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
(4R,7E)-4-Ethyl-4-hydroxy-7-[2-oxo-6-(trifluoromethoxy)-1H-indol-3-ylidene]-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL168994; BDBM50033774
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
9-Methoxy-11H-indeno[1,2-c]quinolin-11-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1240583; SCHEMBL3741119; BDBM50326188; 9-methoxyindeno[1,2-c]quinolin-11-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
(19S)-19-Ethyl-19-hydroxy-8-[(E)-2-phenylethenyl]-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL354671; BDBM50291411
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
(4R,7E)-7-(5-Bromo-2-oxo-1H-indol-3-ylidene)-4-ethyl-4-hydroxy-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL444352; BDBM50033792
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
(11E)-9-Methoxy-11-(2-morpholin-4-ylethoxyimino)-5H-indeno[1,2-c]quinolin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243264; BDBM50326190; (E)-6-Hydroxy-9-methoxy-11H-indeno[1,2-c]quinolin-11-one O-2-Morpholinoethyl Oxime
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
(4S,7E)-4-Ethyl-7-(5-fluoro-2-oxo-1H-indol-3-ylidene)-4-hydroxy-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL171364; BDBM50033777
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
(5E)-5-[[4-(6-Methoxypyridin-3-yl)thiophen-2-yl]methylidene]imidazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623273; BDBM50114772
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(5E)-5-[(4-Bromothiophen-2-yl)methylidene]imidazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623275; ZINC1095129; BDBM50119351
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(5E)-5-[(4-Nitrophenyl)methylidene]-2-sulfanylideneimidazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623267; ZINC187173; BDBM50049758; STL428177; AKOS000411853; 5-(4-nitrobenzylidene)-2-thiohydantoin; ST51022661; (5E)-5-(4-nitrobenzylidene)-2-thioxoimidazolidin-4-one; 5-[(4-nitrophenyl)methylene]-2-thioxo-1,3-diazolidin-4-one; (5E)-5-[(4-nitrophenyl)methylene]-2-thioxo-imidazolidin-4-one
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
5-(4-Methylbenzylidene)imidazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623277; 5-[(4-methylphenyl)methylidene]imidazolidine-2,4-dione; ZINC72876; BDBM50119353; AKOS000417851; NE57669; SR-01000491740; J-002326; SR-01000491740-1; (5E)-5-(4-methylbenzylidene)imidazolidine-2,4-dione; 2,4-Imidazolidinedione, 5-[(4-methylphenyl)methylene]-
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(11E)-9-Methoxy-11-(2-piperidin-1-ylethoxyimino)-5H-indeno[1,2-c]quinolin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243230; BDBM50326189; (E)-6-Hydroxy-9-methoxy-11H-indeno[1,2-c]quinolin-11-one O-2-(Piperidin-1-yl)ethyl Oxime
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
Ganoderiol F
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
26,27-Dihydroxylanosta-7,9(11),24-trien-3-one; CHEMBL1915761; SCHEMBL902833; DTXSID00921423; BDBM50356920; ZINC32023197; AKOS032948622; W2475
Click to Show/Hide
|
||||
| Activity |
IC50 = 106000 nM
|
[10] | |||
| Compound Name |
Aesculioside IIa
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094691; Aesculioside G5; BDBM50317532
Click to Show/Hide
|
||||
| Activity |
IC50 = 109300 nM
|
[9] | |||
| Compound Name |
Kaempferol 3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1929193; Kaempferol-3-O-beta-glucopyranosyl-7-O-alpha-rhamnopyranoside; Kaem-3-Glc-7-Rha; SCHEMBL9993267; Kampferol 3-glucoside 7-rhamnoside; Kaempferol-3-glucoside-7-rhamnoside; BDBM50359314; ZINC67902860; MCULE-2511510719; kaempferol 3-O-glucoside 7-O-rhamnoside; Q27137238; Kaempferol-3-O-beta-D-glucoside-7-O-alpha-L-rhamnoside; kaempferol 3-O- -D-glucopyranosyl-7-O- -L-rhamnopyranoside; kaempferol-3-O-beta-D-glucopyranoside-7-O-alpha-L-rhamnopyranoside; 4H-1-Benzopyran-4-one, 7-[(6-deoxy-; A-L-mannopyranosyl)oxy]-3-(; A-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[21] | |||
