Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T13057 | Target Info | |||
| Target Name | Protein-tyrosine phosphatase SHP-2 (PTPN11) | ||||
| Synonyms |
Tyrosine-protein phosphatase non-receptor type 11; SHPTP2; SHP2; SHP-2; SH-PTP3; SH-PTP2; Protein-tyrosine phosphatase SHP2; Protein-tyrosine phosphatase 2C; Protein-tyrosine phosphatase 1D; PTP2C; PTP-2C; PTP-1D
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| Target Type | Clinical trial Target | ||||
| Gene Name | PTPN11 | ||||
| Biochemical Class | Phosphoric monoester hydrolase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 183 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
OLEANOLIC_ACID
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|
Investigative | Compound Info | ||
| Synonyms |
OLEANOLIC ACID; Oleanic acid; 508-02-1; Caryophyllin; Astrantiagenin C; Giganteumgenin C; Virgaureagenin B; 3beta-Hydroxyolean-12-en-28-oic acid; UNII-6SMK8R7TGJ; CCRIS 6493; (3-beta)-3-Hydroxyolean-12-en-28-oic acid; EINECS 208-081-6; NSC114945; 6SMK8R7TGJ; NSC-114945; 3-beta-Hydroxyolean-12-en-28-oic acid; CHEBI:37659; Olean-12-en-28-oic acid, 3-hydroxy-, (3beta)-; oleonolic acid; MFCD00064914
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| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
N-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-1-methyl-2-thien-2-ylethyl}-N'-(pyridin-3-ylmethyl)ethanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1773181; BDBM50343148; MCULE-8576155103
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-(3-Bromoanilino)-5-hydroxybenzothiazole-6-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3596431; BDBM50498446
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| Activity |
IC50 = 50000 nM
|
[3] | |||
| Compound Name |
(S)-2-(4-(Benzamidomethyl)-1H-1,2,3-triazol-1-yl)-3-(4-hydroxyphenyl)propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1667962; BDBM50336334
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
Triazole tetra-benzyloxy-beta-D-O-glucosyl Threonine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1667954; BDBM50336336
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
Triazole tetra-benzyloxy-beta-D-O-glucosyl Serine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1667953; BDBM50336335
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
Triazole tetra-benzyloxy-beta-D-O-glucosyl Tyrosine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1667956; BDBM50336338
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(S)-3-Hydroxy-2-(4-(((2R,3R,4S,5S,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yloxy)methyl)-1H-1,2,3-triazol-1-yl)propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1667955; BDBM50336337
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
3,4,6-Tribromo-5-[(2,3,6-tribromo-4,5-dihydroxyphenyl)methyl]benzene-1,2-diol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL374829; BDBM50363494; 5,5'-Methylenebis(3,4,6-tribromocatechol); bis(2,3,6-tribromo-4,5-dihydroxyphenyl)methane
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
N-(4-Butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1773168; Oprea1_072325; Oprea1_160592; ZINC2184757; BDBM50343142; STL224021; AKOS002276777; MCULE-2878647302; ST45174155; AQ-390/10779040; SR-01000481320; SR-01000481320-1; F0884-0032
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
N-(2-Furylmethyl)-N'-{2-[4-(4-methoxyphenyl)piperazin-1-yl]-1-methyl-2-thien-2-ylethyl}ethanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1773180; BDBM50343147; MCULE-6096211710
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
Methyl (2S)-2-[4-(benzamidomethyl)triazol-1-yl]-3-(4-hydroxyphenyl)propanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1667961; BDBM50336333; (S)-2-(4-(benzamidomethyl)-1H-1,2,3-triazol-1-yl)-3-(4-hydroxyphenyl)propanoate methyl ester
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
N,N'-4,4'-Biphenyldiyldi(2-furamide)
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Investigative | Compound Info | ||
| Synonyms |
Oprea1_382357; Oprea1_520693; CBDivE_000591; ARONIS003800; CHEMBL3238181; KS-00003WPS; BDBM124233; ZINC652081; STK013403; AKOS000493481; MCULE-7796221608; ST031916; N,N'-biphenyl-4,4'-diyldifuran-2-carboxamide; AH-034/07271034; N-[4'-(2-furoylamino)[1,1'-biphenyl]-4-yl]-2-furamide; 2-furyl-N-{4-[4-(2-furylcarbonylamino)phenyl]phenyl}carboxamide
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| Activity |
IC50 = 52070 nM
|
[6] | |||
| Compound Name |
2-Hydroxy-5-[4-[4-[[(2R,3R,4S,5R,6S)-3,4,5-tribenzoyloxy-6-methoxyoxan-2-yl]methoxymethyl]triazol-1-yl]butoxy]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1822606; BDBM50351998
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| Activity |
IC50 = 54300 nM
|
[7] | |||
| Compound Name |
(2E,5E)-5-[(4-Chlorophenyl)methylidene]-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
Thiazole analogue, 6; thiazolidinone derivative, 6; CHEMBL271751; BDBM22341; BDBM24519; (5E)-5-[(4-chlorophenyl)methylidene]-2-(1,3-thiazol-2-ylamino)-4,5-dihydro-1,3-thiazol-4-one
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| Activity |
Ki = 54500 nM
|
[8] | |||
| Compound Name |
2-[3-(3-Carboxypropanoylamino)phenyl]-6-hydroxy-3-iodo-1-methylindole-5-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3319382; SCHEMBL17669852; BDBM50054263; IC=1C2=CC(C(O)=O)=C(O)C=C2N(C)C=1C1=CC=CC(NC(=O)CCC(O)=O)=C1
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| Activity |
IC50 = 56000 nM
|
[9] | |||
| Compound Name |
3-[(3-Nitrophenyl)diazenyl]-1H-indol-2-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL521563; BDBM152150; US8987474, HL1-050-2
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| Activity |
IC50 ~ 60000 nM
|
[10] | |||
| Compound Name |
2-[2-(2-Oxoindol-3-yl)hydrazinyl]benzoic Acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL498479; SCHEMBL4408112; HMS1743J14; ZINC7735532; AKOS002079391; MCULE-4926369038; Z86109290; 2-[(2E)-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]benzoic acid; 2-[2-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)hydrazin-1-yl]benzoic acid
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| Activity |
IC50 ~ 60000 nM
|
[10] | |||
| Compound Name |
3-[2-(2-Nitrophenyl)hydrazinyl]indol-2-one
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Investigative | Compound Info | ||
| Synonyms |
3-[(2-nitrophenyl)hydrazono]-1,3-dihydro-2H-indol-2-one; NSC111581; CHEMBL498650; SCHEMBL9661852; DTXSID50419042; isatin 3-(o-nitrophenylhydrazone); BDBM152148; ZINC5093001; AKOS001046101; AKOS030656653; MCULE-4574516522; NSC-111581; Indole-2, 3-[(o-nitrophenyl)hydrazone]; NCI60_000259; DS-002930; 1H-Indole-2, 3-[(2-nitrophenyl)hydrazone]; US8987474, HL1-047; 1H-Indole-2,3-dione, 3-[(2-nitrophenyl)hydrazone]
