Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T52450 | Target Info | |||
| Target Name | Matrix metalloproteinase-1 (MMP-1) | ||||
| Synonyms |
Interstitial collagenase; Fibroblast collagenase; CLG
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|
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| Target Type | Successful Target | ||||
| Gene Name | MMP1 | ||||
| Biochemical Class | Peptidase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 288 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
US9206139, 4
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|
Patented | Compound Info | ||
| Synonyms |
CHEMBL3955404; SCHEMBL15692527; BDBM194645; US9206139, 4
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|
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| Activity |
IC50 = 56800 nM
|
[1] | |||
| Compound Name |
ARP100
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|
Investigative | Compound Info | ||
| Synonyms |
ARP 100; ARP-100
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
UK-356618
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|
Investigative | Compound Info | ||
| Synonyms |
UK 356618; 230961-08-7; CHEMBL117225; UK-356,618; SCHEMBL6437730; GTPL6528; CHEBI:94305; DTXSID50438778; MolPort-023-277-089; ZINC3924338; BDBM50097263; AKOS024458021; FT-0675728; PF 03890101; PF-03890101; UK-356618, > J-014983; BRD-K57011718-001-01-5; (R)-N*1*-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide
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| Activity |
IC50 = 51000 nM
|
[2] | |||
| Compound Name |
RXP470.1
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|
Investigative | Compound Info | ||
| Synonyms |
RXP470.1; CHEMBL507420; N-[(2s)-3-[(S)-(4-Bromophenyl)(Hydroxy)phosphoryl]-2-{[3-(3'-Chlorobiphenyl-4-Yl)-1,2-Oxazol-5-Yl]methyl}propanoyl]-L-Alpha-Glutamyl-L-Alpha-Glutamine; R47; GTPL7812; BDBM50265078; (4S)-5-amino-4-((2S)-2-((2S)-3-((4-bromophenyl)(hydroxy)phosphoryl)-2-((3-(3''-chlorobiphenyl-4-yl)isoxazol-5-yl)methyl)propanamido)-4-carboxybutanamido)-5-oxopentanoic acid
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|
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| Activity |
Ki = 67000 nM
|
[2] | |||
| Compound Name |
2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL574589; 2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide
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|
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| Activity |
IC50 = 73000 nM
|
[3] | |||
| Compound Name |
5-(3'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL574666; SCHEMBL5613445; BDBM50300481; 5-(3''-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid
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| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
2-(2-(biphenyl-4-yl)ethylthio)acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL572980; 2-(2-(biphenyl-4-yl)ethylthio)acetic acid
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| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
2-(2-(biphenyl-4-yl)ethylsulfinyl)acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL572947; 2-(2-(biphenyl-4-yl)ethylsulfinyl)acetic acid
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| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
(+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL572982; (+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid; SCHEMBL5613354; ILGSIIFHQGOKKV-UHFFFAOYSA-N; BDBM50300465; 5-biphenyl-4-yl-3-hydroxy-pentanoic acid; 5-(biphenyl-4-yl)-3-hydroxypentanoic acid
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|
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| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL583588; SCHEMBL5613483; BDBM50300472; 5-(4''-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid
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|
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| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
5-(biphenyl-4-yl)-3-oxopentanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL572979; 5-(biphenyl-4-yl)-3-oxopentanoic acid
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| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
2-(2-(biphenyl-4-yl)ethylsulfonyl)acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL566511; 2-(2-(biphenyl-4-yl)ethylsulfonyl)acetic acid
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|
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| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
5-(biphenyl-4-yl)-3-methoxypentanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL583771; 5-(biphenyl-4-yl)-3-methoxypentanoic acid
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| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
N1,N3-bis(3-methoxybenzyl)isophthalamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL605201; N1,N3-bis(3-methoxybenzyl)isophthalamide; SCHEMBL5332068