| Compound Name |
Aesculioside IIc
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095014; BDBM50317519
Click to Show/Hide
|
||||
| Activity |
IC50 = 110500 nM
|
[9] | |||
| Compound Name |
6-(1-Hydroxyethyl)-5,8-dimethoxy-1,4-naphthoquinone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL78344; SCHEMBL8859706; 6-(1-hydroxyethyl)-5,8-dimethoxynaphthalene-1,4-dione; BDBM50080278; 6-(1-Hydroxy-ethyl)-5,8-dimethoxy-[1,4]naphthoquinone
Click to Show/Hide
|
||||
| Activity |
IC50 = 110630 nM
|
[15] | |||
| Compound Name |
Aesculioside IIIa
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094690; BDBM50317521
Click to Show/Hide
|
||||
| Activity |
IC50 = 118700 nM
|
[9] | |||
| Compound Name |
3-[(E)-4-Nitrobenzylidene]benzofuran-2(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL370969; BDBM50410154
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[22] | |||
| Compound Name |
6-(1-Hydroxypropyl)-5,8-dimethoxy-1,4-naphthoquinone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL79103; SCHEMBL8859739; 6-(1-hydroxypropyl)-5,8-dimethoxynaphthalene-1,4-dione; BDBM50080284; 6-(1-Hydroxy-propyl)-5,8-dimethoxy-[1,4]naphthoquinone
Click to Show/Hide
|
||||
| Activity |
IC50 = 121830 nM
|
[15] | |||
| Compound Name |
6-(1-Hydroxybutyl)-5,8-dimethoxy-1,4-naphthoquinone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL421321; SCHEMBL8859694; 6-(1-hydroxybutyl)-5,8-dimethoxynaphthalene-1,4-dione; BDBM50080283; 6-(1-Hydroxy-butyl)-5,8-dimethoxy-[1,4]naphthoquinone
Click to Show/Hide
|
||||
| Activity |
IC50 = 129700 nM
|
[15] | |||
| Compound Name |
Aesculioside IIIc
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095341; BDBM50317512
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|
||||
| Activity |
IC50 = 131700 nM
|
[9] | |||
| Compound Name |
[(3R,4S,5R)-3,4-Dihydroxy-5-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-3-yl]oxyoxolan-3-yl]methyl acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1929025; BDBM50359309
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|
||||
| Activity |
IC50 = 150000 nM
|
[21] | |||
| Compound Name |
Aesculioside IIIb
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094683; BDBM50317527
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|
||||
| Activity |
IC50 = 160000 nM
|
[9] | |||
| Compound Name |
(E)-3-(3,4-Dihydroxybenzylidene)benzofuran-2(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL195143; BDBM50410156
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|
||||
| Activity |
IC50 = 160000 nM
|
[22] | |||
| Compound Name |
Kaempferol 3-O-beta-D-galactopyranosyl-7-O-alpha-L-rhamnopyranoside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1929192; Kaempferol-3-O-beta-D-galactoside-7-O-alpha-L-rhamnoside; Kaempferol 3-galactoside-7-rhamnoside; Kaem-3-Gal-7-Rha; Astragalin 7-rhamnoside; Kaempferol 3-glucoside 7-rhamnoside; BDBM50359313; Kaempferol 3-galactoside 7-rhamnoside; kaempferol-3-galactoside-7-rhamnoside; Kaempferol 3-O-galactoside 7-O-rhamnoside; Q27137237
Click to Show/Hide
|
||||
| Activity |
IC50 = 180000 nM
|
[21] | |||
| Compound Name |
4-Furan-2-yl-2-((E)-2-furan-2-yl-vinyl)-6-thiophen-2-yl-pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL27322; BDBM50140695
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[7] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 62 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Doxorubicin
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
