Target Poor or Non Binder(s) Information
Target General Information | Top | ||||
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Target ID | T31595 | Target Info | |||
Target Name | Influenza Neuraminidase (Influ NA) | ||||
Synonyms |
STNA; NEU1; NANase; N-acylneuraminate glycohydrolase; Influ Sialidase
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Target Type | Successful Target | ||||
Gene Name | Influ NA | ||||
Biochemical Class | Glycosylase | ||||
UniProt ID |
Poor Binders of This Target (in total, 5 binders) | Download | Top | |||
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Compound Name |
3,4-Dihydroxycinnamic Acid
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Phase 4 | Compound Info | ||
Synonyms |
Caffeic acid; caffeic acid; 3,4-Dihydroxycinnamic acid; 331-39-5; 3-(3,4-dihydroxyphenyl)acrylic acid; 501-16-6; (E)-3-(3,4-dihydroxyphenyl)acrylic acid; 3,4-Dihydroxybenzeneacrylic acid; (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid; trans-caffeic acid; trans-Caffeate; 3,4-Dihydroxy-trans-cinnamate; 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-; Cinnamic acid, 3,4-dihydroxy-; 3-(3,4-Dihydroxyphenyl)propenoic acid; UNII-U2S3A33KVM; 3-(3,4-Dihydroxyphenyl)-2-propenoic acid; 4-(2-Carboxyethenyl)-1,2-dihydroxybenzene
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Activity |
IC50 ~ 100000 nM
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[1] | |||
Compound Name |
Mesalamine
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Investigative | Compound Info | ||
Synonyms |
5-Aminosalicylic acid; Mesalazine; 5-Amino-2-hydroxybenzoic acid; Asacol; Pentasa; Claversal; Canasa; 5-ASA; Salofalk; Rowasa; m-Aminosalicylic acid; Mesasal; Lialda; Benzoic acid, 5-amino-2-hydroxy-; Fisalamine; Lixacol; Apriso; p-Aminosalicylsaeure; Asacolitin; Mesalazina; Mesalazinum; sfRowasa; 5-amino-2-hydroxy-benzoic acid; Asacol HD; 5-Amino Salicylic Acid; SALICYLIC ACID, 5-AMINO-; MFCD00007877; 2-Hydroxy-5-aminobenzoic acid; 3-carboxy-4-hydroxyaniline; UNII-4Q81I59GXC; NSC 38877; MAX-002; MLS001424012; 4Q81I59GXC; NSC-38877; NCGC00016344-03; Mesalazinum [Latin]; SMR000145728; DSSTox_CID_4506; DSSTox_RID_77435; DSSTox_GSID_24506; 5-Aminosalicylic acid, 99%; Mesalazina [Spanish]; p-Aminosalicylsaeure [German]; Mesavancol; Delzicol; Mesavance; Mezavant; Iialda; Mesalazine MMX; Mezavant XL; Mesalamine (USP); Pentasa (TN); 5-Aminosalicylicacid; Salofalk Granu-Stix; Apriso (TN); Asacol (TN); Canasa (TN); Lialda (TN); Rowasa (TN); CCRIS 7334; SR-01000763486; Mesalamine [USAN:USP]; EINECS 201-919-1; BRN 2090421; AI3-15564; 5-Aminosalicylic Acid, Purified; HSDB 7512; AJG-501; SPD 476; SPD-476; SPD-480; Mesalamine (TN); Delzicol (TN); Sfrowasa (TN); Mesalazine [INN]; mesalamine (USAN); Mesalamine (Lialda); 5-aminosalicylic_acid; MD-0901; 5-Aminosalicyclic acid; 5-amino-salicylic acid; PubChem17623; Mesalazine; ACMC-1BKFR; Prestwick0_001069; Prestwick1_001069; Prestwick2_001069; Prestwick3_001069; WLN: ZR DQ CVQ; Z-206; CHEMBL704; Mesalazine (JP17/INN); EC 201-919-1; cid_4075; Oprea1_847633; SCHEMBL31297; 