Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T14181 | Target Info | |||
| Target Name | Telomeric repeat-binding factor 2 (TERF2) | ||||
| Synonyms |
Telomeric DNA-binding protein; TTAGGG repeat-binding factor 2; TRF2; TRBF2
Click to Show/Hide
|
||||
| Target Type | Literature-reported Target | ||||
| Gene Name | TERF2 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 7 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Chembl4170375
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50338582
Click to Show/Hide
|
||||
| Activity |
Ki = 58200 nM
|
[1] | |||
| Compound Name |
Chembl4175252
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50338571
Click to Show/Hide
|
||||
| Activity |
Ki = 61200 nM
|
[1] | |||
| Compound Name |
Chembl4169296
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50338585
Click to Show/Hide
|
||||
| Activity |
Ki = 98000 nM
|
[1] | |||
| Compound Name |
Chembl4165768
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50338569
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[1] | |||
| Compound Name |
Chembl4171529
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50338575
Click to Show/Hide
|
||||
| Activity |
Ki = 115000 nM
|
[1] | |||
| Compound Name |
Chembl4159120
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50338584
Click to Show/Hide
|
||||
| Activity |
Ki = 122600 nM
|
[1] | |||
| Compound Name |
Chembl4172274
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50338562
Click to Show/Hide
|
||||
| Activity |
Ki = 130300 nM
|
[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 2 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Chembl4175096
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50338568
Click to Show/Hide
|
||||
| Activity |
Ki = 461000 nM
|
[1] | |||
| Compound Name |
Chembl4163639
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50338670
Click to Show/Hide
|
||||
| Activity |
Ki > 500000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Cyclic Peptidic Mimetics of Apollo Peptides Targeting Telomeric Repeat Binding Factor 2 (TRF2) and Apollo Interaction. ACS Med Chem Lett. 2018 Apr 25;9(5):507-511. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.