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|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL575895; N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Cis-2-aminocyclohexylcarbamoylphosphonic acid
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|
Investigative | Compound Info | ||
| Synonyms |
cis-ACCP; cis-2-aminocyclohexylcarbamoylphosphonic acid; 777075-44-2; CHEMBL270083; SCHEMBL569075; C7H15N2O4P; CTK8E9417; MolPort-039-139-066; BDBM50234465; 1683AH; ZINC29134634
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|
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| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
N-Hydroxy-N-[2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-1-(2,2,5-trimethyl-[1,3]dioxolan-4-yl)-ethyl]-formamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306050; BDBM50108165
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|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(2R)-2-[(4-But-2-ynoxyphenyl)sulfonylamino]-3-[1-[(4-methoxyphenyl)methyl]indol-3-yl]propanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL499905; SCHEMBL3847951; BDBM50278942; D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-methoxybenzyl)-1H-indol-3-yl)propanoic acid
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|
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
2-Benzo[1,3]dioxol-5-ylmethyl-N*4*-hydroxy-N*1*-(2-hydroxy-indan-1-yl)-succinamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL115082; SCHEMBL6046197; BDBM50104972
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|
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| Activity |
Ki = 50000 nM
|
[8] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-3-isoquinolin-4-ylbenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098997; BDBM50444721
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|
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| Activity |
IC50 = 50000 nM
|
[9] | |||
| Compound Name |
4-[2-[Formyl(hydroxy)amino]-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropyl]benzoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221177
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|
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| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-1-hydroxyurea
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43026; BDBM50100910; N-{2-[(4''-cyano-1,1''-biphenyl-4-yl)oxy]ethyl}-N-hydroxyurea
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|
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
4-{3-(Formyl-hydroxy-amino)-4-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-butyl}-benzoic acid methyl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL78213; SCHEMBL7990364; BDBM50108136; methyl 4-[3-[formyl(hydroxy)amino]-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylbutyl]benzoate
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|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
3-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-ethylsulfamoyl]-5-methyl-hexanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL309794; BDBM50290159
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|
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| Activity |
Ki ~ 50000 nM
|
[12] | |||
| Compound Name |
N-Hydroxy-N-{3-morpholin-4-yl-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-propyl}-formamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL75189; SCHEMBL8000486; BDBM50108149; N-[2-[4-[4-(Trifluoromethoxy)phenoxy]phenylsulfonyl]-1-(2-morpholinoethyl)ethyl]-N-hydroxyformamide; N-hydroxy-N-[4-morpholin-4-yl-1-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylbutan-2-yl]formamide
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|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-(1,1':4',1''-Terbenzene-4-ylmethyl)-3-hydroxy-4-oxo-6-methyl-4H-pyran-2-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL489603; AM-6; SCHEMBL13208686; BDBM50264772; 3-Hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid ([1,1'';4'',1'''']terphenyl-4-ylmethyl)-amide
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|
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
N-{1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-N-hydroxy-formamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306276; SCHEMBL7998643; BDBM50108153
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|
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| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
N-Hydroxy-N-{1-methoxymethyl-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL73866; SCHEMBL7677334; BDBM50108156; N-[2-[4-[4-(Trifluoromethoxy)phenoxy]phenylsulfonyl]-1-(methoxymethyl)ethyl]-N-hydroxyformamide; N-hydroxy-N-[1-methoxy-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropan-2-yl]formamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
3-Hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid (biphenyl-4-ylmethyl)-amide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL255374; SCHEMBL8268658; BDBM50241504; N-(Biphenyl-4-ylmethyl)-3-hydroxy-4-oxo-6-methyl-4H-pyran-2-carboxamide; N-(biphenyl-4-ylmethyl)-3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[13] | |||
