Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T17758 | Target Info | |||
| Target Name | Urokinase-type plasminogen activator (PLAU) | ||||
| Synonyms |
UPA; U-plasminogen activator
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| Target Type | Successful Target | ||||
| Gene Name | PLAU | ||||
| Biochemical Class | Peptidase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 137 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Amiloride
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|
Approved | Compound Info | ||
| Synonyms |
Amiclaran; Amilorida; Amiloridum; Amipramidin; Amipramizid; Amipramizide; Amiprazidine; Amyloride; Guanamprazin; Guanamprazine; Midamor; Amiloride HCL; Amiloride hydrochloride hydrate; Amiclaran (TN); Amikal (Hydrochloride dihydrate); Amilorida [INN-Spanish]; Amiloride (INN); Amiloride [INN:BAN]; Amiloridum [INN-Latin]; Biduret (TN); Midamor (Hydrochloride dihydrate); MK-870 (Hydrochloride dihydrate); AMILORIDE (SEE ALSO: AMILORIDE HCL (2016-88-8)); N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide; N-Amidino-3,5-diamino-6-chlorpyrazincarboxamid; Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride; 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide; 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide; 3,5-diamino-N-[amino(imino)methyl]-6-chloropyrazine-2-carboxamide; 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide; Amiloride (Na-Ca chanel blocker)
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| Activity |
IC50 = 107000 nM
|
[1] | |||
| Compound Name |
PF-429242
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Investigative | Compound Info | ||
| Synonyms |
947303-87-9; PF-429242; (R)-4-((Diethylamino)methyl)-N-(2-methoxyphenethyl)-N-(pyrrolidin-3-yl)benzamide; UNII-49WB3OA7VN; 49WB3OA7VN; PF 429242; PF429242; CHEMBL233611; J-502224; C25H35N3O2; 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide; (R)-4-((Diethylamino)methyl)-N-(2-methoxyphenethyl)-N-(pyrrolidin-3-yl)benz amide; (-)-PF-429242; SCHEMBL2742702; CTK8B5018; DTXSID00635376; EX-A1409; ANW-47048; ZINC28823615; BDBM50216181; AKOS015998619; RL05965; Benzamide, 4-((diethylamino)methyl)-N-(2-(
Click to Show/Hide
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| Activity |
IC50 = 50000 nM
|
[2] | |||
| Compound Name |
(4-bromo-1H-pyrazol-1-yl)(o-tolyl)methanone
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Investigative | Compound Info | ||
| Synonyms |
(4-bromo-1H-pyrazol-1-yl)(2-methylphenyl)methanone; AC1LDSC9; N-Benzoylpyrazole deriv., 23; CHEMBL245163; ZINC37182; BDBM23715; MolPort-002-118-506; STK059624; AKOS001747311; 4-bromopyrazolyl 2-methylphenyl ketone; MCULE-5811997287; ST033218; (4-bromopyrazol-1-yl)-(2-methylphenyl)methanone; SR-01000524307; SR-01000524307-1; 4-bromo-1-[(2-methylphenyl)carbonyl]-1H-pyrazole
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| Activity |
IC50 = 51200 nM
|
[3] | |||
| Compound Name |
1-(3-Nitro-benzyl)-1H-indole-5-carboxamidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL329730; 1-(3-Nitro-benzyl)-1H-indole-5-carboxamidine; BDBM50027293
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| Activity |
Ki ~ 100000 nM
|
[4] | |||
| Compound Name |
1-Benzyl-1H-indole-5-carboxamidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL101343; 1-Benzyl-1H-indole-5-carboxamidine; BDBM50027286
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| Activity |
Ki = 191000 nM
|
[4] | |||
| Compound Name |
1-Phenyl-2-(5-carboxybenzoxazole-2-ylthiomethyl)-5-(pivaloyloxy)-1,4-dihydropyridine-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3093806; BDBM50444295
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
Ethyl 3-[[4-[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-(octylamino)-3-oxopropyl]phenoxy]methyl]benzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752206; BDBM50138890
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-[[3-(pyridin-4-ylmethoxy)phenyl]methoxy]phenyl]propan-2-yl]cyclohexane-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752458; BDBM50138126
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
3-[[12-(Azepan-1-yl)-8-oxo-15-oxa-14-azatetracyclo[7.6.1.02,7.013,16]hexadeca-1(16),2,4,6,9,11,13-heptaen-10-yl]amino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2206359; IPR-803; AC1MV0EA; SCHEMBL12499325; BDBM50401173; MCULE-1693973491; HY-111192; CS-0034598; 3-[3-(Hexahydro-1H-azepine-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazole-5-ylamino]benzoic acid
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| Activity |
IC50 = 50000 nM
|
[7] | |||
| Compound Name |
2-(Benzothiazole-2-ylthiomethyl)-5-(pivaloyloxy)-4H-pyran-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3093815; BDBM50444297
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
2-(5-Carboxybenzoxazole-2-ylthiomethyl)-5-(pivaloyloxy)-4H-pyran-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3093814; BDBM50444296
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
3-Amino-6-chloro-5-(cyanomethylamino)-N-(diaminomethylidene)pyrazine-2-carboxamide;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909791
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| Activity |
IC50 = 50000 nM
|
[8] | |||
| Compound Name |
3-[[4-[(2S)-2-[[4-(Aminomethyl)cyclohexanecarbonyl]amino]-3-(octylamino)-3-oxopropyl]phenoxy]methyl]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3753685; BDBM50138892
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
3,4-Dihydroquinazoline
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Investigative | Compound Info | ||
| Synonyms |
1,4-dihydroquinazoline; CHEMBL539405; Quinazoline, 1,4-dihydro-; 1,4-Dihydro-quinazoline; quinazoline,3,4-dihydro-; 3,4-Dihydroquinazoline #; Benzopyrimidine, 3,4-dihydro-; SCHEMBL1398081; CTK5J5524; ZINC5517570; BDBM50414125; AKOS006352467; EN300-78025
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| Activity |
Ki = 50118.72 nM
|
[9] | |||
| Compound Name |
6-Amino-1-naphthol
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Investigative | Compound Info | ||
| Synonyms |
6-aminonaphthalen-1-ol; 6-Aminonaphthol; 1-Naphthalenol, 6-amino-; 2-Amino-5-naphthol; 1-Naphthalenol,6-amino-; 2-Amino-5-hydroxynaphthalene; CHEMBL551755; EINECS 245-933-6; 6-aminonaphth-1-ol; PubChem12474; 6-Amino-1-naphthol #; 6-Amino-naphthalen-1-ol; ACMC-1CH3W; SCHEMBL588930; QYFYIOWLBSPSDM-UHFFFAOYSA-; 6-Amino-1-naphthol, AldrichCPR; DTXSID60178592; KS-000016DE; ZINC2522861; ANW-25253; BDBM50414134; MFCD00059543; AKOS006228588; VZ30626; AS-57756; SC-72415; DB-046286; A0360; FT-0638368; X5649; J-015262
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| Activity |
Ki = 50118.72 nM
|
[9] | |||
| Compound Name |
1-Aminoisoquinoline
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Investigative | Compound Info | ||
| Synonyms |
Isoquinolin-1-amine; 1-ISOQUINOLINAMINE; isoquinolin-1-ylamine; 1-amino-isoquinoline; UNII-QUG12T52WZ; QUG12T52WZ; isoquinolylamine; CHEMBL62083; MFCD00024137; 1-isoquinolylamine; Isoquinoline, 1-amino-; isoquinolinimine; aminoisoquinoline; EINECS 216-243-2; 1-amino isoquinoline; isoquinolin-1-yl-amine; PubChem18941; 1-Aminoisoquinoline, 99%; SCHEMBL49220; BIDD:GT0381; SCHEMBL4797349; BDBM14320; CTK0H9132; CTK4C1716; DTXSID40165283; ZINC154817; BCP05774; KS-00000N2W; ANW-59241; RW2954; SBB004129; AKOS006220712; CM10316; CS-W000494; MCULE-5885784985; QC-2333; VQ10037; AK-41400; SC-25246; SY007847; TS-01883; AB0008763; DB-043185; fragment 1 (J. med. chem.,50,1116); AM20050832; C3067; FT-0633643; ST50984732; M-3270; AC-907/25014244; J-400099; Q27287501; F8886-6096; Z1741972726
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| Activity |
Ki = 50118.72 nM
|
[9] | |||
| Compound Name |
1-[3-(3-Carbamimidoyl-phenyl)-2-(2,4,6-triisopropyl-benzenesulfonylamino)-propionyl]-piperidine-4-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL323452; BDBM50082189
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| Activity |
Ki = 52000 nM
|
[10] | |||
| Compound Name |
3-[3-(4-Methyl-piperazin-1-yl)-3-oxo-2-(2,4,6-triisopropyl-benzenesulfonylamino)-propyl]-benzamidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL105935; BDBM50082176
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| Activity |
Ki = 52000 nM
|
[10] | |||
| Compound Name |
Guanidine, N-(4-methoxy-2-pyridinyl)-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL55184; BDBM50108367; N-(4-Methoxy-pyridin-2-yl)-guanidine
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| Activity |
Ki = 53300 nM
|
[11] | |||
| Compound Name |
2-[4-[2-[[2-(3-Chlorophenyl)imidazo[1,2-a]pyrazin-3-yl]amino]ethyl]phenyl]guanidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3740795; BDBM50499931
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| Activity |
IC50 = 53780 nM
|
[12] | |||
| Compound Name |
(2-Nitro-phenyl)-guanidine
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Investigative | Compound Info | ||
| Synonyms |
