Target Poor or Non Binder(s) Information
Target General Information | Top | ||||
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Target ID | T47885 | Target Info | |||
Target Name | Protein kinase D (PRKD1) | ||||
Synonyms |
nPKC-mu; nPKC-D1; Serine/threonine-protein kinase D1; Protein kinase C mu type; PRKCM; PKD1; PKD
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Target Type | Literature-reported Target | ||||
Gene Name | PRKD1 | ||||
Biochemical Class | Kinase | ||||
UniProt ID |
Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
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Compound Name |
aloisine A
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Investigative | Compound Info | ||
Synonyms |
ALOISINE A; 4-(7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol; 496864-16-5; RP107; 6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE; CHEMBL75680; 7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine; RP-107; ALH; 4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol; 1ung; SCHEMBL80147; BDBM7377; GTPL5924; AC1NS169; 4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)-phenol; CHEBI:93641; CTK8D4068; DTXSID30416115; HMS3229A14; RM-39; BCP26893; ZINC2540737; ACT06534; IN1539; HSCI1_000219; MFCD04973541; AKOS005145972; CCG-206814; DB07364; RTC-063070; AJ-39131
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Activity |
IC50 ~ 100000 nM
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[1] | |||
Compound Name |
3,4,5,10-Tetrahydro-7-hydroxy-azepino[3,4-b]indol-1(2H)-one
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Investigative | Compound Info | ||
Synonyms |
CHEMBL1672570; SCHEMBL9920629; BDBM50336959; 7-hydroxy-3,4,5,10-tetrahydro-2H-azepino[3,4-b]indol-1-one
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Activity |
IC50 ~ 50000 nM
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[2] |
References | Top | ||||
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REF 1 | Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects. J Med Chem. 2003 Jan 16;46(2):222-36. | ||||
REF 2 | Synthesis and Structure-Activity Relationships of Benzothienothiazepinone Inhibitors of Protein Kinase D. ACS Med Chem Lett. 2011 Feb 14;2(2):154-159. |
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