| Compound Name |
N-{[4-(But-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL527018; BDBM50279256; DB07233; Q27096457; D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-methyl-1H-indol-3-yl)propanoic acid
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(3S,4S)-3-(4-Phenoxybenzenesulfonamido)-4-mercaptopyrrolidine Hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380399; SCHEMBL1973277
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| Activity |
Ki = 50000 nM
|
[14] | |||
| Compound Name |
(R)-2-(4-Fluoro-3,5-dimethylphenylamino)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1269994; SCHEMBL4738506; BDBM50329265; (2R)-2-(4-fluoro-3,5-dimethylanilino)-6-[(4-fluorophenyl)methylamino]-N-hydroxyhexanamide
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| Activity |
Ki ~ 50000 nM
|
[15] | |||
| Compound Name |
(S)-2-(4-Fluoro-3,5-dimethylbenzyl)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1760324; SCHEMBL3436885; BDBM50340754; (2S)-2-[(4-fluoro-3,5-dimethylphenyl)methyl]-6-[(4-fluorophenyl)methylamino]-N-hydroxyhexanamide
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| Activity |
Ki ~ 50000 nM
|
[15] | |||
| Compound Name |
(2R,3R)-4-(2-(3-Chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL590343; SCHEMBL8217068; BDBM50309147
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| Activity |
Ki ~ 50000 nM
|
[16] | |||
| Compound Name |
(1R,2S,5R)-2-[2-[4-(4-Chlorophenyl)phenyl]ethylsulfanyl]-5-[(1,3-dioxoisoindol-2-yl)methyl]cyclopentane-1-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL340455; BDBM50131940
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| Activity |
IC50 = 50000 nM
|
[17] | |||
| Compound Name |
(2R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2012837; BDBM50379534
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| Activity |
Ki ~ 50000 nM
|
[15] | |||
| Compound Name |
Dipotassium;6-amino-2-[[2-[4-[3-(carboxylatomethylamino)-2-[[(2S,3S)-2-[[ethoxy(hydroxy)phosphoryl]amino]-3-methylpentanoyl]amino]-3-oxopropyl]phenoxy]acetyl]amino]hexanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1744412
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| Activity |
Ki = 50000 nM
|
[18] | |||
| Compound Name |
But-2-ynyl 6-oxo-1,6-dihydropyridine-2-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL254837; BDBM50227600
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|
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| Activity |
IC50 = 50000 nM
|
[19] | |||
| Compound Name |
N-Hydroxy-N-{1-(1-methyl-1H-indol-2-yl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL74812; BDBM50108133
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(2S)-2-[(4-Fluoro-3,5-dimethylphenyl)methyl]-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2010824; BDBM50379535
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| Activity |
Ki ~ 50000 nM
|
[15] | |||
| Compound Name |
2-[(4-But-2-ynoxyphenyl)sulfonylamino]-3-(5-methoxy-1H-indol-3-yl)propanoic Acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL497908; SCHEMBL3848351; BDBM50279257; 2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-methoxy-1H-indol-3-yl)propanoic acid; rac-2-(4-But-2-ynyloxy-benzenesulfonyl-amino)-3-(5-methoxy-1H-indol-3-yl)-propionic acid; 2-(4-BUT-2-YNYLOXY-BENZENESULFONYLAMINO)-3-(5-METHOXY-1H-INDOL-3-YL)-PROPIONIC ACID
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
N-{1-(2,2-Dimethyl-[1,3]dioxolan-4-ylmethyl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-N-hydroxy-formamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL306301; BDBM50108167
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-Hydroxy-N-[2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-1-(4-trifluoromethyl-phenyl)-ethyl]-formamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL74365; SCHEMBL7670979; BDBM50108139
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-Hydroxy-N-{1-(2-hydroxy-ethoxymethyl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL309329; SCHEMBL7990013; BDBM50108163
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| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
N-[2-[4-[4-(Trifluoromethoxy)phenoxy]phenylsulfonyl]-1-[(R)-tetrahydrofuran-2-yl]ethyl]-N-hydroxyformamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221178
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| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
N-Hydroxy-N-{4-morpholin-4-yl-4-oxo-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-butyl}-formamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306585; SCHEMBL8002034; BDBM50108134
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|
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| Activity |
IC50 = 50000 nM
|
[6] | |||
| Compound Name |
1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-3-hydroxyurea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL41928; BDBM50100898; N-{2-[(4''-cyano-1,1''-biphenyl-4-yl)oxy]ethyl}-N''-hydroxyurea