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| Activity |
IC50 ~ 60000 nM
|
[10] | |||
| Compound Name |
3-[2-(2-Oxoindol-3-yl)hydrazinyl]benzoic Acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL498475; SCHEMBL4408992; CTK7H5913; ZINC6673754; STK398283; AKOS000313005; AKOS002527099; MCULE-1745107261; 3-[(2Z)-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinyl]benzoic acid; 3-[(2Z)-2-(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)HYDRAZINO]BENZOIC ACID
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| Activity |
IC50 ~ 60000 nM
|
[10] | |||
| Compound Name |
[(4-{2-[4-(Difluoro-phosphono-methyl)-benzyloxy]-phenoxymethyl}-phenyl)-difluoro-methyl]-phosphonic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL337604; BDBM50107744; [o-Phenylenebis[(oxymethylene-p-phenylene)(difluoromethylene)]]bis(phosphonic acid)
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| Activity |
IC50 = 60000 nM
|
[11] | |||
| Compound Name |
Ethyl 2-[[5-[4-(3-chlorophenyl)piperazin-1-yl]sulfonyl-2,3-dihydroindole-1-carbonyl]amino]acetate
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL2278631; CHEMBL3693936; BDBM111889; US8623906, JHE-01-134A
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| Activity |
IC50 = 60300 nM
|
[12] | |||
| Compound Name |
3-[2-(2,4-Dichlorophenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4907223; CHEMBL3692079; SCHEMBL14111914; BDBM152102; US8987474, RPM224
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm332
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4896236; CHEMBL3696151; BDBM152196; 3-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]-N-(pyridin-3-ylmethyl)benzamide
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
3-[2-(2-Ethylphenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4898165; CHEMBL3692072; SCHEMBL14111910; BDBM152095; US8987474, RPM219
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm191
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4904428; CHEMBL3692082; BDBM152106
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
3-[2-(2,5-Dichlorophenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4904916; CHEMBL3692080; SCHEMBL14111915; BDBM152103; US8987474, RPM225
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm290
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4906448; CHEMBL3696135; BDBM152177; 2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]-N-(pyridin-3-ylmethyl)benzamide
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
3-(1,3-Benzothiazol-2-yldiazenyl)-2-hydroxy-1H-indole-5-sulfonic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692121; SCHEMBL14111952; BDBM152154; US8987474, HL1-058-3
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
3-[[2-Oxo-5-(propan-2-ylsulfamoyl)-1H-indol-3-ylidene]methylamino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4896066; CHEMBL3696142; BDBM152186; US8987474, RPM304
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm202
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692061; SCHEMBL14111896; BDBM152084
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
2-[2-(2-Oxo-5-sulfoindol-3-yl)hydrazinyl]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4904786; CHEMBL3692081; BDBM152105; US8987474, RPM211
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
2-[(5-Isopropylsulfamoyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)amino]benzoic acid methyl ester
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4901274; CHEMBL3696154; BDBM152199; US8987474, RPM335; methyl 2-[[2-oxo-5-(propan-2-ylsulfamoyl)-1H-indol-3-ylidene]methylamino]benzoate
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-1H-indole-5-sulfonic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692119; SCHEMBL14111951; BDBM152152; US8987474, HL1-058-1
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
Indole-2, 3-[(o-chlorophenyl)hydrazone]
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Investigative | Compound Info | ||
| Synonyms |
MLS002701969; NSC117192; CHEMBL1652341; CHEMBL1725934; SCHEMBL14111949; DTXSID10419088; BDBM152149; ZINC102824210; NSC-117192; NCI60_000401; SMR001565547; US8987474, HL1-050-1
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
Ethyl 3-[[2-oxo-5-(propan-2-ylsulfamoyl)-1H-indol-3-ylidene]methylamino]benzoate
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4909442; CHEMBL3696140; BDBM152184; US8987474, RPM302
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
US8987474, HL2-026-Intermediate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692068; SCHEMBL14111906; BDBM152091
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
2-[(5-Isopropylsulfamoyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)amino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4896107; CHEMBL3696155; BDBM152200; US8987474, RPM336; 2-[[2-oxo-5-(propan-2-ylsulfamoyl)-1H-indol-3-ylidene]methylamino]benzoic acid
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm333
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL5322045; CHEMBL3696152; SCHEMBL14111860; BDBM152197
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
2-Hydroxy-3-[(3-nitrophenyl)diazenyl]-1H-indole-5-sulfonic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692120; BDBM152153; US8987474, HL1-058-2
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
4-[[2-Oxo-5-(propan-2-ylsulfamoyl)-1H-indol-3-ylidene]methylamino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4904801; CHEMBL3696143; BDBM152187; US8987474, RPM305
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
2-Oxo-3-[2-(2,3,4,5,6-pentafluorophenyl)hydrazinyl]indole-5-sulfonic acid
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4896235; CHEMBL3692076; BDBM152099; US8987474, RPM222
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
3-(2-Naphthalen-1-ylhydrazinyl)-2-oxoindole-5-sulfonic acid
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4909412; CHEMBL3639909; BDBM152104; US8987474, RPM223
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
3-[2-[2-Oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4896245; CHEMBL3696146; BDBM152190; US8987474, RPM325
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm270
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4939902; CHEMBL3696157; BDBM152202
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
N,N-Dimethyl-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4414149; CHEMBL3692083; BDBM152108; US8987474, RPM124
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|
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm204
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692062; SCHEMBL14111898; BDBM152085
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|
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm292