2-(2-nitrophenyl)guanidine; guanidinonitrobenzene; 1-[2-Nitrophenyl]guanidinium; N-(2-Nitro-phenyl)-guanidine; CHEMBL609703; SCHEMBL4905868; SCHEMBL11183085; ZINC25629189; AKOS006317184; J-522964
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| Activity |
Ki = 54300 nM
|
[13] | |||
| Compound Name |
2-Phenyl-1H-benzimidazole-5-carboxamidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL96917; SCHEMBL14599542; BDBM50100891; ZINC12354847; 2-Phenyl-1H-benzoimidazole-5-carboxamidine; 2-Phenyl-3H-benzoimidazole-5-carboxamidine; 2-phenyl-3H-benzimidazole-5-carboximidamide
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| Activity |
Ki = 55000 nM
|
[14] | |||
| Compound Name |
N-[1-(3-Diaminomethyl-benzyl)-2-oxo-2-piperidin-1-yl-ethyl]-4-methyl-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL348266; BDBM50072842; N-[1-(Piperidinocarbonyl)-2-[3-(diaminomethyl)phenyl]ethyl]-4-methylbenzenesulfonamide
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| Activity |
Ki = 55000 nM
|
[15] | |||
| Compound Name |
2-Aminoquinolin-8-ol
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Investigative | Compound Info | ||
| Synonyms |
2-Amino-8-quinolinol; 2-Amino-8-hydroxyquinoline; 8-Quinolinol, 2-amino-; 2-Amino-quinolin-8-ol; CHEMBL119647; 2-azanylquinolin-8-ol; SCHEMBL361523; CTK2H6838; DTXSID00405278; ALBB-021953; ZINC4521140; 0864AC; ANW-53106; BDBM50149208; MFCD00168931; 5-(2-Methylphenyl)-5-oxovalericacid; AKOS015919137; AB04263; CS-W016164; GS-6149; MCULE-2631350821; WT81989; KS-0000268H; AK-45751; BP-13051; SC-47728; 2-Amino-8-quinolinol, >=98.0% (GC); DB-014027; FT-0641268; R2379; ST51036365; 70125-16-5l; 125A165; A836780; Q27451304
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| Activity |
Ki = 56000 nM
|
[16] | |||
| Compound Name |
[1-(3-Carbamimidoyl-benzyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL153334; BDBM50072844
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| Activity |
Ki = 56000 nM
|
[15] | |||
| Compound Name |
3-Amidinophenylalanine deriv., 28
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL211549; BDBM23884
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| Activity |
Ki = 56000 nM
|
[17] | |||
| Compound Name |
2-[4-[[(6-Fluoro-2-pyridin-3-ylimidazo[1,2-a]pyridin-3-yl)amino]methyl]phenyl]guanidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3740195; BDBM50499930
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| Activity |
IC50 = 57550 nM
|
[12] | |||
| Compound Name |
3-[(R)-3-(4-Methanesulfonyl-piperazin-1-yl)-3-oxo-2-(2,2,5,7,8-pentamethyl-chroman-6-sulfonylamino)-propyl]-benzamidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL107743; BDBM50060019
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| Activity |
Ki = 58000 nM
|
[18] | |||
| Compound Name |
Chembl4126725
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Investigative | Compound Info | ||
| Synonyms |
BDBM50272236
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| Activity |
IC50 = 58000 nM
|
[19] | |||
| Compound Name |
3-[3-Morpholin-4-yl-2-(naphthalene-2-sulfonylamino)-3-oxo-propyl]-benzamidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL107210; BDBM50082175
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| Activity |
Ki = 58000 nM
|
[10] | |||
| Compound Name |
N-(4-Guanidino-phenyl)-2-hydroxy-3-methyl-benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL59690; BDBM50115900
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| Activity |
Ki = 60000 nM
|
[20] | |||
| Compound Name |
Chembl4128355
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Investigative | Compound Info | ||
| Synonyms |
BDBM50272180
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| Activity |
IC50 = 60000 nM
|
[19] | |||
| Compound Name |
Diphenyl N-(benzyloxycarbonyl)amino(4-amidinophenyl)methanephosphonate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL238707; SCHEMBL4295336; BDBM50228415; benzyl N-[(4-carbamimidoylphenyl)-diphenoxyphosphorylmethyl]carbamate; 4-Amidino-alpha-(benzyloxycarbonylamino)benzylphosphonic acid diphenyl ester; diphenyl 1-(N-benzyloxycarbonylamino)-1-(4-amidinophenyl)methanephosphonate; [Benzyloxycarbonylamino-(4-carbamimidoyl-phenyl)-methyl]-phosphonic acid diphenyl ester
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| Activity |
IC50 = 60000 nM
|
[21] | |||
| Compound Name |
N-Butyl-3-[[4-(diaminomethylideneamino)phenyl]methylamino]-2-pyridin-3-ylimidazo[1,2-a]pyridine-6-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3741341; BDBM50499903
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| Activity |
IC50 = 60840 nM
|
[12] | |||
| Compound Name |
3-Hydroxy-N-{[4-(N-hydroxycarbamimidoyl)-benzylcarbamoyl]-methyl}-2-phenylmethanesulfonylamino-propionamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL157479; BDBM50110009
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| Activity |
Ki = 61000 nM
|
[22] | |||
| Compound Name |
3-Amino-6-chloro-N-(diaminomethylidene)-5-[2-(2H-tetrazol-5-yl)ethylamino]pyrazine-2-carboxamide;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909794
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| Activity |
IC50 = 61000 nM
|
[8] | |||
| Compound Name |
1-(3-Chlorophenyl)guanidine
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Investigative | Compound Info | ||
| Synonyms |
3-Chlorophenylguanidine; N-(3-chlorophenyl)guanidine; 2-(3-chlorophenyl)guanidine; CHEMBL13823; m-chlorophenylguanidine; SCHEMBL1184744; Guanidine,N-(3-chlorophenyl)-; N-(3-Chloro-phenyl)-guanidine; CTK5B3253; DTXSID20438841; 9218AB; BDBM50053608; MFCD08236718; ZB1102; ZINC13488369; AKOS005208041; 1N-amino(immino)methyl-3-chloroaniline; AB43838; AM81015; MCULE-2184979093; GUANIDINE, N-(3-CHLOROPHENYL)-; DB-072957; FT-0651363; VU0490376-1; L-2332; 145C411; F2158-0392
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| Activity |
Ki = 61659.5 nM
|
[13] | |||
| Compound Name |
2-Naphthalenecarboxamide,6-bromo-N-phenyl-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945239; BDBM50363669
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| Activity |
IC50 ~ 62000 nM
|
[23] | |||
| Compound Name |
3-[4-[(6-Methoxynaphthalen-2-yl)sulfonylamino]phenyl]benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945919; BDBM50363693
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| Activity |
IC50 ~ 62000 nM
|
[23] | |||
| Compound Name |
N-[4-(3-Fluorophenyl)phenyl]-6-methoxynaphthalene-2-sulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945920; BDBM50363694
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| Activity |
IC50 ~ 62000 nM
|
[23] | |||
| Compound Name |
N-[4-(3-Aminophenyl)phenyl]-6-methoxynaphthalene-2-sulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945924; BDBM50363698
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| Activity |
IC50 = 62000 nM
|
[23] | |||
| Compound Name |
6-Methoxy-N-phenylnaphthalene-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945241; BDBM50363671
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| Activity |
IC50 ~ 62000 nM
|
[23] | |||
| Compound Name |
Methyl 6-(phenylcarbamoyl)naphthalene-2-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945242; BDBM50363672
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| Activity |
IC50 ~ 62000 nM
|
[23] | |||
| Compound Name |
2-(3-Methoxy-2-pyridinyl)guanidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL300135; Guanidine, N-(3-methoxy-2-pyridinyl)-; SCHEMBL16571322; 2-(3-methoxypyridin-2-yl)guanidine; BDBM50108359; N-(3-Methoxy-pyridin-2-yl)-guanidine
Click to Show/Hide
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| Activity |
Ki = 62000 nM
|
[11] | |||
| Compound Name |
N-[4-(3-Chlorophenyl)phenyl]-6-methoxynaphthalene-2-sulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945921; BDBM50363695
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| Activity |
IC50 ~ 62000 nM
|
[23] | |||
| Compound Name |
N-Phenylnaphthalene-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945238; N-2-Naphthoyl-anilin; N-phenyl-2-naphthamide; SCHEMBL2467402; CTK2H5384; DTXSID10427547; N-Phenyl-2-naphthalenecarboxamide; ZINC3157812; 2-Naphthalenecarboxamide, N-phenyl-; BDBM50363668; AKOS008463245
Click to Show/Hide
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| Activity |
IC50 ~ 62000 nM
|
[23] | |||
| Compound Name |
6-(Phenylcarbamoyl)naphthalene-2-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945663; SCHEMBL14111908; BDBM50363673
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| Activity |
IC50 ~ 62000 nM
|
[23] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-3-(4-hydroxyphenyl)-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752312; BDBM50138838
Click to Show/Hide
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| Activity |
IC50 = 62000 nM
|
[6] | |||
| Compound Name |
6-Cyano-N-phenylnaphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945237; SCHEMBL7335211; BDBM50363667; ZINC34429683
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62000 nM
|
[23] | |||
| Compound Name |
6-Amino-N-phenylnaphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945240; BDBM50363670