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
Pentyl 6-oxo-1,6-dihydropyridine-2-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL252326; BDBM50227593
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|
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| Activity |
IC50 = 50000 nM
|
[19] | |||
| Compound Name |
(R)-2-Dodecyl-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl)succinamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL59722; BDBM50290450; (R)-2-Dodecyl-N*4*-hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-succinamide
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| Activity |
IC50 = 50000 nM
|
[20] | |||
| Compound Name |
2-[(4-But-2-ynoxyphenyl)sulfonylamino]-3-(5-phenylmethoxy-1H-indol-3-yl)propanoic Acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL463395; SCHEMBL3850968; BDBM50279287; 3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid; rac-2-(4-But-2-ynyloxy-benzenesulfonyl-amino)-3-(5-benzyloxy-1H-indol-3-yl)-propionic acid; 2-(4-BUT-2-YNYLOXY-BENZENESULFONYLAMINO)-3-(5-BENZYLOXY-1H-INDOL-3-YL)-PROPIONIC ACID
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
N-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-N-hydroxyformamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL36615; SCHEMBL6261290; BDBM50100904; N-[2-(4''-Cyano-biphenyl-4-yloxy)-ethyl]-N-hydroxy-formamide
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
4-{3-(Formyl-hydroxy-amino)-4-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-butyl}-benzoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL78145; SCHEMBL8000432; BDBM50108143; 4-[3-[formyl(hydroxy)amino]-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylbutyl]benzoic acid
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-[1-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221179
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
(2R,3R)-N-(2-(4-Benzylthiophen-2-yl)ethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL602949; SCHEMBL8217850; BDBM50309154
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[16] | |||
| Compound Name |
N-Hydroxy-N-[2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl-1-[(4S,5S)-2,2,5-trimethyl-1,3-dioxolan-4-yl]ethyl]formamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2043424; BDBM50385607
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
N-Hydroxy-N-{3-hydroxy-2-hydroxymethyl-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-propyl}-formamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77874; SCHEMBL7673637; BDBM50108171
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-Hydroxy-N-{1-(tetrahydro-furan-2-yl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL75114; BDBM50108147
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[6] | |||
| Compound Name |
N-Hydroxy-N-{3-(4-methanesulfonyl-piperazin-1-yl)-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-propyl}-formamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL78052; SCHEMBL7990283; BDBM50108138
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[6] | |||
| Compound Name |
N-{2,3-Dihydroxy-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-propyl}-N-hydroxy-formamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL75164; BDBM50108151
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
CID 10874819
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2114138; SCHEMBL7429119; BDBM50024168
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[6] | |||
| Compound Name |
N-Hydroxy-N-{1-phenyl-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL307915; SCHEMBL7673120; BDBM50108170; N-hydroxy-N-[1-phenyl-2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylethyl]formamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-Hydroxy-N-[2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-1-(3,4,4-trimethyl-2,5-dioxo-imidazolidin-1-ylmethyl)-ethyl]-formamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77907; SCHEMBL7676418; BDBM50108145
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
Morpholin-4-ylcarbonylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97838; BDBM50146803
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[21] | |||
| Compound Name |
N-Hydroxy-N-{1-pyridin-2-yl-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL73928; BDBM50108155; N-[2-[4-[4-(Trifluoromethoxy)phenoxy]phenylsulfonyl]-1-(2-pyridyl)ethyl]-N-hydroxyformamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-[(3S,4S)-1-(6-Aminohexanoyl)-4-hydroxypyrrolidin-3-yl]-4-phenoxybenzenesulfonamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380404
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[14] | |||
| Compound Name |
(Isopropylamino)carbonylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97034; Isopropylcarbamoylphosphonic Acid; BDBM50146799
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[21] | |||
| Compound Name |
(Ethylamino)carbonylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94348; Ethylcarbamoylphosphonic Acid; SCHEMBL11569435; BDBM50146811