doxorubicin; 23214-92-8; Doxil; Doxorubicine; Adriablastin; Doxorubicinum; 14-Hydroxydaunomycin; 14-Hydroxydaunorubicine; Doxorubicina; Adriamycin semiquinone; Doxorubicinum [INN-Latin]; Doxorubicine [INN-French]; Doxorubicina [INN-Spanish]; Myocet; FI 106; Doxorubicin [USAN:INN:BAN]; CCRIS 739; NDC 38242-874; HSDB 3070; UNII-80168379AG; NCI-C01514; EINECS 245-495-6; CHEMBL53463; CHEBI:28748; 5,12-Naphthacenedione,; ADM; ADR; ThermoDox; Aerosolized Doxorubicin; Doxorubicin citrate; RDF Rubex; Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74; DM2; JT9100000; Adiblastine (hydrochloride salt); Adr iablatina (hydrochloride salt); Adriablastine (hydrochloride salt); Adriablatina (hydrochloride salt); Adriacin (hydrochloride salt); Adriamycin PFS (TN); Adriamycin PFS (hydrochloride salt); Adriamycin RDF (TN); Adriamycin RDF (hydrochloride salt); Adriblastina (TN); Adriblastina (hydrochloride salt); Adriblatina (hydrochloride salt); Caelyx (TN); Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120; DOX-SL; Doxorubicin hydrochloride (hydrochloride salt); Doxorubicin-hLL1; Doxorubicin-hLL1 conjugate; Farmablastina (hydrochloride salt); Hydroxydaunomycin hydrochlor ide (hydrochloride salt); Hydroxydaunomycin hydrochloride (hydrochloride salt); Hydroxydaunorubicin hydrochloride (hydrochloride salt); Myocet (TN); Rubex (TN); Rubex (hydrochloride salt); TLC D-99; Doxorubicin (USAN/INN); Doxorubicin-P4/D10; Doxorubicin-P4/D10 conjugate; Cantide + adriamycin
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|
||||
| Activity |
IC50 > 200000 nM
|
[23] | |||
| Compound Name |
Etoposide
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|
Approved | Compound Info | ||
| Synonyms |
etoposide; 33419-42-0; VePesid; Toposar; trans-Etoposide; Lastet; (-)-Etoposide; Zuyeyidal; Etoposidum; Etoposido; Vepesid J; Eposin; Etoposidum [INN-Latin]; Etoposide (VP16); VP 16-213; VP 16 (pharmaceutical); Etoposido [INN-Spanish]; Etopophos (phosphate salt); VP-16-213; 4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside; VP 16213; UNII-6PLQ3CP4P3; NK 171; NSC 141540; CCRIS 2392; HSDB 6517; 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside); EINECS 251-509-1; NSC-141540; Eposide; Etopol; Etosid; Vepeside; Demethyl EpipodophyllotoxinEthylidine Glucoside; E0675; Demethyl-epiodophyllotoxin ethylidene glucoside; Epipodophyllotoxin VP-16213; Eposin (TN); Etopophos (TN); Trans-Etoposide; VePESID (TN); Vepesid (TN); DEMETHY-EPIPODOPHYLLOTOXIN, ETHYLIDENE GLUCOSIDE; VP-16 (TN); Demethylepipodophyllotoxin-beta-D-ethylideneglucoside; Etoposide (JP15/USP/INN); Etoposide [USAN:INN:BAN:JAN]; Eposin, Vepesid, VP-16, Toposar, Etoposide; Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside; Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI); Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside); 4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside; 4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside); 4'-Demethylepipodophyllotoxin ethylidene-beta-D-glucoside; 4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin; 4-Demethylepipodophyllotoxin-beta-D-ethylideneglucoside
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|
||||
| Activity |
IC50 > 1000000 nM
|
[2] | |||
| Compound Name |
ginsenoside Rg3
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|
Investigative | Compound Info | ||
| Synonyms |
(20S)-ginsenoside Rg3
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||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
6H-Purin-6-one, 2-((3,4-dichlorophenyl)amino)-1,9-dihydro-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL51613; 6H-Purin-6-one,2-[(3,4-dichlorophenyl)amino]-1,9-dihydro-; 6H-Purin-6-one, 2-[(3,4-dichlorophenyl)amino]-1,9-dihydro-; ACMC-20mqvl; CTK4B3711; DTXSID70924668; BDBM50013091; 2-(3,4-dichloroanilino)-1,9-dihydropurin-6-one; 2-(3,4-Dichlorophenylamino)-9H-purin-6(1H)-one; 2-((3,4-Dichlorophenyl)amino)-1H-purin-6(9H)-one; 2-(3,4-Dichloro-phenylamino)-1,9-dihydro-purin-6-one; 2-[(3,4-Dichlorophenyl)imino]-3,9-dihydro-2H-purin-6-ol
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[24] | |||
| Compound Name |
N~2~-(3,4-Dichlorophenyl)-9H-purine-2,6-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC681687; CHEMBL53605; BDBM50034955; NSC-681687; NCI60_029180; N-(3,4-Dichlorophenyl)-9H-purine-2,6-diamine; N2-(3,4-dichlorophenyl)-9H-purine-2,6-diamine; N~2~-(3,4-Dichlorophenyl)-9H-purine-2,6-diamine; N*2*-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[24] | |||
| Compound Name |
