Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T20585 | Target Info | |||
| Target Name | Signal transducer and activator of transcription 6 (STAT6) | ||||
| Synonyms |
IL-4 Stat
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| Target Type | Literature-reported Target | ||||
| Gene Name | STAT6 | ||||
| Biochemical Class | Transcription factor | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
[2-[[(2S)-6-Amino-1-[(2S)-2-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl]-1-benzofuran-5-yl] dihydrogen phosphate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3740751; BDBM50499615
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| Activity |
IC50 = 89600 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity. J Med Chem. 2015 Nov 25;58(22):8970-84. | ||||
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