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62000 nM
|
[23] | |||
| Compound Name |
2-[4-[[[2-(4-Ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]methyl]phenyl]guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3739939; BDBM50499918
Click to Show/Hide
|
||||
| Activity |
IC50 = 63920 nM
|
[12] | |||
| Compound Name |
Chembl4126905
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50272238
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[19] | |||
| Compound Name |
Chembl4127304
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50272270
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[19] | |||
| Compound Name |
Benzyl 2-[(6-amino-5-carbamoyl-3-chloropyrazin-2-yl)amino]acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2013184; BDBM50379659
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[24] | |||
| Compound Name |
1-(4-Fluorophenyl)guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
N-(4-FLUORO-PHENYL)-GUANIDINE; 2-(4-fluorophenyl)guanidine; N-(4-FLUOROPHENYL)GUANIDINE; CHEMBL1160766; N-(4-FLUOROPHENYL)-GUANIDINE; Guanidine, (4-fluorophenyl)-; SCHEMBL4029597; CTK1J5800; DTXSID40364299; Guanidine, N-(4-fluorophenyl)-; amino(4-fluorophenyl)carboxamidine; ZINC5342293; 0100AC; ANW-63763; BDBM50261065; MFCD04114639; STK164666; STK508766; AKOS002320984; AKOS005455031; MCULE-6058080593; SB38161; NCGC00340522-01; SC-60366; ST50764253; Z-4772; AB01332579-02; A835226
Click to Show/Hide
|
||||
| Activity |
Ki = 72400 nM
|
[13] | |||
| Compound Name |
3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-pyrrolidin-1-yl-propyl]-benzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL106869; BDBM50082182
Click to Show/Hide
|
||||
| Activity |
Ki = 73000 nM
|
[10] | |||
| Compound Name |
Benzyl 2-[[6-amino-3-chloro-5-[(Z)-N'-hydroxycarbamimidoyl]pyrazin-2-yl]amino]acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2013178; BDBM50379655
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[24] | |||
| Compound Name |
2-Hydroxy-biphenyl-3-carboxylic acid (4-guanidino-phenyl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL291622; BDBM50115890
Click to Show/Hide
|
||||
| Activity |
Ki ~ 75000 nM
|
[20] | |||
| Compound Name |
N-(4-Guanidino-phenyl)-2-hydroxy-5-nitro-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64463; BDBM50115885
Click to Show/Hide
|
||||
| Activity |
Ki ~ 75000 nM
|
[20] | |||
| Compound Name |
Methyl (2R)-1-[(2S)-2-[[3-(3-aminopropanoylamino)phenyl]sulfonylamino]-3-(3-carbamimidoylphenyl)propanoyl]piperidine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492333; BDBM50257761
Click to Show/Hide
|
||||
| Activity |
Ki = 76000 nM
|
[25] | |||
| Compound Name |
Nalpha-[trans-4-(Aminomethyl)cyclohexane-1-Carbonyl]-N-Octyl-O-[(Quinolin-2-Yl)methyl]-L-Tyrosinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752964; PSI-112; BDBM50138893; J3.541.102J
Click to Show/Hide
|
||||
| Activity |
IC50 = 77000 nM
|
[6] | |||
| Compound Name |
2-[[[[(4-Methylphenyl)sulfonyl]amino]acetyl]amino]-3-[3-(diaminomethyl)phenyl]propanoic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL153565; BDBM50072845; 3-(3-Diaminomethyl-phenyl)-2-[2-(toluene-4-sulfonylamino)-acetylamino]-propionic acid methyl ester
Click to Show/Hide
|
||||
| Activity |
Ki = 78000 nM
|
[15] | |||
| Compound Name |
4-Tert-Butoxycarbonylamino-4-{[(4-carbamimidoyl-benzylcarbamoyl)-methyl]-carbamoyl}-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL160580; BDBM50110007
Click to Show/Hide
|
||||
| Activity |
Ki = 82000 nM
|
[22] | |||
| Compound Name |
8-Furan-3-yl-7-methoxy-naphthalene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL104904; BDBM50147087; 8-(furan-3-yl)-7-methoxynaphthalene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 82000 nM
|
[26] | |||
| Compound Name |
2-(4-Methyl-2-pyridinyl)guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL54640; SCHEMBL10310180; BDBM50108366; N-(4-Methyl-pyridin-2-yl)-guanidine
Click to Show/Hide
|
||||
| Activity |
Ki = 83800 nM
|
[11] | |||
| Compound Name |
4-[4-(3-Hydroxyphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL28849; SCHEMBL6925045; BDBM50099902; 4-[4-(3-Hydroxy-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(3-hydroxyphenyl)(1,3-thiazol-2-yl)]-5-methylthiothiophene-2-carboxamidine; 4-[4-(3-hydroxyphenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 86000 nM
|
[27] | |||
| Compound Name |
4-[4-(2-Thienyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL31549; SCHEMBL7738277; BDBM50099933; 5-methylsulfanyl-4-(4-thiophen-2-yl-1,3-thiazol-2-yl)thiophene-2-carboximidamide; 5-Methylsulfanyl-4-(4-thiophen-2-yl-thiazol-2-yl)-thiophene-2-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 89000 nM
|
[27] | |||
| Compound Name |
[4-[3-(Diaminomethylideneamino)propyl]-3,6,9-trioxo-2,5,8-triazabicyclo[8.3.1]tetradeca-1(14),10,12-trien-11-yl]methyl-methyl-phenylsulfanium;bromide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL540392
Click to Show/Hide
|
||||
| Activity |
Ki = 90000 nM
|
[28] | |||
| Compound Name |
(5-Chloro-2-guanidino-pyridin-3-yloxy)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55816; BDBM50108387; [2-(Diaminomethyleneamino)-5-chloro-3-pyridinyloxy]acetic acid
Click to Show/Hide
|
||||
| Activity |
Ki = 90200 nM
|
[29] | |||
| Compound Name |
N-(4-Ethylphenyl)guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-guanidino-4-ethylbenzene; Guanidine, (4-ethylphenyl)-; 2-(4-ethylphenyl)guanidine; 1-(4-ethylphenyl)guanidine; ACMC-20me7z; CHEMBL404605; SCHEMBL3772999; SCHEMBL16562419; CTK0D4043; DTXSID10394482; ZINC4772996; AKOS011664943; MCULE-8487261994; F2158-0690
Click to Show/Hide
|
||||
| Activity |
Ki = 90700 nM
|
[13] | |||
| Compound Name |
4-[4-(1,3-Benzodioxole-5-yl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL31967; SCHEMBL6921158; BDBM50099911; 4-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 91000 nM
|
[27] | |||
| Compound Name |
N-[3-(11-Bromomethyl-3,6,9-trioxo-2,5,8-triaza-bicyclo[8.3.1]tetradeca-1(13),10(14),11-trien-4-yl)-propyl]-guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL38512; BDBM50047473
Click to Show/Hide
|
||||
| Activity |
Ki = 92000 nM
|
[28] | |||
| Compound Name |
(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-Amino-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-11-(carboxymethyl)-23-(hydroxymethyl)-17,26-bis[(4-hydroxyphenyl)methyl]-29-methyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3735080; BDBM50499240
Click to Show/Hide
|
||||
| Activity |
Ki = 93000 nM
|
[30] | |||
| Compound Name |
5-Methylsulfanyl-4-(4-p-tolyl-thiazol-2-yl)-thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29304; SCHEMBL6926657; BDBM50099897; 4-[4-(4-Methylphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine; 4-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 94000 nM
|
[27] | |||
| Compound Name |
4-[4-[4-(Mesylamino)phenyl]-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29332; SCHEMBL6925506; BDBM50099901; 4-[4-(4-Methanesulfonylamino-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-[4-(methanesulfonamido)phenyl]-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 94000 nM
|
[27] | |||
| Compound Name |
4-[4-(4-Chlorophenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL286243; SCHEMBL6924682; BDBM50099900; 4-[4-(4-Chloro-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 99000 nM
|
[27] | |||
| Compound Name |
2-[4-[[[2-(3,5-Dichlorophenyl)imidazo[1,2-a]pyridin-3-yl]amino]methyl]phenyl]guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3741486; BDBM50499928
Click to Show/Hide
|
||||
| Activity |
IC50 = 99160 nM
|
[12] | |||
| Compound Name |
N-(5-Phenyl-isoquinolin-1-yl)-guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL111036; BDBM50147426; ZINC26965583
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[31] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-3-[4-(naphthalen-2-ylmethoxy)phenyl]-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3754274; BDBM50138889
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-3-[4-[(3-aminophenyl)methoxy]phenyl]-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752299; BDBM50138834
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752907; BDBM50138832
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-[[2-(trifluoromethyl)phenyl]methoxy]phenyl]propan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3753322; BDBM50138880
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
(S)-1-(9-Hydroxy-9H-3-aza-fluorene-9-carbonyl)-pyrrolidine-2-carboxylic acid 2-aminomethyl-5-chloro-benzylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL372449; BDBM50164263
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[32] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-(quinolin-8-ylmethoxy)phenyl]propan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752600; BDBM50138888
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-3-[4-(naphthalen-1-ylmethoxy)phenyl]-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3754642; BDBM50138884