2,4-Pyrimidinediamine, 6-chloro-N4-(3,4-dichlorophenyl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC43273; CHEMBL53912; NSC 43273; 6-chloro-n4-(3,4-dichlorophenyl)pyrimidine-2,4-diamine; DTXSID00222780; ZINC1675992; BDBM50034961; NSC-43273; AKOS019303096; 2-amino-4-chloro-6-(3',4'-dichloroanilino)pyrimidine; N'-(3,4-Dichlorophenyl)-6-chloro-2,4-pyrimidinediamine; 6-Chloro-N*4*-(3,4-dichloro-phenyl)-pyrimidine-2,4-diamine
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[24] | |||
| Compound Name |
Kaempferol 3-O-[alpha-L-rhamnopyranosyl(1->2)-beta-D-glucopyranosyl]-7-O-alpha-L-rhamnopyranoside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1929027; Kaempferol-3-Glucoside-2''-Rhamnoside-7-Rhamnoside; Kaem-3-Glc-2''-Rha-7-Rha; BDBM50359311; Kaempferol 3-O-Rha(1-2)Glc 7-O-Rha; Kaempferol-3-Glucoside-2-Rhamnoside,-7-Rhamnoside?; Q27137235
Click to Show/Hide
|
||||
| Activity |
IC50 = 220000 nM
|
[21] | |||
| Compound Name |
3-O-beta-6-Deoxy-D-glucopyranosyl cincholic acid28-O-beta-D-glucopyranosyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095350; BDBM50317555
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|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Quinovic acid 28-O-beta-D-glucopyranosyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095349; BDBM50317556
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|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Aesculioside IIj
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095339; Aesculioside G15; BDBM50317513
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
[(3R,4R,4Ar,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5,10-dihydroxy-4a-(hydroxymethyl)-2,2,6a,6b,9,9,12a-heptamethyl-3-[(Z)-2-methylbut-2-enoyl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-4-yl] 2-methylbutanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094680; BDBM50317502; 21-O-Angeloyl-22-O-(2-methylbutanoyl)-3beta,16alpha,28-trihydroxyolean-12-ene
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Ginsenoside Re
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
Ginsenoside B2; Panaxoside RE; ginsenoside-Re; UNII-46F3R0BL3I; Chikusetsusaponin IVc; NSC 308877; 46F3R0BL3I; CHEMBL510095; MFCD00133369; EINECS 257-814-6; NSC-308877; (20S)-ginsenoside Re; SCHEMBL669738; CTK8F0918; HY-N0044; BDBM50378779; s3811; AKOS025310861; ZINC242620164; CCG-270589; CS-3838; DB14815; C08944; 286G596; A829010; Q27105064; UNII-3K198YD54P component PWAOOJDMFUQOKB-WCZZMFLVSA-N; Ginsenoside-Re from Panax ginseng (Korean ginseng) root, triterpenoid saponin
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
[(3R,4R,4Ar,5S,6R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5,6,10-trihydroxy-4a-(hydroxymethyl)-2,2,6a,6b,9,9,12a-heptamethyl-3-[(Z)-2-methylbut-2-enoyl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-4-yl] 2-methylbutanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094678; BDBM50317504; 21-O-Angeloyl-22-O-(2-methylbutanoyl)-3beta,15alpha,16alpha,28-tetrahydroxyolean-12-ene
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
20(S)-Ginsenoside Rg2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095005; BDBM50317543
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Gypenoside VIII
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
UNII-WB232T95AV; CHEMBL473659; WB232T95AV; GS-Rd; (20S)-ginsenoside Rd; (GS)-Rd; SCHEMBL669260; HMS3885A14; HY-N0043; BDBM50317539; s3931; AKOS037514671; ZINC253387933; CCG-270588; CS-3839; C20725; Q27136471
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Ginsenoside F2
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095007; ginsenoside-F2; 20(S)-Ginsenoside F2; 20(S)-Ginsenoside-F2; Sg(S)-ginsenoside f2; (20S)-ginsenoside F2; 20-(S)-Ginsenoside F2; SCHEMBL17576511; DTXSID20432763; BDBM50317538; MFCD06410948; s9044; ZINC96095534; AKOS037514666; CCG-270474; AB0029015; HY-125848; CS-0009605; N1568; X1142; C20779; 025S494; Q-100717; Q27146699; 3beta,20-bis(beta-D-glucopyranosyloxy)dammar-24-en-12beta-ol