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[21] | |||
| Compound Name |
(2R)-2-(4-Fluoro-3,5-dimethylanilino)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2012836; BDBM50379536
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[15] | |||
| Compound Name |
(R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1760322; BDBM50340768
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[15] | |||
| Compound Name |
(4R)-3-[4-(4-Fluorophenoxy)phenyl]sulfonyl-N-hydroxy-1,3-thiazolidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957603; BDBM50366205
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[22] | |||
| Compound Name |
2-[[4-(4-Bromophenyl)phenyl]sulfonylamino]acetic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44898; SCHEMBL7870635; BDBM50084304; ZINC13803841; (4''-Bromo-biphenyl-4-sulfonylamino)-acetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[23] | |||
| Compound Name |
Secoisolariciresinol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(-)-Secoisolariciresinol; UNII-M8QRJ7JEJH; CCRIS 7790; M8QRJ7JEJH; EINECS 249-599-2; (2R,3R)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]butane-1,4-diol; CHEMBL368347; (2R,3R)-2,3-bis(4-hydroxy-3-methoxybenzyl)butane-1,4-diol; (R-(R*,R*))-2,3-Bis((4-hydroxy-3-methoxyphenyl)methyl)butane-1,4-diol; RR-secoisolariciresinol; (-) secoisolariciresinol; (+/-)-Secoisolariciresinol; 8R,8'R-secoisolariciresinol; MLS001424213; SCHEMBL12427083; CTK4C5737; DTXSID50183615; HMS2052G03; HMS2232J05; (2R*,3R*)-2,3-Bis(4-hydroxy-3-methoxybenzyl)-1,4-butanediol; HY-N6071; ZINC2020114; BDBM50240914; MFCD01075136; AKOS032948353; CCG-101074; DB12179; NC00324; NCGC00346838-01; Secoisolariciresinol, >=95.0% (HPLC); SMR000469212; LS-185231; CS-0032316; C18167; Q-100372; Q4413253; 2,3-Bis(4-hydroxy-3-methoxybenzyl)-1,4-butanediol, (-); (2R,3R)-2,3-bis[(4-hydroxy-3-methoxy-phenyl)methyl]butane-1,4-diol
Click to Show/Hide
|
||||
| Activity |
IC50 = 50120 nM
|
[24] | |||
| Compound Name |
2-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399685; BDBM50227554
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[19] | |||
| Compound Name |
(+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]propionic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL579068; BDBM50299067
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[3] | |||
| Compound Name |
(S)-3-Benzyloxy-N-methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL403340; SCHEMBL6954663; BDBM50241378
Click to Show/Hide
|
||||
| Activity |
Ki = 52000 nM
|
[25] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2R)-2-Aminopropanoyl]amino]-3-phenylpropanoyl]amino]-4-methyl-N-phenylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL434624; BDBM50043595
Click to Show/Hide
|
||||
| Activity |
IC50 = 52100 nM
|
[26] | |||
| Compound Name |
3-(3,4-Dimethoxyphenyl)-2-[(E)-3-phenylprop-2-enoyl]oxypropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333261; BDBM50429259
Click to Show/Hide
|
||||
| Activity |
IC50 = 53700 nM
|
[27] | |||
| Compound Name |
6-(4-Chloro-phenyl)-3-{2-cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-hexanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL420376; BDBM50101525
Click to Show/Hide
|
||||
| Activity |
Ki = 54954.09 nM
|
[28] | |||
| Compound Name |
N-[(2S,4S)-1-[4-[2-(2,5-Dimethylpyridin-3-yl)ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683459; BDBM50337737
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[29] | |||
| Compound Name |
3-[2-Cyclohexyl-1-(4-morpholin-4-yl-butylcarbamoyl)-ethylcarbamoyl]-6-p-tolyl-hexanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL307027; BDBM50101500; (R)-3-[(S)-2-Cyclohexyl-1-(4-morpholin-4-yl-butylcarbamoyl)-ethylcarbamoyl]-6-p-tolyl-hexanoic acid
Click to Show/Hide
|
||||
| Activity |
Ki = 55000 nM
|
[30] | |||
| Compound Name |
4-Cyano-N-(2-piperidin-1-yl-phenyl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97612; BDBM50283774; AKOS008412051
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[31] | |||
| Compound Name |
(2R)-3-(1-Benzothiophen-3-yl)-2-[[5-[2-(4-butylphenyl)ethynyl]thiophen-2-yl]sulfonylamino]-N-hydroxypropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1795860; BDBM50346801
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[32] | |||
| Compound Name |
Thiophen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254039; BDBM50227537
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[19] | |||
| Compound Name |
(2S)-2-[[4-(4-Bromophenyl)phenyl]sulfonylamino]-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43276; SCHEMBL4422490; BDBM50084284; 2-(4''-Bromo-biphenyl-4-sulfonylamino)-3-phenyl-propionic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[23] | |||
| Compound Name |
4-Benzylsulfanyl-2-(4''-bromo-biphenyl-4-sulfonylamino)-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL295871; BDBM50084298
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[23] | |||
| Compound Name |