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696136; SCHEMBL14111974; BDBM152178; N-(furan-2-ylmethyl)-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
2-Oxo-3-[2-[2-(trifluoromethyl)phenyl]hydrazinyl]indole-5-sulfonic acid
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4901352; CHEMBL3692074; SCHEMBL14111912; BDBM152097; US8987474, RPM221
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
3-[2-(2,6-Dichlorophenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4908771; CHEMBL3692078; SCHEMBL14111913; BDBM152101; US8987474, RPM218
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|
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
3-[2-(2-Nitrophenyl)hydrazinyl]-2-oxo-N-(pyridin-2-ylmethyl)indole-5-sulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692100; SCHEMBL14111840; BDBM152125; US8987474, RPM135
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| Activity |
IC50 = 66500 nM
|
[13] | |||
| Compound Name |
6-Hydroxy-1-methyl-3-(1-(3-oxo-3-(phenylamino)propyl)-1H-1,2,3-triazol-4-yl)-2-phenyl-1H-indole-5-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL605541; BDBM50308166
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||||
| Activity |
IC50 = 86000 nM
|
[14] | |||
| Compound Name |
(2Z,5E)-2-(1,2-Benzothiazol-3-ylimino)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Benzisothiazole analogue, 17; CHEMBL527428; BDBM24530
Click to Show/Hide
|
||||
| Activity |
Ki = 90800 nM
|
[8] | |||
| Compound Name |
[(4-{4-[4-(Difluoro-phosphono-methyl)-phenyl]-butyl}-phenyl)-difluoro-methyl]-phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4316970; CHEMBL1161222; DB04204; Q27095031; Tetramethylenebis[(p-phenylene)(difluoromethylene)]bis(phosphonic acid); {butane-1,4-diylbis[benzene-4,1-diyl(difluoromethanediyl)]}bis(phosphonic acid)
Click to Show/Hide
|
||||
| Activity |
IC50 = 91000 nM
|
[11] | |||
| Compound Name |
N-[(3-Methoxyphenyl)methyl]-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4907827; CHEMBL3692096; BDBM152121; US8987474, RPM137
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-Oxo-3-(2-phenylhydrazinyl)indole-5-sulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4907090; CHEMBL3692075; BDBM152098; US8987474, RPM215
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(2S,3S)-2-[[(3S,6S,9S,12S,15S)-3-Benzyl-12-[(2S)-butan-2-yl]-6-(1H-indol-3-ylmethyl)-7-methyl-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentazacyclononadec-15-yl]carbamoylamino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL409618; BDBM50192335
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
6-[(3-Sulfophenyl)carbamoyl]naphthalene-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692067; SCHEMBL14111904; BDBM152090; US8987474, HL2-022-2
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(pyridin-4-ylmethyl)-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692115; SCHEMBL14111941; BDBM152141; US8987474, HL2-016-15
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
5-[(6-Carboxynaphthalene-2-carbonyl)amino]benzene-1,3-dicarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692069; SCHEMBL14111907; BDBM152092; US8987474, HL2-026
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[2-(2-Nitrophenyl)hydrazinyl]-2-oxo-N-propylindole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4901212; CHEMBL3692089; BDBM152114; US8987474, RPM170
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm310
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696145; SCHEMBL14111886; BDBM152189
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-(2-Methoxyethyl)-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4908586; CHEMBL3696132; BDBM152174; US8987474, RPM285
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-Benzyl-N-methyl-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4903811; CHEMBL3692098; BDBM152123; US8987474, RPM136
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[2-[2-Oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4907302; CHEMBL3696130; BDBM152172; US8987474, RPM283
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(2S)-2-[[(2S,3S)-2-[[(2S)-4-Carboxy-2-[[(2S)-4-carboxy-2-[[2-phenyl-3-(4-phosphonooxyphenyl)propanoyl]amino]butanoyl]amino]butanoyl]amino]-3-methylpentanoyl]amino]pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2092743; BDBM50403558
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-Benzyl-3-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4904487; CHEMBL3696148; BDBM152193; US8987474, RPM328
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Nitroanilino)methylidene]-2-oxo-N-propan-2-yl-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4895068; SCHEMBL4895069; CHEMBL3696141; SCHEMBL14111883; BDBM152185; US8987474, RPM303
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[2-(2-Methylphenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4907899; CHEMBL3692071; SCHEMBL14111909; BDBM152094; US8987474, RPM216
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm195
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692060; SCHEMBL14111895; BDBM152083
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-N-(furan-2-ylmethyl)-2-hydroxy-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692111; SCHEMBL14111933; BDBM152137; US8987474, HL2-016-11
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-{2-[(3Z)-5-{[(4-Chlorophenyl)methyl]carbamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oxindole scaffold, 16; CHEMBL497510; SCHEMBL4412396; BDBM24535; BDBM152167; BDBM152170; US8987474, HL2-070-5; US8987474, HL2-070-9; 3-[2-[5-[(4-chlorophenyl)methylcarbamoyl]-2-oxoindol-3-yl]hydrazinyl]benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-Methyl-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4903838; CHEMBL3696139; BDBM152181; US8987474, RPM295
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(2-methylpropyl)-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692110; SCHEMBL14111932; BDBM152136; US8987474, HL2-016-10
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-[(3-methoxyphenyl)methyl]-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692105; SCHEMBL14111927; BDBM152131; US8987474, HL2-016-5
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-methylpentanoyl]amino]pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328907; BDBM50450413; ZINC95606311
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Ethyl 4-[[2-oxo-5-(propan-2-ylsulfamoyl)-1H-indol-3-ylidene]methylamino]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4904420; CHEMBL3696134; BDBM152176; US8987474, RPM288
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm284
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4909381; CHEMBL3696131; BDBM152173; N-[2-(dimethylamino)ethyl]-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm177