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
[(3R,4R,4Ar,5R,6aR,6aS,6bR,8aR,9S,10S,12aR,14bS)-4,5,10-trihydroxy-4a,9-bis(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-3-yl] (Z)-2-methylbut-2-enoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095017; BDBM50317517; 21-O-Angeloy-3beta,16alpha,22alpha,24,28-pentahydroxyolean-12-ene
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
2, 3-Dihydroxy-12-ursen-28-oic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1097033; BDBM50317549
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Eryngioside 94A
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094692; BDBM50317520
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|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
20(R)-Ginsenoside Rg2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095006; BDBM50317542
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Quinovic acid 3-O-beta-D-glucoside
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL508407; BDBM50317554; C36H56O10; ZINC49899430; AKOS032962167; 3-o-beta-d-glucopyranosyl quinovic acid; W2593; 3beta-(beta-D-Glucopyranosyloxy)urs-12-ene-27,28-dioic acid
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Eryngioside E
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095019; BDBM50317533
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|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Eryngiioside L
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094687; BDBM50317523
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|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Gypenoside XVII
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
GYPENOSIDE-XVII; Gynosaponin S; Ginsenoside XVII; CHEMBL504441; HMS3887K09; HY-N0553; MFCD10566703; s9207; AKOS027251125; ZINC253387973; CCG-270587; CS-4163; N2767; Y0100; C20736; Q27146716
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
3-[(E)-4-Hydroxybenzylidene]benzofuran-2(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL371047; BDBM50410152
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[22] | |||
| Compound Name |
(1S,2R,4As,6aR,6bR,8aR,10S,12aR,12bR,14bS)-1,2,6b,9,9,12a-hexamethyl-10-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-4a-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)carbonyl)-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-6a-carboxylic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL501302; Zygophyloside E; BDBM50317552; ZINC96171514; 3-O-beta-D-glucopyranosyl quinovic acid28-O-beta-D-glucopyranosyl ester
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Eryngioside F
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095018; BDBM50317530
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|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Aesculioside IIk
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094689; Aesculioside G16; BDBM50317522
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
(1S,2R,4As,6aR,6aR,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-1,2,6b,9,9,12a-hexamethyl-4a-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycarbonyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-6a-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095352; BDBM50317551
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Saniculasaponin III
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094686; BDBM50317524
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Aesculioside IIf
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095340; Aesculioside G13; BDBM50317529
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Ginsenoside F3
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095004; Ginsenoside-F3; HY-N0600; BDBM50317544; ZINC95548971; AKOS027251121; CS-0009606; N2377; Y0088
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Kaempferol 3-O-alpha-L-arabinopyranosyl-7-O-alpha-L-rhamnopyranoside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1929026; BDBM50359310; Q27137234; 3-(alpha-L-Arabinopyranosyloxy)-4',5-dihydroxy-7-(alpha-L-rhamnopyranosyloxy)flavone
