Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T21460 | Target Info | |||
| Target Name | Bcl-2-binding component 3 (BBC3) | ||||
| Synonyms |
p53 upregulated modulator of apoptosis; p53 up-regulated modulator of apoptosis; PUMA; JFY1; JFY-1; Bcl2binding component 3
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| Target Type | Literature-reported Target | ||||
| Gene Name | BBC3 | ||||
| Biochemical Class | B-cell lymphoma Bcl-2 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
7-(2-Ethoxyquinolin-3-yl)-2-methoxy-3-(2-methoxy-5-propan-2-ylquinolin-7-yl)-5-propan-2-ylquinoline
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1253485
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| Activity |
IC50 = 54000 nM
|
[1] | |||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
2-Methoxy-3-[2-methoxy-5-(2-methylpropyl)quinolin-7-yl]-5-propan-2-ylquinoline
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254426
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| Activity |
IC50 > 1000000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis and biological activities of new di- and trimeric quinoline derivatives. Bioorg Med Chem. 2010 Oct 1;18(19):7132-43. | ||||
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