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4924995; CHEMBL3692087; BDBM152112
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[2-(2-Oxo-5-sulfamoylindol-3-yl)hydrazinyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4896039; CHEMBL3692070; BDBM152093; US8987474, RPM188
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm185
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692063; SCHEMBL14111897; BDBM152086
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm156
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4935561; CHEMBL3692086; BDBM152111
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm319
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696164; SCHEMBL14111992; BDBM152209
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-Benzyl-3-[(2-chlorophenyl)diazenyl]-2-hydroxy-N-methyl-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692116; SCHEMBL14111942; BDBM152142; US8987474, HL2-016-16
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm293
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4907091; CHEMBL3696137; BDBM152179; N-(2-morpholin-4-ylethyl)-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2,2,6,6-Tetramethyl-N-(4-phenyl-1,3-thiazol-2-yl)piperidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4088271; BDBM50250916; ZINC12975547; AKOS034028260; MCULE-2242908225; Z278099856
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N,N-dimethyl-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692101; SCHEMBL14111922; BDBM152127; US8987474, HL2-016-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[2-(2-Nitrophenyl)hydrazinyl]-2-oxo-N-(oxolan-2-ylmethyl)indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692093; SCHEMBL14111858; BDBM152118; US8987474, RPM172
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-Oxo-3-(2-phenylhydrazinyl)indole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4895008; CHEMBL3696159; BDBM152204; US8987474, RPM272
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-(2-Methoxyethyl)-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692091; SCHEMBL14111856; BDBM152116; US8987474, RPM171
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N,N-Diethyl-2-hydroxy-3-[(2-nitrophenyl)diazenyl]-1H-indole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696125; SCHEMBL14111964; BDBM152165; US8987474, HL2-070-3
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(pyridin-2-ylmethyl)-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692107; SCHEMBL14111929; BDBM152133; US8987474, HL2-016-7
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(2S,3S)-2-[[(3S,6R,9S,12S,15S)-3-Benzyl-6-[2-[2-(carbamoylamino)phenyl]-2-oxoethyl]-7-methyl-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-12-propan-2-yl-1,4,7,10,13-pentazacyclononadec-15-yl]carbamoylamino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL439324; BDBM50192337
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(pyridin-3-ylmethyl)-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692117; SCHEMBL14111944; BDBM152143; US8987474, HL2-016-18
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-[(4-Chlorophenyl)methyl]-2-oxo-1,3-dihydroindole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4907229; CHEMBL3696144; BDBM152188; US8987474, RPM307
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(oxolan-2-ylmethyl)-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692114; SCHEMBL14111940; BDBM152140; US8987474, HL2-016-14
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(2S,3S)-2-[[(3S,6S,9S,12S,15S)-3-Benzyl-6-(1H-indol-3-ylmethyl)-7-methyl-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-12-propan-2-yl-1,4,7,10,13-pentazacyclononadec-15-yl]carbamoylamino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL377360; Brunsvicamide A; BDBM50192336
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
2-Hydroxy-3-[(2-nitrophenyl)diazenyl]-N-(pyridin-3-ylmethyl)-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692118; SCHEMBL14111945; BDBM152145; US8987474, HL2-016-20
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[2-(2-Nitrophenyl)hydrazinyl]-2-oxo-N-(pyridin-4-ylmethyl)indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692099; SCHEMBL14111847; BDBM152124; US8987474, RPM145
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
1-Ethyl-N,N-dimethyl-3-[(2-nitrophenyl)hydrazinylidene]-2-oxoindole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4909361; CHEMBL3692085; BDBM152110; US8987474, RPM176
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-Hydroxy-3-[(2-nitrophenyl)diazenyl]-1H-indole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696122; SCHEMBL14111961; BDBM152162; US8987474, HL2-05432
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
6-(Phenylcarbamoyl)naphthalene-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945663; SCHEMBL14111908; BDBM50363673
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
6-Hydroxy-3-(3-hydroxyprop-1-ynyl)-2-phenyl-benzofuran-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2316900; BDBM50425821
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(morpholin-4-ylmethyl)-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692108; SCHEMBL14111930; BDBM152134; US8987474, HL2-016-8
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[2-(2-Fluorophenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4903322; CHEMBL3692073; SCHEMBL14111911; BDBM152096; US8987474, RPM220
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-[2-(Dimethylamino)ethyl]-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692088; SCHEMBL14111849; BDBM152113; US8987474, RPM146
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-N-[(4-chlorophenyl)methyl]-2-hydroxy-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692104; SCHEMBL14111926; BDBM152130; US8987474, HL2-016-4
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[[2-Hydroxy-5-(propan-2-ylcarbamoyl)-1H-indol-3-yl]diazenyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696128; SCHEMBL14111968; BDBM152169; US8987474, HL2-070-7
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(thiophen-2-ylmethyl)-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692106; SCHEMBL14111928; BDBM152132; US8987474, HL2-016-6
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-Ethyl-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4908777; CHEMBL3639950; BDBM152182; US8987474, RPM296
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[[5-(Diethylcarbamoyl)-2-hydroxy-1H-indol-3-yl]diazenyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696123; SCHEMBL14111962; BDBM152163; US8987474, HL2-070-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-[(4-methoxyphenyl)methyl]-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692103; SCHEMBL14111925; BDBM152129; US8987474, HL2-016-3