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[21] | |||
| Compound Name |
21beta-O,22alpha-O-Diangeloylbarringtogenol C
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094676; BDBM50317506; 21,22-O-Diangeloyl-3beta,16alpha,28-trihydroxyolean-12-ene
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
(1S,2R,4As,6aR,6aR,6bR,8aR,10S,12aR,14bS)-4a-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxycarbonyl-1,2,6b,9,9,12a-hexamethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-6a-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095353; BDBM50317550
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
[(3R,4R,4Ar,5R,6aR,6aS,6bR,8aR,9S,10S,12aR,14bS)-5,10-dihydroxy-4a,9-bis(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-4-(2-methylpropanoyloxy)-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-3-yl] (Z)-2-methylbut-2-enoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094682; BDBM50317528; 21-O-Angeloyl-22-O-(2-methylbutanoyl)-3beta,16alpha,24,28-tetrahydroxyolean-12-ene
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Unii-W6V49A8fjq
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
W6V49A8FJQ; CHEMBL507688; HY-N0041; BDBM50317540; Ginsenoside Rb3, analytical standard; MFCD10566396; s9208; AKOS037514669; CCG-270634; CS-3831; NCGC00485982-01; Q27146709
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Ginsenoside-F5
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL583152; BDBM50378778
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
(20R)-Ginsenoside Rg3
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
20(R)-ginsenoside Rg3; CHEMBL1095008; (R)Ginsenoside-Rg3; (20R)Ginsenoside Rg3; 20(R)-propanaxidiol; (R)-Ginsenoside Rg3; BDBM50317536; MFCD11045225; s9021; ZINC96085899; AKOS027251123; CCG-270473; X6589; Q27136474
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
[(3R,4R,4Ar,5R,6aR,6aS,6bR,8aR,9S,10S,12aR,14bS)-5,10-dihydroxy-4a,9-bis(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-4-[(Z)-2-methylbut-2-enoyl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicen-3-yl] (Z)-2-methylbut-2-enoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094673; BDBM50317509; 21,22-O-Diangeloy-3beta,16alpha,24,28-tetrahydroxyolean-12-ene
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
alpha-Amyrin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Viminalol; alpha-Amyrenol; alpha-Amyrine; Urs-12-en-3beta-ol; UNII-30ZAG40J8N; 5alpha-urs-12-en-3beta-ol; (3beta)-urs-12-en-3-ol; 30ZAG40J8N; CHEMBL455357; MFCD00016754; alfa-Amyrin; A-amyrin with hplc; EINECS 211-352-1; NSC 114787; urs-12-ene-3beta-ol; SCHEMBL377781; alpha-Amyrin, analytical standard; (3.beta.)-Urs-12-en-3-ol; ZINC4097713; 6930AF; BDBM50241956; AKOS024319514; LMPR0106170001; (3?)?-Urs-?12-?en-?3-?ol; Urs-12-en-3-ol, (3beta)- (9CI); C08615; 638A959; Q2501558
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Damara-20(22), 24-dien-3, 6, 12-trine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1096728; SCHEMBL16701871; BDBM50317534
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Aesculioside IIg
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094688; Aesculioside G14; BDBM50317531
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Eryngiioside J
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094685; BDBM50317525
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Ginsenoside rb1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Gynosaponin C; ginsenoside-Rb1; Sanchinoside E1; Panax saponin E; Arasaponin E1; Pseudoginsenoside D; Gypenoside III; Panaxsaponin E; UNII-7413S0WMH6; (20S)-ginsenoside Rb1; CHEMBL501515; GRb 1; 7413S0WMH6; MFCD00133367; EINECS 255-532-8; C54H92O23; NSC 310103; GSRb1; GS-Rb1; 20(S)-ginsenoside Rb1; BIDD:ER0108; HMS3885O12; HY-N0039; BDBM50317541; s3924; AKOS025311537; CCG-270640; CS-3829; DB06749; AB0016710; N1620; C20713; 753G439; Q-100470; Ginsenoside Rb1, primary pharmaceutical reference standard; Ginsenoside Rb1, European Pharmacopoeia (EP) Reference Standard; Ginsenoside-Rb1 from Panax ginseng (Korean ginseng) root, triterpenoid saponin
