Target Poor or Non Binder(s) Information
Target General Information | Top | ||||
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Target ID | T14030 | Target Info | |||
Target Name | Ras-related protein Rab-7a (RAB7A) | ||||
Synonyms |
RAB7
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Target Type | Literature-reported Target | ||||
Gene Name | RAB7A | ||||
Biochemical Class | Small GTPase | ||||
UniProt ID |
Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
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Compound Name |
2-[(3-Bromobenzoyl)carbamothioylamino]-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL4099748; KUC109803N; KSC-247-32-1
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Activity |
EC50 ~ 100000 nM
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[1] |
Non Binders of This Target (in total, 3 non binders) | Download | Top | |||
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Compound Name |
5,5-Dimethyl-2-(phenylcarbamothioylamino)-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic acid
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Investigative | Compound Info | ||
Synonyms |
Oprea1_583310; CHEMBL4067445; SCHEMBL15832879; KUC107353N; ZINC4785295; STK075077; AKOS003594414; KSC-13-222; MCULE-3878701448; ST51024328
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Activity |
EC50 > 1000000 nM
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[1] | |||
Compound Name |
2-(Benzylcarbamoylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic acid
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Investigative | Compound Info | ||
Synonyms |
CHEMBL4087195
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Activity |
EC50 > 1000000 nM
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[1] | |||
Compound Name |
Methyl 2-(benzoylcarbamothioylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylate
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Investigative | Compound Info | ||
Synonyms |
CHEMBL4094878; SCHEMBL15832860; KUC107344N; ZINC1060932; KSC-20-023; MCULE-1231328576; SR-01000286347; SR-01000286347-1; Methyl 2-(3-benzoylthioureido)-5,5-dimethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate
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Activity |
EC50 > 1000000 nM
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[1] |
References | Top | ||||
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REF 1 | US patent application no. 8765803B1, Rab7 GTPase inhibitors and related methods of treatment |
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