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[2-(2-Nitrophenyl)hydrazinyl]-2-oxo-N-(thiophen-2-ylmethyl)indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692095; SCHEMBL14111845; BDBM152120; US8987474, RPM140
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N,N-Dimethyl-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4904943; CHEMBL3696138; BDBM152180; US8987474, RPM294
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-Benzoyl-1H-indole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4907100; CHEMBL3696162; BDBM152207; US8987474, RPM352
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
6-[(3-Carboxyphenyl)carbamoyl]naphthalene-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692066; SCHEMBL14111903; BDBM152089; US8987474, HL2-022-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[[5-(Diethylcarbamoyl)-2-hydroxy-1H-indol-3-yl]diazenyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696124; SCHEMBL14111963; BDBM152164; US8987474, HL2-070-2
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-[(4-Methoxyphenyl)methyl]-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4907197; CHEMBL3692097; BDBM152122; US8987474, RPM138
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-(Furan-2-ylmethyl)-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692094; SCHEMBL14111853; BDBM152119; US8987474, RPM168; 3-[(2-Nitrophenyl)hydrazono]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (furan-2-ylmethyl)amide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm347
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4904788; CHEMBL3696156; BDBM152201
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-Butan-2-yl-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4909460; CHEMBL3692092; BDBM152117; US8987474, RPM173
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[[5-[(4-Chlorophenyl)methylcarbamoyl]-2-hydroxy-1H-indol-3-yl]diazenyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696126; SCHEMBL14111966; BDBM152166; US8987474, HL2-070-4
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm187
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692059; SCHEMBL14111894; BDBM152082
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-Benzoyl-1H-indole-5-carboxylic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4907150; CHEMBL3696163; BDBM152208; US8987474, RPM341; methyl 3-benzoyl-1H-indole-5-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm351
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696160; SCHEMBL14111893; BDBM152205
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-Benzyl-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4906515; CHEMBL3696133; BDBM152175; US8987474, RPM287
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm154
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4938452; CHEMBL3692084; BDBM152109
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-Butan-2-yl-3-[(2-chlorophenyl)diazenyl]-2-hydroxy-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692113; SCHEMBL14111938; BDBM152139; US8987474, HL2-016-13
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-Methyl-3-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4900103; CHEMBL3696149; BDBM152194; US8987474, RPM330
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm194
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692064; SCHEMBL14111900; BDBM152087
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-Oxo-3-(2-phenylhydrazinyl)-N-propan-2-ylindole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4904442; CHEMBL3696129; BDBM152171; US8987474, RPM275
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-Ethyl-3-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4903236; CHEMBL3696150; BDBM152195; US8987474, RPM331
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-propyl-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692109; SCHEMBL14111931; BDBM152135; US8987474, HL2-016-9
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692102; SCHEMBL14111924; BDBM152128; US8987474, HL2-016.2
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(2-methoxyethyl)-1H-indole-5-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692112; SCHEMBL14111939; BDBM152138; US8987474, HL2-016-12
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[[2-Hydroxy-5-(propan-2-ylcarbamoyl)-1H-indol-3-yl]diazenyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696127; SCHEMBL14111967; BDBM152168; US8987474, HL2-070-6
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm334
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4907140; CHEMBL3696153; BDBM152198; N-(2-morpholin-4-ylethyl)-3-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-[2-(2-Ethylphenyl)hydrazinyl]-2-oxoindole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4898063; CHEMBL3696158; BDBM152203; US8987474, RPM320
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, HL2-022-1-Intermediate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3692065; SCHEMBL14111901; BDBM152088
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
US8987474, Rpm350
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3696161; SCHEMBL14111892; BDBM152206
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(2E,5E)-5-[(4-Hydroxy-3-methoxyphenyl)methylidene]-2-[(4-phenyl-1,3-thiazol-2-yl)imino]-1,3-thiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Thiazole analogue, 9; CHEMBL519399; BDBM24522
Click to Show/Hide
|
||||
| Activity |
Ki = 103200 nM
|
[8] | |||
| Compound Name |
3-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)naphthalen-2-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3910462
Click to Show/Hide
|
||||
| Activity |
IC50 = 114800 nM
|
[19] | |||
| Compound Name |
5-(1H-Indol-3-ylmethyl)-3-[6-(3-methylphenyl)pyridin-2-yl]-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3759827; BDBM50142962
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
3-[6-(4-Ethoxyphenyl)pyridin-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3759234; BDBM50142960
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
5-(1H-Indol-3-ylmethyl)-3-[3-(4-propoxyphenyl)phenyl]-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3759036; BDBM50142938
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
4-[3-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3759694; BDBM50143014
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
5-(1H-Indol-3-ylmethyl)-3-[5-(3-methylphenyl)thiophen-2-yl]-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3759157; BDBM50142969
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
5-(1H-Indol-3-ylmethyl)-3-[5-(4-propylphenyl)thiophen-2-yl]-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3758655; BDBM50142975
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
