Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T40491 | Target Info | |||
| Target Name | Serine/threonine PP2A-alpha (PPP2CA) | ||||
| Synonyms |
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; Replication protein C; RP-C; PP2A-alpha
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| Target Type | Clinical trial Target | ||||
| Gene Name | PPP2CA | ||||
| Biochemical Class | Phosphoric monoester hydrolase | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(2S,4R,4As,6R,8aR)-2-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,2'-oxolane]-4-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL158922; BDBM50097635
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| Activity |
IC50 > 1000000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Importance of the C28-C38 hydrophobic domain of okadaic acid for potent inhibition of protein serine-threonine phosphatases 1 and 2A. Bioorg Med Chem Lett. 2001 Mar 12;11(5):647-9. | ||||
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