3amino-6-hydroxybenzoic acid; BSPBio_001058; KBioGR_002425; KBioSS_002431; 4-14-00-02058 (Beilstein Handbook Reference); KSC448C0L; MLS000758287; 5-Aminosalicylic acid, 95%; 5-Aminosalicylic acid, tablet; ARONIS23914; BIDD:GT0811; 3-amino-6-hydroxybenzoic acid; SPBio_002969; BPBio1_001164; GTPL2700; ZINC1688; 5-Amino 2-hydroxy benzoic acid; DTXSID5024506; SCHEMBL18038934; 5-Aminosalicylic acid, >=99%; BDBM60918; CTK3E8105; KBio2_002425; KBio2_004993; KBio2_007561; KBio3_002904; cMAP_000045; HMS1571E20; HMS2051M21; HMS2090I09; HMS2098E20; HMS3393M21; HMS3649K15; HMS3651M15; HMS3715E20; Pharmakon1600-01505993; BCP05326; KS-00000CC5; KS-000048PQ; NSC38877; Tox21_110384; Tox21_201610; Tox21_303125; 5-?Aminosalicylic Acid (Mesalazine); ANW-39326; BBL013046; NSC759301; s1681; SBB052617; STK301678; AKOS000118959; Tox21_110384_1; AC-2764; BCP9000175; CCG-100829; DB00244; HS-0100; LS11426; MCULE-5752745805; NC00079; NSC-759301; NCGC00016344-01; NCGC00016344-02; NCGC00016344-04; NCGC00016344-05; NCGC00016344-07; NCGC00090934-01; NCGC00090934-02; NCGC00257142-01; NCGC00259159-01; 5-amino-2-hydroxobenzoic acid monohydrate; AK-72925; BP-13074; BR-72925; HY-15027; SC-15695; SY002854; 5-Aminosalicylic acid, analytical standard; ST4109571; A0317; AB00374979; AM20060091; FT-0619950; SW197303-4; 1764-EP2272825A2; 1764-EP2275420A1; C07138; D00377; M-7246; 24215-EP2289518A1; 24215-EP2295053A1; 24215-EP2295409A1; 24215-EP2314574A1; 24215-EP2314590A1; 90701-EP2371811A2; AB00374979-09; AB00374979-10; AB00374979_11; AB00374979_12; Q412479; Q-201355; SR-01000763486-3; SR-01000763486-4; SR-01000763486-9; Z57127471; F1918-0003
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Activity |
IC50 ~ 100000 nM
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[1] | |||
Compound Name |
1-Hydroxy-2-naphthoic acid
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Investigative | Compound Info | ||
Synonyms |
1-hydroxynaphthalene-2-carboxylic acid; 1-Naphthol-2-carboxylic acid; 2-Carboxy-1-naphthol; 2-Naphthalenecarboxylic acid, 1-hydroxy-; 1-HYDROXY-2-NAPHTHALENECARBOXYLIC ACID; UNII-U8LZ3R07L8; 2-Naphthoic acid, 1-hydroxy-; MFCD00003960; alpha-Hydroxynaphthoic acid; CHEMBL229299; U8LZ3R07L8; 1-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID; 1-Hydroxy-2-naphthoic acid, 98%; Xinafoic acid; 1-Hydroxy-2-naphthoicacid; NSC 3717; EINECS 201-674-0; CARBOXYNAPHTHOL; LDHA Inhibitor, 5; a-Hydroxynaphthoic acid; PubChem18787; AI3-28524; ACMC-209q9y; bmse000689; C03203; 7-Naphthol-2-carboxaldehyde; Oprea1_291089; SCHEMBL25244; .alpha.-Hydroxynaphthoic acid; 1 -hydroxy-2-naphthoic acid; KSC448K1P; RARECHEM AL BE 0359; DTXSID5058937; CTK3E8517; ZINC37856; NSC3717; HMS1719F05; hydroxynaphthalene-2-carboxylic acid; NSC-3717; ANW-38324; BBL027444; BDBM50219487; LABOTEST-BB LT00452757; LABOTEST-BB LT03329884; s6364; SBB057752; STL373496; AKOS001080081; 2-Naphthoic acid, 1-hydroxy- (8CI); AS03283; CS-W016819; FS-3779; HY-W016103; MCULE-9774378658; MP-2147; 1-hydroxy-2-naphthalene carboxylic acid; 1-Hydroxynaphthalenecarboxylic acid-(2); 1-oxidanylnaphthalene-2-carboxylic acid; KS-0000015L; 1-Hydroxy-2-naphthoic acid, >=97.0%; AC-13237; AK130464; BP-12641; SC-43863; ST053519; SY007524; DB-056929; FT-0607923; W-104066; Q27104334; Z56347239; F2191-0001