(2S)-3-[[1-[[(2R,3S,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1795946; BDBM50347241
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[20] | |||
| Compound Name |
5-(1H-Indol-3-ylmethyl)-3-[3-(4-propylphenyl)phenyl]-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3760020; BDBM50143001
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
3-(3-Bromophenyl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3758567; BDBM50142957
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
5-(1H-Indol-3-ylmethyl)-3-[5-(4-propoxyphenyl)thiophen-2-yl]-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3759712; BDBM50142985
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
4-[5-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]thiophen-2-yl]aniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3357362; BDBM50142941
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
4-[3-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]aniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3357363; BDBM50142993
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
(2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[[1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]triazol-4-yl]methoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1795952; BDBM50347245
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[20] | |||
| Compound Name |
(2S)-3-[[1-[[(2R,3R,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1795944; BDBM50347239
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[20] | |||
| Compound Name |
3-(5-Bromothiophen-2-yl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3758203; BDBM50142958
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
5-(1H-Indol-3-ylmethyl)-3-[6-(2-methylphenyl)pyridin-2-yl]-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3760029; BDBM50142963
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
(2S,3S)-3-[[1-[[(2R,3S,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1795947; BDBM50347246
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[20] | |||
| Compound Name |
3-[5-(4-Ethylphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3758844; BDBM50142972
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
3-(6-Bromopyridin-2-yl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3759431; BDBM50142947
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
Methyl 4-[4-[5-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]thiophen-2-yl]phenoxy]butanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3758785; BDBM50143010
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
3-[5-(4-Ethoxyphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3759414; BDBM50142979
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
4-[6-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]pyridin-2-yl]phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3758876; BDBM50142940
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
3-[3-(4-Ethoxyphenyl)phenyl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3758728; BDBM50143004
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
Methyl 4-[4-[3-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]phenoxy]butanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3760059; BDBM50142939
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
5-(1H-Indol-3-ylmethyl)-3-[3-(3-methylphenyl)phenyl]-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3759304; BDBM50142999
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
3-[5-(4-Butylphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3758490; BDBM50142976
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
3-[3-(4-Butylphenyl)phenyl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3760096; BDBM50143002
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
(2S,3S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[[1-[(2R,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]triazol-4-yl]methoxy]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1795951; BDBM50347244
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[20] | |||
| Compound Name |
5-(1H-Indol-3-ylmethyl)-3-[3-(2-methylphenyl)phenyl]-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3759130; BDBM50142995
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
3-[6-(4-Butylphenyl)pyridin-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3758715; BDBM50142961
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
5-(1H-Indol-3-ylmethyl)-3-[6-(4-propoxyphenyl)pyridin-2-yl]-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3759405; BDBM50142959
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
(2S)-3-[[1-[[(2R,3R,4S,5S,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1795948; BDBM50347247
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[20] | |||
| Compound Name |
5-(1H-Indol-3-ylmethyl)-3-[5-(2-methylphenyl)thiophen-2-yl]-1,2,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3758446; BDBM50142967
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[1] | |||
| Compound Name |
(2S,3S)-3-[[1-[[(2R,3R,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1795945; BDBM50347240
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[20] | |||
| Compound Name |
(2S,3S)-3-[[1-[[(2R,3R,4S,5S,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1795949; BDBM50347242
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 120000 nM
|
[20] | |||
| Compound Name |
2-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-6-phenylphenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3938397
Click to Show/Hide
|
||||
| Activity |
IC50 = 136000 nM
|
[19] | |||
| Compound Name |
4-[5-[4-(2,3-Dichlorophenyl)piperazin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]-4-oxobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL2278539; CHEMBL3693937; BDBM111890; US8623906, XW2-038G
Click to Show/Hide
|
||||
| Activity |
IC50 = 143600 nM
|
[12] | |||
| Compound Name |
Azane;[[4-[2-[[4-[difluoro(phosphono)methyl]phenyl]methoxy]ethoxymethyl]phenyl]-difluoromethyl]phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL344437
Click to Show/Hide
|
||||
| Activity |
IC50 = 152000 nM
|
[11] | |||
| Compound Name |
3-[(3-Acetyl-2-methyl-1-benzofuran-5-yl)sulfamoyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
GNF-Pf-1973; CHEMBL579363; SCHEMBL19057890; ZINC4817936; BDBM50348091; AKOS000594229; MCULE-9659738949; SR-01000492177; SR-01000492177-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 176000 nM
|
[21] | |||
| Compound Name |
4-[Acetyl(6,7,8,9-tetrahydrodibenzofuran-2-yl)sulfamoyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800272; ZINC5047504; BDBM50348090; MCULE-6656366858; SR-01000285894; SR-01000285894-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 181000 nM
|
[21] | |||