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-(4-phenylmethoxyphenyl)propan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3753071; BDBM50138831
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-3-[4-[(3-nitrophenyl)methoxy]phenyl]-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752269; BDBM50138835
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
4-[4-(3,4-Dihydro-2H-1,5-benzodioxepin-7-yl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL281898; BDBM50099915
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[27] | |||
| Compound Name |
1H-Indole-6-carboximidamide, 3-(2,2,2-trifluoroacetyl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL415700; BDBM50027292; 3-(2,2,2-Trifluoro-acetyl)-1H-indole-6-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[4] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]propan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3753340; BDBM50138840
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
Quinoline-2,6-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2,6-Quinolinediamine; uPa_23; CHEMBL538931; SCHEMBL3412309; BDBM92299; DTXSID60621578; MFCD12173224; ZINC35343654; AKOS009511002; MCULE-9046312830; NE52307; AS-41418; SC-68522; EN300-67611; Z1263602381
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[9] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-[(3-phenylphenyl)methoxy]phenyl]propan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752061; BDBM50138894
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
4-[[4-[(2S)-2-[[4-(Aminomethyl)cyclohexanecarbonyl]amino]-3-(octylamino)-3-oxopropyl]phenoxy]methyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752906; BDBM50138885
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
4-(Aminomethyl)-N-[(2S)-1-(octylamino)-1-oxo-3-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]propan-2-yl]cyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752559; BDBM50138882
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
1H-Indole-6-carboximidamide, 3-acetyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL321524; 3-Acetyl-1H-indole-6-carboxamidine; BDBM50027283
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[4] | |||
| Compound Name |
2-[4-[[[2-(3-Fluorophenyl)imidazo[1,2-a]pyridin-3-yl]amino]methyl]phenyl]guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3740693; BDBM50499932
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[12] | |||
| Compound Name |
3-[[6-Amino-3-chloro-5-(diaminomethylidenecarbamoyl)pyrazin-2-yl]amino]propanoic acid;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909783
Click to Show/Hide
|
||||
| Activity |
IC50 = 102000 nM
|
[8] | |||
| Compound Name |
N-(2-Chloro-phenyl)-guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
N-(2-chlorophenyl)guanidine; 1-(2-chlorophenyl)guanidine; 2-(2-chlorophenyl)guanidine; CHEMBL41853; N-(2-chlorophenyl)-guanidine; SCHEMBL1187007; CTK4F2856; DTXSID80482582; Guanidine, N-(2-chlorophenyl)-; 4355AJ; BDBM50053633; ZINC26743893; AKOS011667952; 1N-amino(immino)methyl-2-chloroaniline; NE63422; SB36019; SC-60368; FT-0693149; A817068; J-015339; J-522897
Click to Show/Hide
|
||||
| Activity |
Ki = 103000 nM
|
[13] | |||
| Compound Name |
4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL285325; SCHEMBL6927336; BDBM50099896; 4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 108000 nM
|
[27] | |||
| Compound Name |
UCD74A HCl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909781; N-[6-Amino-5-[[(aminoiminomethyl)amino]carbonyl]-3-chloro-2-pyrazinyl]-glycine hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[8] | |||
| Compound Name |
3-[(R)-3-(4-Methyl-piperazin-1-yl)-2-(naphthalene-2-sulfonylamino)-3-oxo-propyl]-benzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL107911; BDBM50060031
Click to Show/Hide
|
||||
| Activity |
Ki = 110000 nM
|
[18] | |||
| Compound Name |
4-[4-(3-Methoxyphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29205; SCHEMBL6927408; BDBM50099903; 4-[4-(3-Methoxy-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 115000 nM
|
[27] | |||
| Compound Name |
4-[4-(2-Chloro-4-pyridinyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29048; SCHEMBL6927284; BDBM50099913; 4-[4-(2-Chloro-pyridin-4-yl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(2-chloropyridin-4-yl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 120000 nM
|
[27] | |||
| Compound Name |
3-Amino-N-(diaminomethylidene)-5-(2-phenylethylamino)pyrazine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909644
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[8] | |||
| Compound Name |
Chembl2332610
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2448530; BDBM50431220
Click to Show/Hide
|
||||
| Activity |
Ki ~ 120000 nM
|
[33] | |||
| Compound Name |
Chembl2332604
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2448529; BDBM50431213
Click to Show/Hide
|
||||
| Activity |
Ki ~ 120000 nM
|
[33] | |||
| Compound Name |
2-[4-[[[2-(4-Fluorophenyl)imidazo[1,2-a]pyridin-3-yl]amino]methyl]phenyl]guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3739666; BDBM50499907
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[12] | |||
| Compound Name |
Methyl (2S)-1-[(2S)-2-[[3-(3-aminopropanoylamino)phenyl]sulfonylamino]-3-(3-carbamimidoylphenyl)propanoyl]piperidine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492334; BDBM50257762
Click to Show/Hide
|
||||
| Activity |
Ki = 126000 nM
|
[25] | |||
| Compound Name |
US8569313, Inhibitor 35
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466585; SCHEMBL8201046; SCHEMBL19309576; BDBM104920; BDBM50254024
Click to Show/Hide
|
||||
| Activity |
Ki = 129000 nM
|
[34] | |||
| Compound Name |
4-[4-(2-Methoxyphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL283080; SCHEMBL6927300; BDBM50099898; 4-[4-(2-Methoxy-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(2-methoxyphenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 130000 nM
|
[27] | |||
| Compound Name |
1H-Indole-5-carboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1H-Indole-5-carboxamidine; 5-Amidinoindole; CHEMBL26490; SCHEMBL563181; CTK2I0095; ZINC1439372; 4714AH; BDBM50027306; AKOS006352033; AB18264; SC-58549; DB-074491; FT-0756503
Click to Show/Hide
|
||||
| Activity |
Ki = 131000 nM
|
[4] | |||
| Compound Name |
N-(2-Methoxy-phenyl)-guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-(2-methoxyphenyl)guanidine; 2-(2-methoxyphenyl)guanidine; N-(2-methoxyphenyl)guanidine; (2-methoxy-phenyl)-guanidine; SCHEMBL1185416; CHEMBL1160764; CTK5B3609; N''-(2-Methoxyphenyl)guanidine; DTXSID60491430; ZINC2526902; 4356AJ; AKOS005208357; MCULE-5448883110; SB37949; SC-60369; FT-0690620; L-2333; A833387; J-522954; F2158-0399
Click to Show/Hide
|
||||
| Activity |
Ki = 136000 nM
|
[13] | |||
| Compound Name |
4-[4-(2-Naphthyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29290; SCHEMBL6924361; BDBM50099936; 5-methylsulfanyl-4-(4-naphthalen-2-yl-1,3-thiazol-2-yl)thiophene-2-carboximidamide; 5-Methylsulfanyl-4-(4-naphthalen-2-yl-thiazol-2-yl)-thiophene-2-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 138000 nM
|
[27] | |||
| Compound Name |
3-[(R)-3-[4-(2-Hydroxy-ethyl)-piperazin-1-yl]-2-(naphthalene-2-sulfonylamino)-3-oxo-propyl]-benzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL107282; BDBM50060024
Click to Show/Hide
|
||||
| Activity |
Ki = 140000 nM
|
[18] | |||
| Compound Name |
Chembl4129836
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50272185
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[19] | |||
| Compound Name |
4-(4-Benzo[b]thiophen-3-yl-thiazol-2-yl)-5-methylsulfanyl-thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL28875; BDBM50099935
Click to Show/Hide
|
||||
| Activity |
Ki = 141000 nM
|
[27] | |||
| Compound Name |
4-[4-(5,6,7,8-Tetrahydronaphthalene-2-yl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL280975; SCHEMBL7736599; BDBM50099919; 5-Methylsulfanyl-4-[4-(5,6,7,8-tetrahydro-naphthalen-2-yl)-thiazol-2-yl]-thiophene-2-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 145000 nM
|
[27] | |||
| Compound Name |
2-(3-Hydroxy-2-pyridinyl)guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55051; Guanidine, N-(3-hydroxy-2-pyridinyl)-; BDBM50108356; N-(3-Hydroxy-pyridin-2-yl)-guanidine
Click to Show/Hide
|
||||
| Activity |
Ki = 147000 nM
|
[11] | |||
| Compound Name |
2-[4-[2-[(2-Ethylimidazo[1,2-a]pyridin-3-yl)amino]ethyl]phenyl]guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3740173; BDBM50499935
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[12] | |||
| Compound Name |
(R)-N-[(5-Chloro-2-ethyl-benzylcarbamoyl)-methyl]-4-(1-oxy-pyridin-2-yl)-2-phenylmethanesulfonylamino-butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL397921; SCHEMBL8242474; BDBM50211564
Click to Show/Hide
|
||||
| Activity |
Ki = 150000 nM
|
[35] | |||
| Compound Name |
(S)-Ethyl 1-(5-(4-phenethoxybenzyl)-1,2,4-oxadiazol-3-yl)-6-amino-1-oxohexan-2-ylcarbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL211561; BDBM50187800
Click to Show/Hide
|
||||
| Activity |
