Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T18639 | Target Info | |||
| Target Name | Heparin-binding growth factor 1 (FGF1) | ||||
| Synonyms |
HBGF-1; Fibroblast growth factor 1; FGFA; FGF-1; Endothelial cell growth factor; ECGF-beta; ECGF; Beta-endothelial cell growth factor; Acidic fibroblast growth factor; AFGF
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| Target Type | Clinical trial Target | ||||
| Gene Name | FGF1 | ||||
| Biochemical Class | Growth factor | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(2S,3R,4S,5S,6S)-3-[(2S,3S,4S,5R,6S)-3-Amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[(2S,3R,4S,5S,6S)-5-amino-4-hydroxy-2-(hydroxymethyl)-6-[(2S,3R,4S,5S,6S)-4,5,6-trihydroxy-2-propoxycarbonyloxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxyoxane-2-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL403403; BDBM50374509
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| Activity |
IC50 = 290000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Design, synthesis, FGF-1 binding, and molecular modeling studies of conformationally flexible heparin mimetic disaccharides. Bioorg Med Chem Lett. 2008 Jan 1;18(1):344-9. | ||||
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