| Compound Name |
Sodium;(2S)-2-[[[ethoxy(hydroxy)phosphoryl]-(2-hydroxyphenyl)methyl]amino]-3-hydroxypropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946248
Click to Show/Hide
|
||||
| Activity |
IC50 = 191000 nM
|
[22] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 31 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Estramustine
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
Estramustina; Estramustinum; Emcyt (TN); Estramustine (USAN/INN); Estradiol 3-[bis(2-chloroethyl)carbamate]; Ro-22-2296/000; Estra-1,3,5(10)-triene-3,17-diol (17.beta.)-, 3-[bis(2-chloroethyl)carbamate]; [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] N,N-bis(2-chloroethyl)carbamate; (17beta)-17-hydroxyestra-1(10),2,4-trien-3-yl bis(2-chloroethyl)carbamate; 17.beta.-Estradiol 3-[bis(2-chloroethyl)carbamate]
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[23] | |||
| Compound Name |
Estradiol
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
Aerodiol; Alora; Altrad; Aquadiol; Bardiol; Climaderm; Climara; Compudose; Corpagen; Dermestril; Destradiol; Dihydrofolliculin; Dihydromenformon; Dihydrotheelin; Dihydroxyesterin; Dihydroxyestrin; Dihydroxyoestrin; Dimenformon; Diogyn; Diogynets; Divigel; Elestrin; Encore; Esclim; Estrace; Estraderm; Estradiolo; Estradiolum; Estradot; Estraldine; Estrasorb; Estreva; Estrifam; Estring; Estroclim; Estrodiolum; Estrogel; Estrovite; Evamist; Evorel; Extrasorb; Femanest; Femestral; Femestrol; Fempatch; Femtran; Follicyclin; Gelestra; Ginedisc; Ginosedol; GynPolar; Gynergon; Gynestrel; Gynodiol; Gynoestryl; Innofem; Lamdiol; Macrodiol; Macrol; Menest; Menorest; Microdiol; Nordicol; Oesclim; Oestergon; Oestradiol; Oestradiolum; Oestrogel; Oestroglandol; Oestrogynal; Ovahormon; Ovasterol; Ovastevol; Ovociclina; Ovocyclin; Ovocycline; Ovocylin; Perlatanol; Polyestradiol; Primofol; Profoliol; Progynon; Syndiol; Systen; Tradelia; Trocosone; Vagifem; Vivelle; Zerella; Zesteem; Zesteen; Zumenon; Climara Forte; Component of Menrium; Estraderm MX; Estraderm TTS; Estradiolo [DCIT]; Estradiolum [INN]; Estring vaginal ring; Estrofem Forte; Oestradiol Berco; Oestradiol R; Progynon DH; Sandrena Gel; Sisare Gel; Trial SAT; CMC_11154; Compudose 200; Compudose 365; E 2; E 8875; E0025; Epiestriol 50; Estraderm TTS 100; Estraderm TTS 50; Estrapak 50; Estroclim 50; Estrofem 2; Sandrena 1; [3H]]estradiol; Activella (TN); Alora (TN); Alpha-Oestradiol; AngeliQ (TN); B-Estradiol; Beta-Estradiol; Beta-Oestradiol; Beta-estradiol; Cis-Estradiol; Cis-Oestradiol; Climara (TN); D-Estradiol; D-Oestradiol; Divigel (TN); E(sub 2); Elestrin (TN); Estrace (TN); Estraderm (TN); Estraderm TTS (TN); Estradiol [USAN:INN]; Estradiol acetate (TN); Estradiol cypionate (TN); Estradiol valerate (TN); Estradiol-17 beta; Estradiol-17beta; Estrasorb (TN); Estrasorb Topical (TN); Estring (TN); Estrofem (TN); Estrogel (TN); EvaMist (TN); Femring (TN); Innofem (TN); Menostar (TN); Oestradiol-17beta; Progynon-DH; Progynova (TN); S-21400; SK-Estrogens; SL-1100; VIVELLE-DOT; Vagifem (TN); Vivelle (TN); [3H]-estradiol; Estradiol-17-beta; Estradiol-3,17beta; Oestradiol-17-beta; Vivelle-Dot (TN); D-3,17beta-Estradiol; [2,4,6,7-3H]-E2; 17 beta-Estradiol; 17-.BETA.-Estradiol; 17-beta-OH-estradiol; 17-beta-estradiol; 17.beta.-Estradiol; 17.beta.-Oestradiol; 17b-Oestradiol; 17beta oestradiol; 17beta-Estradiol; 17beta-Oestradiol; 3,17-beta-Estradiol; 3,17-beta-Oestradiol; 3,17.beta.-Estradiol; 3,17beta-Estradiol
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[23] | |||
| Compound Name |
2-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-4-methylphenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3928298; SCHEMBL17286687
Click to Show/Hide
|
||||
| Activity |
IC50 = 201800 nM
|
[19] | |||
| Compound Name |
Sodium;(2S)-2-[[[ethoxy(hydroxy)phosphoryl]-(2-hydroxyphenyl)methyl]amino]-3-(1H-imidazol-5-yl)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946249
Click to Show/Hide
|
||||
| Activity |
IC50 = 210000 nM
|
[22] | |||
| Compound Name |
3-Ethynyl-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL603136; BDBM50308163; 3-ethynyl-6-hydroxy-1-methyl-2-phenylindole-5-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 212000 nM
|
[14] | |||
| Compound Name |
(6R,8'R,9'S,13'S,14'S)-N,N-Bis(2-chloroethyl)-3'-methoxy-13'-methyl-2-oxospiro[1,3,2lambda5-oxazaphosphinane-6,17'-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene]-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1642764; NSC-233064; BDBM50333648
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[23] | |||
| Compound Name |
(2E,5E)-5-[(4-Hydroxyphenyl)methylidene]-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Thiazole analogue, 1; thiazolidinone derivative, 1; CHEMBL259672; BDBM22335; BDBM24513; (5E)-5-[(4-hydroxyphenyl)methylidene]-2-(1,3-thiazol-2-ylamino)-4,5-dihydro-1,3-thiazol-4-one
Click to Show/Hide
|
||||
| Activity |
Ki = 388000 nM
|
[8] | |||
| Compound Name |
2-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-4-phenylphenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3929350
Click to Show/Hide
|
||||
| Activity |
IC50 = 392200 nM
|
[19] | |||
| Compound Name |
(2E,5E)-5-[(4-Nitrophenyl)methylidene]-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Thiazole analogue, 4; thiazolidinone derivative, 4; CHEMBL407592; BDBM22339; BDBM24517; (5E)-5-[(4-nitrophenyl)methylidene]-2-(1,3-thiazol-2-ylamino)-4,5-dihydro-1,3-thiazol-4-one
Click to Show/Hide
|
||||
| Activity |
Ki = 473600 nM
|
[8] | |||
| Compound Name |
{3(S)-Methylcarbamoyl-2-[3-(3-sulfoamino-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinolin-7-YL}-sulfamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL204337; SCHEMBL6393262; BDBM13461; ZINC14952759; Tetrahydroisoquinoline (TIQ) deriv. 10i; Q27466911
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[24] | |||
| Compound Name |
2-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-5-phenylphenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3901405
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[19] | |||
| Compound Name |
2-(2-Hydroxy-1,1,1,3,3,3-hexafluoropropyl)-1-naphthol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)naphthalen-1-ol; SCHEMBL589730; CHEMBL3911513; CTK4E5485; DTXSID10379370; ZINC4348173; 7113AD; MFCD06247736; AKOS015856309; DB-045436; 2-(2-Hydroxyhexafluoroisopropyl)naphth-1-ol; FT-0634033; J-013725; 2-Naphthalenemethanol,1-hydroxy-a,a-bis(trifluoromethyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[19] | |||
| Compound Name |
(2E)-3-[3-Chloro-4-(4-fluorophenyl)phenyl]prop-2-enoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-Cl-AHPC analogue, 5; CHEMBL459710; BDBM25126
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[25] | |||
| Compound Name |