Ki ~ 150000 nM
|
[36] | |||
| Compound Name |
N-[(2S)-6-Amino-1-[5-[[4-[2-(3,4-dichlorophenyl)ethoxy]phenyl]methyl]-1,2,4-oxadiazol-3-yl]-1-oxohexan-2-yl]-3,4-difluorobenzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL536972
Click to Show/Hide
|
||||
| Activity |
Ki ~ 150000 nM
|
[37] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-3-methylbutyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3800401; BDBM50500937
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[38] | |||
| Compound Name |
4-[4-(2,4-Dimethoxyphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL286267; SCHEMBL6927513; BDBM50099914; 4-[4-(2,4-Dimethoxy-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(2,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 152000 nM
|
[27] | |||
| Compound Name |
4-[4-(2-Chloro-3-pyridinyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL285818; SCHEMBL6923479; BDBM50099920; 4-[4-(2-Chloro-pyridin-3-yl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(2-chloropyridin-3-yl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 154000 nM
|
[27] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3800020; BDBM50500941
Click to Show/Hide
|
||||
| Activity |
IC50 = 160000 nM
|
[38] | |||
| Compound Name |
4-[4-(3-Nitro-4-chlorophenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL413764; SCHEMBL6922189; BDBM50099918; 4-[4-(4-Chloro-3-nitro-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(4-chloro-3-nitrophenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 161000 nM
|
[27] | |||
| Compound Name |
4-[4-(4-Chloro-3-pyridinyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL28723; SCHEMBL7738273; BDBM50099917; 4-[4-(4-Chloro-pyridin-3-yl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(4-chloropyridin-3-yl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 164000 nM
|
[27] | |||
| Compound Name |
2-(3-Phenyl-5-chloro-2-pyridinyl)guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL56959; BDBM50108377; N-(5-Chloro-3-phenyl-pyridin-2-yl)-guanidine
Click to Show/Hide
|
||||
| Activity |
Ki = 166300 nM
|
[29] | |||
| Compound Name |
2-(6-Methyl-2-pyridinyl)guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL54545; 2-(6-methylpyridin-2-yl)guanidine; BDBM50108357; N-(6-Methyl-pyridin-2-yl)-guanidine; Guanidine, N-(6-methyl-2-pyridinyl)-
Click to Show/Hide
|
||||
| Activity |
Ki = 173000 nM
|
[11] | |||
| Compound Name |
3-Amino-6-chloro-N-(diaminomethylidene)-5-(2H-tetrazol-5-ylmethylamino)pyrazine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909792
Click to Show/Hide
|
||||
| Activity |
IC50 = 177000 nM
|
[8] | |||
| Compound Name |
4-[4-(Phenoxymethyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL287292; SCHEMBL6925432; BDBM50099937; 5-Methylsulfanyl-4-(4-phenoxymethyl-thiazol-2-yl)-thiophene-2-carboxamidine; 5-methylsulfanyl-4-[4-(phenoxymethyl)-1,3-thiazol-2-yl]thiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 178000 nM
|
[27] | |||
| Compound Name |
(2S)-1-[(2S)-2-[[3-(3-Aminopropanoylamino)phenyl]sulfonylamino]-3-(3-carbamimidoylphenyl)propanoyl]piperidine-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495010; BDBM50257811
Click to Show/Hide
|
||||
| Activity |
Ki = 193000 nM
|
[25] | |||
| Compound Name |
1-Methyl-1h-indole-5-carboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL101878; SCHEMBL1817590; 1-Methyl-1H-indole-5-carboxamidine; BDBM50027300; 1-METHYLINDOLE-5-CARBOXIMIDAMIDE
Click to Show/Hide
|
||||
| Activity |
Ki = 196000 nM
|
[4] | |||
| Compound Name |
2-Aminobenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1H-Benzimidazol-2-amine; 1H-Benzo[d]imidazol-2-amine; 2-Iminobenzimidazoline; Benzimidazol-2-ylamine; Benzimidazole, 2-amino-; 2-Amino benzimidazole; 2-Amino-1H-benzimidazole; 1H-1,3-benzodiazol-2-amine; USAF EK-4037; 2-Benzimidazolamine; aminobenzimidazole; MFCD00005596; UNII-E65DE7521V; 1H-benzimidazol-2-ylamine; 1H-Benzoimidazol-2-ylamine; CHEMBL305513; E65DE7521V; benzimidazole-2-ylamine; DSSTox_CID_4465; DSSTox_RID_77410; DSSTox_GSID_24465; 2-Aminobenzimidazole, 99+%; WLN: T56 BM DNJ CZ; Caswell No. 033AA; CCRIS 4354; NSC 7628; EINECS 213-280-6; NSC 27793; BRN 0116525; AI3-60094; benzimidazole amine; benzimidazole-amine; 2-ammobenzimidazole; CRA Fragment 9; 2-amino-benzimidazol; benzimidazol-2-amine; 2-aminobenzoimidazole; zlchem 194; 2-amino-benzimidazole; PubChem9020; ACMC-209rlr; 1H-benzoimidazol-2-amine; Imidazole C-2 deriv. 3; SCHEMBL9098; 2-Aminobenzimidazole, 97%; Oprea1_243328; 5-25-10-00372 (Beilstein Handbook Reference); JMC524454 Compound 5; KSC488C2F; MLS001074865; 1H-benz[d]imidazole-2-amine; BIDD:GT0837; 1H-1,3-benzimidazol-2-amine; BDBM7960; SCHEMBL2475507; SCHEMBL3350089; DTXSID1024465; CTK3I8122; EBD2768; NSC7628; ZLB0185; HMS1741L08; HMS2865C12; ACT05692; CS-D1373; NSC-7628; NSC27793; STR00452; Tox21_201949; Tox21_303120; ANW-40045; BBL033933; NSC-27793; SBB028244; STL283126; ZINC16889973; AKOS000104081; LS11771; MCULE-2427064128; KS-000000W6; NCGC00091178-01; NCGC00091178-02; NCGC00257027-01; NCGC00259498-01; AC-15858; AK-54965; AM804572; SC-07373; SMR000019082; SY032901; TS-01718; 1,3-dihydro-benzoimidazol-2-ylidene amine; A0850; EU-0067838; FT-0611230; ST50949412; C10901; M-6487; 49803-EP2295432A1; 49803-EP2298738A1; 49803-EP2311825A1; AQ-738/40188880; Q-101103; Q27103356; F0266-1828; Z104378302
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[39] | |||
| Compound Name |
2-[4-[[[2-Pyridin-3-yl-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]amino]methyl]phenyl]guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3739955; BDBM50499904
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[12] | |||
| Compound Name |
2-[4-(Imidazo[1,2-a]pyridin-3-ylamino)butyl]guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3740528; BDBM50499924
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[12] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 118 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
4-(5-Nitro-indol-1-ylmethyl)-benzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL100296; 4-(5-Nitro-indol-1-ylmethyl)-benzamidine
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[4] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1S)-1-[3-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3799135; BDBM50500945
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[38] | |||
| Compound Name |
2-Chloro-benzenesulfonic acid 3-(3-guanidino-propoxy)-5-methyl-phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL291062; BDBM50070598
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[40] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238362; BDBM50009171
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[41] | |||
| Compound Name |
2-Chlorobenzenesulfonic acid 3-methyl-5-(1-amidinopiperidine-4-ylmethoxy)phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41876; SCHEMBL7446067; BDBM50070597; 2-Chloro-benzenesulfonic acid 3-(1-carbamimidoyl-piperidin-4-ylmethoxy)-5-methyl-phenyl ester
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[40] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1S)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-2-methylpropyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3797774; BDBM50500940
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[38] | |||
| Compound Name |
Ethyl 4-[[4-[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-(octylamino)-3-oxopropyl]phenoxy]methyl]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3754802; BDBM50138891
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[6] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1S)-1-[2,5-dioxo-3-(4-pyridin-4-yloxyphenyl)imidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3800112; BDBM50500944
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[38] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-pyridin-4-yloxyphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3585745; BDBM50093541
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[41] | |||
| Compound Name |
2-Chloro-benzenesulfonic acid 3-(1-carbamimidoyl-piperidin-3-ylmethoxy)-5-methyl-phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41862; SCHEMBL7440084; BDBM50070600
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[40] | |||
| Compound Name |
Methyl 2-[[4-[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-(octylamino)-3-oxopropyl]phenoxy]methyl]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3753392; BDBM50138881
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[6] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-7-methyl-6-[[5-oxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]methyl]pyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233152; BDBM50009209
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[42] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R)-1-[2,5-dioxo-3-(4-pyridin-4-yloxyphenyl)imidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3799182; BDBM50500942
