Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T43920 | Target Info | |||
| Target Name | Carbonic anhydrase (CA) | ||||
| Synonyms |
Carbonate dehydratase
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| Target Type | Successful Target | ||||
| Gene Name | NO-GeName | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 3 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
2-[1-[5-(1,1-Dicyanoprop-1-en-2-yl)-3-methyl-4-phenylthieno[2,3-b]thiophen-2-yl]ethylidene]propanedinitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3360801; BDBM50028012
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| Activity |
IC50 = 441720 nM
|
[1] | |||
| Compound Name |
Methanesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
Methylsulfonamide; Methanesulphonamide; Methane sulfonamide; methyl sulfonylamine; methansulfonamid; CH5NO2S; methyl sulfonamide; aminosulfane dioxide; MFCD00007940; Methanesulfonamide, 98%; UNII-98YB2P6NHR; 98YB2P6NHR; CHEMBL305268; CH3SO2NH2; mesylamine; methansulfonamide; methansulphonamide; methylsulphonamide; methyl-sulfonamide; methylsulfonylamine; NSC 271; methane-sulfonamide; methyl sulphonamide; methane sulphonamide; EINECS 221-553-6; methanesulfonyl amine; methanesulfonimidic acid; H2NSO2Me; MeSO2NH2; ACMC-209hmq; AI3-51925; methanesulfonic acid amide; methansulphonic acid amide; methanesulphonic acid amide; KSC223M4J; NSC271; DTXSID3062865; CTK1C3644; HNQIVZYLYMDVSB-UHFFFAOYSA-; NSC-271; CS([N])(=O)=O; STR04982; ANW-27120; BDBM50044318; ZINC43781235; AKOS000150477; CS-W020062; MCULE-3286513976; Methanesulfonamide, >=97.0% (CHN); KS-000001C1; AK101074; BP-10673; SC-15857; SY001366; DB-002791; FT-0628286; M0915; AZ0001-0350; 44M090; M-7404; J-018431; J-521694; Z54080282; F0001-0946
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| Activity |
IC50 = 1000000 nM
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[2] | |||
| Compound Name |
Ethanesulfonamide
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|
Investigative | Compound Info | ||
| Synonyms |
Ethanesulfonic acid amide; CHEMBL69291; MFCD03265410; ethansulfonamid; ethyl sulfonamide; ethanesulphonamide; ethane sulfonamide; ethyl sulphonamide; NSC87899; NSC 87899; ethanesulfonimidic acid; methylmethanesulfonamide; d-ornithinehydrochloride; EtSO2NH2; methyl-methanesulfonamide; SCHEMBL28038; DTXSID9061752; CTK0H6678; ZINC4255681; ANW-50548; BDBM50044315; NSC-87899; AKOS000147712; CS-W003034; KS-00000B81; AK-46734; AS-17321; BR-46734; SC-18888; SY016774; DB-021484; FT-0693274; EN300-75234; 520E703; J-008881; J-520439; Z54886646
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| Activity |
IC50 = 1000000 nM
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[2] | |||
| References | Top | ||||
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| REF 1 | Substituted thieno[2,3-b]thiophenes and related congeners: Synthesis, -glucuronidase inhibition activity, crystal structure, and POM analyses. Bioorg Med Chem. 2014 Dec 1;22(23):6715-6725. | ||||
| REF 2 | Sulfonylmethanesulfonamide inhibitors of carbonic anhydrase. J Med Chem. 1993 Jul 23;36(15):2134-41. | ||||
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