1,1,1,3,3,3-Hexafluoro-2-phenylpropan-2-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol; (Hexafluoro-2-hydroxyisopropyl)benzene; Benzenemethanol, .alpha.,.alpha.-bis(trifluoromethyl)-; alpha,alpha-Bis(trifluoromethyl)benzyl alcohol; 2,2,2,2',2',2'-Hexafluorocumyl alcohol; hexafluoro-2-phenylisopropanol; Hexafluoro-2-phenyl isopropanol; Hexafluoro-2-phenyl-2-propanol; Benzenemethanol, alpha,alpha-bis(trifluoromethyl)-; MFCD00040983; Bis(trifluoromethyl)phenylcarbinol; EINECS 211-943-4; A,A-Bis(trifluoromethyl)benzyl alcohol; ACMC-209okf; SCHEMBL542694; Hexafluoro-2-phenylpropan-2-ol; CHEMBL3955910; DTXSID3061051; CTK2H8729; IZPIZCAYJQCTNG-UHFFFAOYSA-; ZINC157910; 2-hydroxy-2-phenylhexafluoropropane; KS-000016YZ; NSC96337; 1158AC; ANW-36109; NSC-96337; SBB099807; AKOS003619425; MCULE-2651808885; 2,2,2,2,2,2-Hexafluorocumyl Alcohol; 2,2,2,2,2,2,-hexafluorocumyl alcohol; AS-48861; DB-055578; alpha,alpha-Di(trifluoromethyl)benzyl alcohol; Benzyl alcohol,.alpha.-bis(trifluoromethyl)-; FT-0604631; ST51007775; Benzenemethanol,.alpha.-bis(trifluoromethyl)-; 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol #; 1,1,1,3,3,3-Hexafluoro-2-phenyl-2-propanol, 99%
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[19] | |||
| Compound Name |
(2E,5E)-5-[(3-Nitrophenyl)methylidene]-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Thiazole analogue, 5; thiazolidinone derivative, 5; CHEMBL272443; BDBM22340; BDBM24518; (5E)-5-[(3-nitrophenyl)methylidene]-2-(1,3-thiazol-2-ylamino)-4,5-dihydro-1,3-thiazol-4-one
Click to Show/Hide
|
||||
| Activity |
Ki = 547500 nM
|
[8] | |||
| Compound Name |
(2E,5E)-5-[(3-Chlorophenyl)methylidene]-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Thiazole analogue, 7; thiazolidinone derivative, 7; CHEMBL405972; BDBM22342; BDBM24520; (5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thiazol-2-ylamino)-4,5-dihydro-1,3-thiazol-4-one
Click to Show/Hide
|
||||
| Activity |
Ki = 1088200 nM
|
[8] | |||
| Compound Name |
2-[(S)-Diethoxyphosphoryl-(4-nitroanilino)methyl]phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946245; BDBM50363854
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
[(S)-(4-Hydroxyanilino)-(2-hydroxyphenyl)methyl]phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946247; BDBM50363856
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
Sodium;(2R)-2-[[[ethoxy(hydroxy)phosphoryl]-(2-hydroxyphenyl)methyl]amino]-3-sulfanylpropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946251
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
2-[(S)-(4-Chloroanilino)-diethoxyphosphorylmethyl]phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946243; BDBM50363852
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
2-[(S)-(4-Bromoanilino)-diethoxyphosphorylmethyl]phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946244; BDBM50363853
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
Sodium;(2S)-2-[[[ethoxy(hydroxy)phosphoryl]-(2-hydroxyphenyl)methyl]amino]-3-(4-hydroxyphenyl)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946383
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
Sodium;(2S,3R)-2-[[[ethoxy(hydroxy)phosphoryl]-(2-hydroxyphenyl)methyl]amino]-3-hydroxybutanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946389
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
Sodium 2-((Ethoxy(Hydroxy)Phosphoryl)(2-Hydroxyphenyl)Methylamino)Acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946387
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
Trimethylenebis[imino[(2-hydroxyphenyl)methylene]]bis(phosphonic acid)dihydrogen diethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946385; BDBM50363864
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
2-[(S)-(2-Chloroanilino)-diethoxyphosphorylmethyl]phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946246; BDBM50363855
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
Sodium;(2S)-2-[[[ethoxy(hydroxy)phosphoryl]-(2-hydroxyphenyl)methyl]amino]-3-(1H-indol-3-yl)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946250
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
Hexamethylenebis[imino[(2-hydroxyphenyl)methylene]]bis(phosphonic acid)dihydrogen diethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946384; BDBM50363863
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
Ethylenebis[imino[(2-hydroxyphenyl)methylene]]bis(phosphonic acid)dihydrogen diethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946386; BDBM50363865
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
Sodium;(2S)-2-[[[ethoxy(hydroxy)phosphoryl]-(2-hydroxyphenyl)methyl]amino]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946388
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Compound Name |
Sodium;(2S)-2-[[[ethoxy(hydroxy)phosphoryl]-(2-hydroxyphenyl)methyl]amino]-3-phenylpropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946252
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[22] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity. Bioorg Med Chem Lett. 2016 Feb 1;26(3):778-781. | ||||
| REF 2 | Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis. ACS Med Chem Lett. 2010 Oct 14;1(7):355-359. | ||||
| REF 3 | Diversity-Oriented Synthesis for Novel, Selective and Drug-like Inhibitors for a Phosphatase from Mycobacterium Tuberculosis. Medchemcomm. 2014 Oct;5(10):1496-1499. | ||||
| REF 4 | A unique and rapid approach toward the efficient development of novel protein tyrosine phosphatase (PTP) inhibitors based on 'clicked' pseudo-glycopeptides. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1092-6. | ||||
| REF 5 | Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2827-32. | ||||
| REF 6 | Synthesis and biological evaluation of novel bis-aromatic amides as novel PTP1B inhibitors. Bioorg Med Chem Lett. 2014 Apr 15;24(8):1889-94. | ||||
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| REF 15 | Brunsvicamides A-C: sponge-related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory activity. J Med Chem. 2006 Aug 10;49(16):4871-8. | ||||
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| REF 17 | Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment. J Med Chem. 2017 Dec 28;60(24):10205-10219. | ||||
| REF 18 | Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold. J Med Chem. 2013 Feb 14;56(3):832-42. | ||||
| REF 19 | Design, synthesis and evaluation of novel 19 F magnetic resonance sensitive protein tyrosine phosphatase inhibitors. Medchemcomm. 2016 Aug 1;7(8):1672-1680. | ||||
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| REF 25 | Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and inhibition of SRC homology 2 domain-containing protein tyrosine phosphatase-2 activity. J Med Chem. 2008 Sep 25;51(18):5650-62. | ||||
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