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[38] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[[2,5-dioxo-3-(4-pyridin-4-yloxyphenyl)imidazolidin-1-yl]methyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3585746; BDBM50093540
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[41] | |||
| Compound Name |
2-Chlorobenzenesulfonic acid 3-methyl-5-(4-guanidinobutoxy)phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL287807; BDBM50070599; 2-Chloro-benzenesulfonic acid 3-(4-guanidino-butoxy)-5-methyl-phenyl ester
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[40] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R,2R)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-2-methylbutyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3798282; BDBM50500939
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[38] | |||
| Compound Name |
2-Chlorophenyl[3-[2-[methyl(4-pyridyl)amino]ethoxy]-5-methylphenoxy] sulfone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289951; SCHEMBL8545290; BDBM50064653; [3-methyl-5-[2-[methyl(pyridin-4-yl)amino]ethoxy]phenyl] 2-chlorobenzenesulfonate; 2-Chloro-benzenesulfonic acid 3-methyl-5-[2-(methyl-pyridin-4-yl-amino)-ethoxy]-phenyl ester
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[40] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[[3-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3585742; BDBM50093542
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[38] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238374; BDBM50009200
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[41] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1S)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3799525; BDBM50500943
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[38] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-2-methylpropyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3799985; BDBM50500938; J3.591.431E
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[38] | |||
| Compound Name |
2-Chloro-benzenesulfonic acid 3-(5-guanidino-pentyloxy)-5-methyl-phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL287910; BDBM50070595
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[40] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R)-1-[3-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3799329; BDBM50500946
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[38] | |||
| Compound Name |
N-Quinolin-2-yl-guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL109751; guanidinoquinoline; 2-quinolin-2-ylguanidine; Guanidine, N-2-quinolinyl-; SCHEMBL6191463; BDBM50147421
Click to Show/Hide
|
||||
| Activity |
Ki = 209000 nM
|
[31] | |||
| Compound Name |
2-[(6-Amino-5-carbamimidoylpyrazin-2-yl)amino]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2013183; BDBM50379658
Click to Show/Hide
|
||||
| Activity |
IC50 = 212000 nM
|
[24] | |||
| Compound Name |
4-Amino-5-chloro-N-(diaminomethylidene)-2-methoxybenzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911976
Click to Show/Hide
|
||||
| Activity |
IC50 > 222000 nM
|
[8] | |||
| Compound Name |
2-[[6-Amino-3-chloro-5-[(Z)-N'-hydroxycarbamimidoyl]pyrazin-2-yl]amino]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2013179; BDBM50379663
Click to Show/Hide
|
||||
| Activity |
IC50 = 231000 nM
|
[24] | |||
| Compound Name |
2-[(6-Amino-5-carbamimidoyl-3-chloropyrazin-2-yl)amino]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2013182; SCHEMBL10087502; BDBM50379657
Click to Show/Hide
|
||||
| Activity |
IC50 = 237000 nM
|
[24] | |||
| Compound Name |
3-[4-[(6-Cyanonaphthalene-2-carbonyl)amino]phenyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945763; BDBM50363682
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[23] | |||
| Compound Name |
2-[4-[[(2-Piperidin-4-ylimidazo[1,2-a]pyridin-3-yl)amino]methyl]phenyl]guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3741372; BDBM50499901
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[12] | |||
| Compound Name |
[1-[(Benzyloxycarbonyl)amino]-4-aminobutyl]phosphonic acid diphenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL9971041; CHEMBL1179439
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[43] | |||
| Compound Name |
2-[4-[[(2-Pyridin-3-ylimidazo[1,2-a]pyridin-3-yl)amino]methyl]phenyl]guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3741137; BDBM50499923
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[12] | |||
| Compound Name |
N-[2-(2,4-Dichlorophenoxy)ethyl]imidazo[1,2-a]pyridin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3740414; BDBM50499934
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[12] | |||
| Compound Name |
N-o-Tolyl-guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-(o-tolyl)guanidine; 2-(2-methylphenyl)guanidine; tolylguanidine; 1-(2-methylphenyl)guanidine; 1-o-tolylguanidine; 2-(tolyl)guanidine; SCHEMBL467514; CHEMBL1160769; CTK8G2019; DTXSID10328323; Guanidine, N-(2-methylphenyl)-; ZINC6523257; 7575AH; MFCD04114636; AKOS005207281; AKOS030241285; MCULE-9370377038; SB36908; BB 0254994; FT-0690624; FT-0695859; A-7169; F2158-0398
Click to Show/Hide
|
||||
| Activity |
Ki = 258821.29 nM
|
[13] | |||
| Compound Name |
3-Benzoyl-1H-indole-6-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL102009; BDBM50027289; ZINC26745044
Click to Show/Hide
|
||||
| Activity |
Ki = 267000 nM
|
[4] | |||
| Compound Name |
4-[4-(4-Nitrophenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29006; SCHEMBL6920303; BDBM50099929; 5-Methylsulfanyl-4-[4-(4-nitro-phenyl)-thiazol-2-yl]-thiophene-2-carboxamidine; 5-methylsulfanyl-4-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]thiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 270000 nM
|
[27] | |||
| Compound Name |
5-Methylsulfanyl-4-[4-(4-p-tolylsulfamoyl-phenyl)-thiazol-2-yl]-thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29208; BDBM50099905
Click to Show/Hide
|
||||
| Activity |
Ki = 272000 nM
|
[27] | |||
| Compound Name |
5-Methylsulfanyl-4-(4-o-tolyl-thiazol-2-yl)-thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL28949; SCHEMBL6927431; BDBM50099907; 4-[4-(2-Methylphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine; 4-[4-(2-methylphenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 277000 nM
|
[27] | |||
| Compound Name |
2-[[6-Amino-5-[(Z)-N'-hydroxycarbamimidoyl]pyrazin-2-yl]amino]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2013180; BDBM50379654
Click to Show/Hide
|
||||
| Activity |
IC50 = 279000 nM
|
[24] | |||
| Compound Name |
1H-Indole-5-carboximidamide, 1-ethyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL322894; 1-Ethyl-1H-indole-5-carboxamidine; BDBM50027294
Click to Show/Hide
|
||||
| Activity |
Ki = 280000 nM
|
[4] | |||
| Compound Name |
Chembl4128554
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50272187
Click to Show/Hide
|
||||
| Activity |
IC50 = 280000 nM
|
[19] | |||
| Compound Name |
4-[4-(2,4-Dichlorophenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL285142; SCHEMBL6924035; BDBM50099916; 4-[4-(2,4-Dichloro-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 287000 nM
|
[27] | |||
| Compound Name |
1-(Pyrimidin-2-yl)guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL54989; 2-pyrimidin-2-ylguanidine; guanidinopyrimidine; pyrimidin-2-yl-guanidine; N-pyrimidin-2-ylguanidine; N-Pyrimidin-2-yl-guanidine; 2-(2-Pyrimidinyl)guanidine; SCHEMBL2780925; SCHEMBL19059123; DTXSID10482590; (PYRIMIDIN-2-YL)GUANIDINE; BDBM50108368; ZINC13436468; AKOS006327502; AB52859
Click to Show/Hide
|
||||
| Activity |
Ki = 292000 nM
|
[11] | |||
| Compound Name |
4-(4-Phenyl-5-methyl-2-thiazolyl)-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29268; SCHEMBL6923828; BDBM50099927; 4-(5-methyl-4-phenyl-1,3-thiazol-2-yl)-5-methylsulfanylthiophene-2-carboximidamide; 4-(5-Methyl-4-phenyl-thiazol-2-yl)-5-methylsulfanyl-thiophene-2-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 305000 nM
|
[27] | |||
| Compound Name |
4-[4-(4-Methoxyphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL28618; SCHEMBL6921141; BDBM50099904; 4-[4-(4-Methoxy-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 327000 nM
|
[27] | |||
| Compound Name |
Guanidine, (aminophenyl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ACMC-20mioi; 2-(2-aminophenyl)guanidine; N-(2-Aminophenyl)-guanidine; N''-(2-Aminophenyl)guanidine; SCHEMBL1999856; CHEMBL1160768; CTK0C9065; DTXSID80613814; AKOS006318455; J-522867
Click to Show/Hide
|
||||
| Activity |
Ki = 388000 nM
|
[13] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-sulfamoylphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238365; BDBM50009174
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[42] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[4-(4-methoxyphenoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238375; BDBM50009201
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[42] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-quinolin-6-yloxyphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238377; BDBM50009203
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[42] | |||
| Compound Name |