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Aesculioside III
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1094684; BDBM50317526
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
3-O-alpha-L-Rhamnopyranosyl quinovic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095351; BDBM50317553
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[9] | |||
| Compound Name |
Kaempferol 3-O-[alpha-L-rhamnopyranosyl(1->2)-beta-D-galactopyranosyl]-7-O-alpha-L-rhamnopyranoside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1926685; BDBM50359312; Q27137236
Click to Show/Hide
|
||||
| Activity |
IC50 = 260000 nM
|
[21] | |||
| Compound Name |
(3E)-3-[(3-Hydroxyphenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL194829; BDBM50410164
Click to Show/Hide
|
||||
| Activity |
IC50 = 262000 nM
|
[22] | |||
| Compound Name |
3-[(E)-4-Hydroxybenzylidene]-6-hydroxybenzofuran-2(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL195416; SCHEMBL15426107; BDBM50164888; 6-Hydroxy-3-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene]-3H-benzofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 307000 nM
|
[22] | |||
| Compound Name |
(3E)-3-[(4-Fluorophenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL364033; BDBM50410163
Click to Show/Hide
|
||||
| Activity |
IC50 = 392000 nM
|
[22] | |||
| Compound Name |
4-Furan-2-yl-2-thiophen-2-yl-pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL282299; BDBM50140699
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[7] | |||
| Compound Name |
2,4,6-Tri-furan-2-yl-pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL440281; BDBM50140691
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[7] | |||
| Compound Name |
(3E)-5-Hydroxy-3-[(4-hydroxyphenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL426092; BDBM50410159
Click to Show/Hide
|
||||
| Activity |
IC50 = 555000 nM
|
[22] | |||
| Compound Name |
[(1R)-1-(5,8-Dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL8937; Retinoic acid (R)-1-[(1,4-dioxo-5,8-dihydroxy-1,4-dihydronaphthalen)-2-yl]-4-methyl-3-pentenyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 > 625000 nM
|
[25] | |||
| Compound Name |
(3E)-3-[(4-Hydroxy-3-methoxyphenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL372372; BDBM50410155
Click to Show/Hide
|
||||
| Activity |
IC50 = 630000 nM
|
[22] | |||
| Compound Name |
(3E)-3-[(3-Hydroxy-4-methoxyphenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL381195; BDBM50410160
Click to Show/Hide
|
||||
| Activity |
IC50 = 800000 nM
|
[22] | |||
| Compound Name |
(3E)-3-Benzylidene-5-hydroxy-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL381410; BDBM50410151
Click to Show/Hide
|
||||
| Activity |
IC50 = 960000 nM
|
[22] | |||
| Compound Name |
Ethyl 2-[4-[(E)-(2-oxo-1-benzofuran-3-ylidene)methyl]phenyl]acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL193628; BDBM50410162
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[22] | |||
| Compound Name |
Elaidic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
trans-9-Octadecenoic acid; trans-Oleic acid; (E)-octadec-9-enoic acid; 9-octadecenoic acid; (E)-Oleic acid; 9-Octadecenoic acid, (E)-; 9-octadecenoic acid, (9E)-; trans-Octadec-9-enoic acid; (9E)-octadec-9-enoic acid; trans-Elaidic acid; Elaidinsaeure; Elaidinsaure; acide elaidique; 9-elaidic acid; MFCD00063954; Octadec-9-enoic acid; 9E-octadecenoic acid; UNII-4837010H8C; trans-.DELTA.9-Octadecenoic acid; (9E)-Octadecenoic acid; 9-trans-Octadecenoic acid; D9-trans-Octadecenoic acid; trans-D9-Octadecenoic acid; Delta(9)-octadecenoic acid; 9-Octadecenoic acid,(9E)-; CHEMBL460657; trans-Delta(9)-octadecenoic acid; NSC26988; Elaidic acid, 98%; C18:1, n-9; trans-.delta.