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Activity |
IC50 ~ 100000 nM
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[1] | |||
Compound Name |
3,4-Methylenedioxycinnamic acid
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Investigative | Compound Info | ||
Synonyms |
3,4-(METHYLENEDIOXY)CINNAMIC ACID; Methylenedioxycinnamic acid; UNII-X8H0WPJ08Y; (2e)-3-(1,3-benzodioxol-5-yl)acrylic acid; 3-(1,3-benzodioxol-5-yl)acrylic acid; 3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid; (E)-3-(1,3-benzodioxol-5-yl)prop-2-enoic acid; X8H0WPJ08Y; (2E)-3-(2H-1,3-benzodioxol-5-yl)prop-2-enoic acid; CHEMBL1173153; 3,4-Methylenedioxy Cinnamic Acid; MFCD00005837; 2-Propenoic acid, 3-(1,3-benzodioxol-5-yl)-; 3-(1,3-benzodioxol-5-yl)-2-propenoic acid; 2-Propenoic acid, 3-(1,3-benzodioxol-5-yl)-, (2E)-; (E)-3-(benzo[d][1,3]dioxol-5-yl)acrylic acid; Acetic acid, piperonylidene-; (2E)-3-(1,3-benzodioxol-5-yl)prop-2-enoic acid; 3,4-(Methylenedioxy)cinnamic acid, predominantly trans; 3-benzo[1,3]dioxol-5-yl-acrylic acid; 3,4-Methylenedioxybenzene-3-acrylic acid; 3-(3,4-Methylenedioxyphenyl)propenoic acid; piperonyl acrylic acid; PubChem8286; Cinnamic acid, 3,4-(methylenedioxy)-; 3-Piperonylacrylic Acid; SCHEMBL79427; 3,4-methylendioxycinnamic acid; 2-Propenoic acid, 3-(1,3-benzodioxol-5-yl)-, (E)-; 1,3-Benzodioxole-5-acrylic acid; HMS1397A21; ZINC152476; ALBB-011737; BBL012089; BDBM50486070; SBB042499; STK020097; AKOS000120493; CS-W010709; JS-3011; NCGC00182231-01; 3-(1,3-Benzodioxol-5-yl)propenoic acid; SC-02744; Cinnamic acid, 3,4-(methylenebis(oxy))-; 3-(3,4-methylenedioxyphenyl) acrylic acid; AB0017165; (e)-3-benzo[1,3]dioxol-5-yl-acrylic acid; BB 0221182; M0634; R1130; ST45026880; [(5-Bromo-1-pyrazolyl)sulfonyl]dimethylamine; 3,4-(Methylenedioxy)cinnamic acid, pred.trans; C18077; 373M800; CS-002/03843060; W-107380; Q27155410; F2191-0041; (2E)-3-(2H-benzo[d]1,3-dioxolen-5-yl)prop-2-enoic acid; 3,4-(Methylenedioxy)cinnamic acid, predominantly trans, 99%; (2E)-3-(2H-benzo[3,4-d]1,3-dioxolen-5-yl)prop-2-enoic acid
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Activity |
IC50 ~ 100000 nM
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[1] | |||
Compound Name |
Chembl4175602
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Investigative | Compound Info | ||
Synonyms |
BDBM50413055
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Activity |
IC50 ~ 100000 nM
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[2] |
References | Top | ||||
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REF 1 | Enhanced anti-influenza agents conjugated with anti-inflammatory activity. J Med Chem. 2012 Oct 11;55(19):8493-501. | ||||
REF 2 | Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses. Eur J Med Chem. 2018 Jun 25;154:314-323. |
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