N-[3-(Trifluoromethyl)phenyl]guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[3-(trifluoromethyl)phenyl]guanidine; 1-[3-(trifluoromethyl)phenyl]guanidine; CHEMBL44236; N-(3-Trifluoromethyl-phenyl)-guanidine; 1-(3-(trifluoromethyl)phenyl)guanidine; PubChem22165; SCHEMBL1999954; CTK9A2130; DTXSID60409156; ZINC1565193; N-(3-trifluoromethylphenyl)guanidine; BDBM50053603; AKOS005208021; MCULE-4422961857; SC-26169; N-(3-TRIFLUOROMETHYL-PHENYL)-GUANIDIN; 1N-amino(immino)methyl-3-trifluoromethylaniline; L-2339; F2158-0385
Click to Show/Hide
|
||||
| Activity |
Ki = 418793.57 nM
|
[13] | |||
| Compound Name |
4-[4-(3-Bromophenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL285593; SCHEMBL6926174; BDBM50099930; 4-[4-(3-Bromo-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine; 4-[4-(3-bromophenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 442000 nM
|
[27] | |||
| Compound Name |
4-(4-Benzyl-2-thiazolyl)-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29269; SCHEMBL6928434; BDBM50099909; 4-(4-benzyl-1,3-thiazol-2-yl)-5-methylsulfanylthiophene-2-carboximidamide; 4-(4-Benzyl-thiazol-2-yl)-5-methylsulfanyl-thiophene-2-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 470000 nM
|
[27] | |||
| Compound Name |
(2S)-1-[(2R)-2-Amino-3,3-diphenylpropanoyl]-N-[1-(diaminomethylideneamino)-5,8-dioxo-8-piperidin-1-yloctan-4-yl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1202120
Click to Show/Hide
|
||||
| Activity |
Ki = 494000 nM
|
[44] | |||
| Compound Name |
N-[4-(Aminomethyl)cyclohexyl]imidazo[1,2-a]pyridin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3740839; BDBM50499927
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[12] | |||
| Compound Name |
Imidazo[1,2-a]pyridin-3-amine,n-[4-(aminomethyl)phenyl]-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3741382; BDBM50499909; ZINC89201128
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[12] | |||
| Compound Name |
[4-(4-Aminobutyl)-3,6,9-trioxo-2,5,8-triazabicyclo[8.3.1]tetradeca-1(14),10,12-trien-11-yl]methyl-methyl-phenylsulfanium;bromide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL557221
Click to Show/Hide
|
||||
| Activity |
Ki = 500000 nM
|
[28] | |||
| Compound Name |
N-[4-(2-Aminoethoxy)-3,5-dichlorophenyl]imidazo[1,2-a]pyridin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3740983; BDBM50499902
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[12] | |||
| Compound Name |
5-Methylsulfanyl-4-(4-m-tolyl-thiazol-2-yl)-thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL286498; SCHEMBL6921838; BDBM50099924; 4-[4-(3-Methylphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine; 4-[4-(3-methylphenyl)-1,3-thiazol-2-yl]-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 546000 nM
|
[27] | |||
| Compound Name |
Cyanopeptolin 1020
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1172449
Click to Show/Hide
|
||||
| Activity |
IC50 > 605000 nM
|
[45] | |||
| Compound Name |
4-(4-Cyclohexyl-2-thiazolyl)-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL283859; SCHEMBL6924795; BDBM50099925; 4-(4-Cyclohexyl-thiazol-2-yl)-5-methylsulfanyl-thiophene-2-carboxamidine; 4-(4-cyclohexyl-1,3-thiazol-2-yl)-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 641000 nM
|
[27] | |||
| Compound Name |
1-(4-Methoxyphenyl)guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
N-(4-METHOXY-PHENYL)-GUANIDINE; 2-(4-methoxyphenyl)guanidine; N-(4-methoxyphenyl)guanidine; CHEMBL297076; PubChem22162; Guanidine, (4-methoxyphenyl)-; SCHEMBL1186050; CTK1J3462; DTXSID50394385; ALBB-019787; ZINC4772989; 0374AC; ANW-73765; BDBM50100969; MFCD04114642; AKOS000266462; MCULE-7391942405; NE63170; SB38240; 1N-amino(immino)methyl-4-methoxyaniline; SC-26149; FT-0691243; A835754; guanidine, N-(4-methoxyphenyl)-, nitrate (1:1)
Click to Show/Hide
|
||||
| Activity |
Ki = 676000 nM
|
[13] | |||
| Compound Name |
4-Guanidinobenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
p-Guanidinobenzoic acid; 4-carbamimidamidobenzoic acid; 4-Guanidinobenzoate; 4-Guanidino-benzoic acid; 4-(diaminomethylideneamino)benzoic acid; 4-amino(immino)methylaminobenzoate; 4-Guanidinobenzoicacidhydrochloride; 4-[(???methyl)amino]benzoic acid; para-Guanidinobenzoate; 4-guanidino benzoic acid; CHEMBL20767; SCHEMBL211005; DTXSID90936349; BDBM237208; ZINC155851; BBL034734; BDBM50014341; MFCD00152515; SBB005807; STL426033; AKOS006228263; DB02459; MCULE-1232888650; 4-((Aminoiminomethyl)amino)benzoic acid; FT-0686410; ST50825135; 060G654; Q27093453
Click to Show/Hide
|
||||
| Activity |
Ki = 744731.97 nM
|
[13] | |||
| Compound Name |
3-[2-Amino-3-(4-methyl-piperidin-1-yl)-3-oxo-propyl]-benzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL358387; BDBM50072849
Click to Show/Hide
|
||||
| Activity |
Ki = 800000 nM
|
[15] | |||
| Compound Name |
4-(4-Methyl-2-thiazolyl)-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL285330; SCHEMBL6921044; BDBM50099908; 5-methylsulfanyl-4-(4-methyl-1,3-thiazol-2-yl)thiophene-2-carboximidamide; 5-Methylsulfanyl-4-(4-methyl-thiazol-2-yl)-thiophene-2-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 815000 nM
|
[27] | |||
| Compound Name |
4-(4,5-Diphenyl-2-thiazolyl)-5-(methylthio)thiophene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL27566; SCHEMBL6924362; BDBM50099931; 4-(4,5-Diphenyl-thiazol-2-yl)-5-methylsulfanyl-thiophene-2-carboxamidine; 4-(4,5-diphenyl-1,3-thiazol-2-yl)-5-methylsulfanylthiophene-2-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 982000 nM
|
[27] | |||
| Compound Name |
3-(4-Amidinophenyl)-2-[[[(4-amidinophenylsulfonyl)amino]acetyl]amino]propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL341933; BDBM50067526; 2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetylamino]-3-(4-carbamimidoyl-phenyl)-propionic acid
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[46] | |||
| Compound Name |
3-(3-Amidinophenyl)-2-[[[(4-thiocarbamoylphenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL336844; BDBM50067528
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[46] | |||
| Compound Name |
Mupain-1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3734777; BDBM50499239
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[30] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[4-(cyanomethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238373; BDBM50009199
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-[4-(2-oxopropoxy)phenyl]imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238371; BDBM50009188
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
3-Amino-N-{3-[(S)-2-[4-(2-amino-ethyl)-piperidin-1-yl]-1-(4-aminomethyl-benzyl)-2-oxo-ethylsulfamoyl]-phenyl}-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL462253; BDBM50253981
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[34] | |||
| Compound Name |
3,5-Diamino-6-chloropyrazine-2-carbohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911978; SCHEMBL14932731; CTK2F1286; DTXSID40488247; ZINC2511147; BDBM50356117; DA-24662; FT-0711426; N-amino-3,5-diamino-6-chloropyrazine-2-carboxamide; Pyrazinecarboxylic acid, 3,5-diamino-6-chloro-, hydrazide
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-fluorophenyl)-5-oxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233151; BDBM50009208
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-cyanophenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238367; BDBM50009176
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
2-[[6-Amino-3-chloro-5-(diaminomethylidenecarbamoyl)pyrazin-2-yl]amino]ethylphosphonic acid;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909788
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
3-Amino-N-{3-[(S)-2-[4-(2-amino-ethyl)-piperidin-1-yl]-1-(3-aminomethyl-benzyl)-2-oxo-ethylsulfamoyl]-phenyl}-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459525; SCHEMBL8197411; BDBM50253954; US8569313, 61
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[34] | |||
| Compound Name |
3-(3-Amino-1,2,4-oxadiazol-5-yl)-5-chloro-2,6-pyrazinediamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Cgs-4270; 3-(3-amino-1,2,4-oxadiazol-5-yl)-5-chloropyrazine-2,6-diamine; CHEMBL290169; SCHEMBL11053565; CTK5D8392; DTXSID90223847; 3-Amino-5-(3,5-diamino-6-chloropyrazin-2-yl)-1,2,4-oxadiazole; ZINC3647621; BDBM50356116; DA-25292; FT-0743072; 2,6-Pyrazinediamine, 3-(3-amino-1,2,4-oxadiazol-5-yl)-5-chloro-
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-4-(4-phenoxyphenyl)piperazin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233153; BDBM50009210
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
Amino(picolinamido)methaniminium chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911973
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
N-[4-(2-Aminoethoxy)phenyl]imidazo[1,2-a]pyridin-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3741860; BDBM50499910
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[12] | |||
| Compound Name |