(sup 9)-Octadecenoic acid; 4837010H8C; 18:1, n-9; Pamolyn; 9 Octadecenoic Acid; delta9-Octadecenoic acid; EINECS 204-006-6; NSC 26988; (E)-9-Octadecenoic acid; Delta(9)-octadecenoate; trans-delta(sup 9)-Octadecenoic acid; Elaidinic acid; oleic_acid; AI3-15840; elaidic acid group; EINECS 217-977-6; Oleic Acid 213 NF; Oleic Acid 221 NF; Oleic Acid 233 LL; cis 9 Octadecenoic Acid; Canola Fatty Acid 790; bmse000643; (9E)octadec-9-enoic acid; Octadec-9-enoic acid anion; SCHEMBL1139; SCHEMBL6693; WLN: QV8U9-T; DTXSID8058619; Elaidic acid, analytical standard; HMS3649H19; Elaidic acid, >=99.0% (GC); ZINC8217338; 1749AH; 6479AF; BDBM50250904; CCG-35462; LMFA01030073; NSC-26988; s3357; STL282737; 9-Octadecenoic acid, (E)- (9CI); Elaidic acid, analytical sample grade; AKOS000278123; cis-9-Octadecenoic Acid, Elainic Acid; DB04224; FS-4659; NCGC00344330-02; ST098716; HY-113016; CS-0059361; O0010; EN300-19543; C01712; W-1404; L001099; Q413491; SR-01000946663; J-002839; Q-201508; SR-01000946663-1; D89C6CAA-1C31-4C71-BD3B-EA155A22E10C; Oleic Acid, 99% min (animal-origin free, vegetal-derived); Benzenebutanoic acid, 2-methyl-.alpha.,.gamma.-dioxo-, ethyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[26] | |||
| Compound Name |
(E)-3-Benzylidenebenzofuran-2(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL191804; BDBM50410161; (3E)-3-benzylidene-1-benzofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[22] | |||
| Compound Name |
(3E)-3-[(4-Methoxyphenyl)methylidene]-1-benzofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL191658; BDBM50410157
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[22] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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| REF 12 | Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease. J Med Chem. 1996 Jun 21;39(13):2472-81. | ||||
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| REF 14 | Synthesis and antitumor activity of a new class of water soluble camptothecin derivatives. Bioorg Med Chem Lett. 1996 Mar 19;6(6):671-4. | ||||
| REF 15 | Naphthazarin derivatives (II): formation of glutathione conjugate, inhibition of DNA topoisomerase-I and cytotoxicity. Bioorg Med Chem Lett. 1999 Aug 16;9(16):2407-12. | ||||
| REF 16 | Inhibitory activities against topoisomerase I and II by polyhydroxybenzoyl amide derivatives and their structure-activity relationship. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1669-72. | ||||
| REF 17 | Design, synthesis and evaluation of thiohydantoin derivatives as potent topoisomerase I (Top1) inhibitors with anticancer activity. Eur J Med Chem. 2015 Sep 18;102:540-51. | ||||
| REF 18 | Rigid analogs of camptothecin as DNA topoisomerase I inhibitors. J Med Chem. 1995 Mar 17;38(6):906-11. | ||||
| REF 19 | Synthesis and cytotoxic activity of alkylidene- and alkyl-substituted camptothecins. Bioorg Med Chem Lett. 1997;7(7):847-50. | ||||
| REF 20 | Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives. Part 2. J Med Chem. 2010 Aug 26;53(16):6164-79. | ||||
| REF 21 | Catalytic inhibition of eukaryotic topoisomerases I and II by flavonol glycosides extracted from Vicia faba and Lotus edulis. J Nat Prod. 2011 Nov 28;74(11):2362-70. | ||||
| REF 22 | Inhibitory activities against topoisomerase I and II by isoaurostatin derivatives and their structure-activity relationships. Bioorg Med Chem Lett. 2005 Apr 15;15(8):2065-8. | ||||
| REF 23 | Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba. J Nat Prod. 2001 Feb;64(2):204-7. | ||||
| REF 24 | Inhibition of herpes simplex virus type 1 helicase-primase by (dichloroanilino)purines and -pyrimidines. J Med Chem. 1995 May 12;38(10):1820-5. | ||||
| REF 25 | Acylshikonin analogues: synthesis and inhibition of DNA topoisomerase-I. J Med Chem. 1995 Mar 17;38(6):1044-7. | ||||
| REF 26 | Total synthesis and biological evaluation of (5Z,9Z)-5,9-hexadecadienoic acid, an inhibitor of human topoisomerase I. J Nat Prod. 2002 Nov;65(11):1715-8. | ||||
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