Benzoylguanidine hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911971; 1-benzoylguanidine hydrochloride; N-benzoylguanidine hydrochloride; SCHEMBL6274668; NSC68221; NSC-68221; AKOS024339530; MCULE-7802483170; AMINO(BENZAMIDO)METHANIMINIUM CHLORIDE
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[4-(2-carbamoylphenoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238378; BDBM50009204
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-Amino-23-benzyl-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-26-[3-(diaminomethylideneamino)propyl]-11-(1H-indol-3-ylmethyl)-17,29-dimethyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3735263; BDBM50499238
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[30] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(3-sulfamoylphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238368; BDBM50009177
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
N-(Diaminomethylidene)-1H-imidazole-5-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911977
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
3-Amino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909778
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
3-(4-Amidinophenyl)-2-[[[(4-amidinophenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL135815; BDBM50067522
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[46] | |||
| Compound Name |
2-[[6-Amino-3-chloro-5-(diaminomethylidenecarbamoyl)pyrazin-2-yl]amino]ethanesulfonic acid;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909784
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
N-(Diaminomethylidene)pyrazine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911974
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
3-(3-Amidinophenyl)-2-[[[(4-cyanophenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL135998; BDBM50067524
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[46] | |||
| Compound Name |
(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-Amino-11,23-dibenzyl-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-26-[3-(diaminomethylideneamino)propyl]-17,29-dimethyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3735513; BDBM50499241
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[30] | |||
| Compound Name |
2-[[6-Amino-3-chloro-5-(diaminomethylidenecarbamoyl)pyrazin-2-yl]amino]ethyl-ethoxyphosphinic acid;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909789
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
Vaborbactam
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
RPX-7009; RPX7009; UNII-1C75676F8V; CHEMBL3317857; 1C75676F8V; Vaborbactam [INN]; RPX 7009; Vaborbactam. RPX7009; Vaborbactam (USAN/INN); Vaborbactam [USAN:INN]; SCHEMBL620289; GTPL10871; Vabomere (vaborbactam + meropenem); EX-A2589; BDBM50089084; MFCD28502176; AKOS032961376; CS-6445; DB12107; SB17184; compound 9f [PMID: 25782055]; NCGC00510003-01; HY-19930; D10998; Q27252228
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[47] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(3-carbamoyl-4-phenoxyphenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238379; BDBM50009205
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
5,6-Dichloro-N-(diaminomethylidene)pyridine-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911975
Click to Show/Hide
|
||||
| Activity |
IC50 = 1000000 nM
|
[8] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(3-carbamoylphenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238369; BDBM50009178
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[3-carbamoyl-4-(pyridin-4-ylmethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233150; BDBM50009206
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
3-(3-Amidinophenyl)-2-[[[(4-amidinophenylsulfonyl)amino]acetyl]amino]propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL133027; BDBM50067523; 2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetylamino]-3-(3-carbamimidoyl-phenyl)-propionic acid
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[46] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-methoxyphenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238363; BDBM50009172
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
N-Methyl-2-[[[[(2-naphthyl)sulfonyl]amino]acetyl]amino]-3-[3-(diaminomethyl)phenyl]propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL346222; BDBM50072848; 3-(3-Diaminomethyl-phenyl)-N-methyl-2-[2-(naphthalene-2-sulfonylamino)-acetylamino]-propionamide
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[15] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-carbamoylphenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238366; BDBM50009175
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-propylphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238364; BDBM50009173
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-[4-(pyridin-4-ylmethoxy)phenyl]imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238376; BDBM50009202
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
(3R,8S,11S,14S,17S,20S,23S,26S,29S,32S)-11-(4-Acetamidobutyl)-3-amino-23-benzyl-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-26-[3-(diaminomethylideneamino)propyl]-17,29-dimethyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3736473; BDBM50499242
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[30] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[4-(2-amino-2-oxoethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238372; BDBM50009197
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
[[6-Amino-3-chloro-5-(diaminomethylidenecarbamoyl)pyrazin-2-yl]amino]methylphosphonic acid;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909786
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(3-cyanophenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238370; BDBM50009179
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
N-[(1S)-5-Amino-1-cyanopentyl]-7-methyl-6-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]pyrrolo[2,3-d]pyrimidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3238361; BDBM50009170
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
Amino(nicotinamido)methaniminium chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1911972
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
3-(4-Amidinophenyl)-2-[[[(4-cyanophenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL135198; BDBM50067530
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[46] | |||
| Compound Name |
(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-Amino-29-(4-aminobutyl)-11,23-dibenzyl-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-26-[3-(diaminomethylideneamino)propyl]-17-methyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3735217; BDBM50499237
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[30] | |||
| Compound Name |
N-[1-(Piperidinocarbonyl)-2-[4-(diaminomethyl)phenyl]ethyl]-2-[(2-naphthylsulfonyl)amino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL346607; BDBM50072840
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[15] | |||
| Compound Name |
3-(4-Amidinophenyl)-2-[[[(4-thiocarbamoylphenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL137311; BDBM50067527
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[46] | |||
| Compound Name |
5-Amino-6-bromo-N-(diaminomethylidene)pyrazine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1909779
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[8] | |||
| Compound Name |
3-(4-Guanidinophenyl)acrylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL7330221; CHEMBL1160767
Click to Show/Hide
|
||||
| Activity |
Ki = 1318256.74 nM
|
[13] | |||
| Compound Name |
Methyl 4-[(diaminomethylidene)amino]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Benzoic acid,4-[(aminoiminomethyl)amino]-, methyl ester; methyl 4-amino(immino)methylaminobenzoate; ACMC-20mpy6; SCHEMBL4066290; Methyl 4-carbamimidamidobenzoate; CHEMBL1160765; CTK4B3012; DTXSID70559217; 4-Guanidinobenzoic acid methyl ester; ZINC26751139; 4-Guanidino-benzoic Acid Methyl Ester; AKOS006336786; methyl 4-(diaminomethylideneamino)benzoate; Benzoic acid, 4-[(aminoiminomethyl)amino]-, methyl ester
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| Activity |
Ki = 1448771.85 nM
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[13] | |||
| Compound Name |
4-[4-(4-Biphenylyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL418023; SCHEMBL6925000; BDBM50099899; 4-(4-Biphenyl-4-yl-thiazol-2-yl)-5-methylsulfanyl-thiophene-2-carboxamidine; 5-methylsulfanyl-4-[4-(4-phenylphenyl)-1,3-thiazol-2-yl]thiophene-2-carboximidamide
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| Activity |
Ki = 1740000 nM
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[27] | |||
| Compound Name |
Chembl4127452
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Investigative | Compound Info | ||
| Synonyms |
BDBM50272220
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| Activity |
IC50 > 1946000 nM
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[19] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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