3-[2-Cyclohexyl-1-(2-methoxycarbonyl-ethylcarbamoyl)-ethylcarbamoyl]-6-phenyl-hexanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL78047; BDBM50101507; (R)-3-[(S)-2-Cyclohexyl-1-(2-methoxycarbonyl-ethylcarbamoyl)-ethylcarbamoyl]-6-phenyl-hexanoic acid
Click to Show/Hide
|
||||
| Activity |
Ki = 57543.99 nM
|
[28] | |||
| Compound Name |
(2R,3Ar,7aR)-1-[2-[[4-[[4-chloro-3-[[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylacetyl]sulfamoyl]benzoyl]sulfamoyl]benzoyl]amino]-3-methylbutanoyl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL265769; BDBM50058473
Click to Show/Hide
|
||||
| Activity |
IC50 = 58000 nM
|
[33] | |||
| Compound Name |
2-Phenoxyethyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL438519; BDBM50227595
Click to Show/Hide
|
||||
| Activity |
IC50 = 59000 nM
|
[19] | |||
| Compound Name |
N-Hydroxy-2-nitrobenzene-1-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
N-Hydroxy-2-nitrobenzenesulfonamide; Hydroxysulfonamide 61; CHEMBL121501; SCHEMBL8224048; BDBM11380; CTK0J7177; DTXSID60635312; MFCD18072514; ZINC13813802; Benzenesulfonamide, N-hydroxy-2-nitro-
Click to Show/Hide
|
||||
| Activity |
Ki = 59000 nM
|
[34] | |||
| Compound Name |
N-Hydroxy-2-(N-isopropoxy-4-phenoxyphenylsulfonamido)-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561038; BDBM50294126
Click to Show/Hide
|
||||
| Activity |
IC50 = 59000 nM
|
[35] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-Aminopropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL265583; BDBM50043599
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[26] | |||
| Compound Name |
(2S)-N-[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL135857; BDBM50043579
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[26] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2R)-2-Aminopropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methyl-N-[(1R)-1-phenylethyl]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL132816; BDBM50043602
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[26] | |||
| Compound Name |
(S)-2-{4'-[(5-Iodo-4-methoxy-3-methyl-benzofuran-2-carbonyl)-amino]-biphenyl-4-sulfonylamino}-3-methyl-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL199241; SCHEMBL3606939; BDBM50173218
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[36] | |||
| Compound Name |
(2R)-2-Amino-N-[(2S)-1-[[(2S)-1-(benzylamino)-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339191; BDBM50043597
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[26] | |||
| Compound Name |
N-Hydroxy-2-[4-(3-fluorobenzyloxy)phenylsulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431016; BDBM50441223
Click to Show/Hide
|
||||
| Activity |
IC50 = 61000 nM
|
[37] | |||
| Compound Name |
(1R,2R,5S)-2-[(2,4-Dioxopyrido[1,2-a][1,3,5]triazin-3-yl)methyl]-5-[4-(4-methylsulfanylphenyl)phenyl]sulfanylcyclopentane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339610; BDBM50131955
Click to Show/Hide
|
||||
| Activity |
IC50 = 63000 nM
|
[17] | |||
| Compound Name |
(4S,5S)-4-Phenylsulfanyl-2-p-tolyl-5-vinyl-4,5-dihydro-oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL184472; BDBM50152630
Click to Show/Hide
|
||||
| Activity |
Ki = 64000 nM
|
[38] | |||
| Compound Name |
2-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253373; BDBM50227552
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[19] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-3-quinolin-5-ylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098998; BDBM50444720
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[9] | |||
| Compound Name |
N-Hydroxy-4-methylbenzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Benzenesulfonamide, N-hydroxy-4-methyl-; N-hydroxy-4-methylbenzene-1-sulfonamide; tosylhydroxylamine; N-Tosylhydroxylamine; N-hydroxy-4-methyl-benzenesulfonamide; Hydroxysulfonamide 58; ACMC-209djs; p-tolyl-N-hydroxysulfonamide; N-hydroxy-4-toluenesulfonamide; CHEMBL121559; SCHEMBL1832454; BDBM11377; CTK8B0907; DTXSID10435263; ANW-21830; MFCD11850835; ZINC13813791; AKOS015888649; MCULE-3823003338; SC-50302; DB-064280; CS-0068832; FT-0760726; V3581; A-3307
Click to Show/Hide
|
||||
| Activity |
Ki = 65000 nM
|
[34] | |||
| Compound Name |
6-Oxo-1,6-dihydro-pyridine-2-carboxylic acid 4-methyl-benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253801; BDBM50227586
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[19] | |||
| Compound Name |
(Hydroxyamino)(4-iodophenyl)sulfone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Hydroxysulfonamide 57; CHEMBL120934; SCHEMBL8229583; BDBM11376; ZINC5570003; AKOS024355469; N-hydroxy-4-iodobenzene-1-sulfonamide; MCULE-2099459518; ST50982751
Click to Show/Hide
|
||||
| Activity |
Ki = 66000 nM
|
[34] | |||
| Compound Name |
(S)-3-Cyclohexyl-N-methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL398703; SCHEMBL6958038; BDBM50241374; (2S)-3-cyclohexyl-N-methyl-2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)carbamoylamino]propanamide
Click to Show/Hide
|
||||
| Activity |
Ki = 67000 nM
|
[25] | |||
| Compound Name |
4-Phenoxybutyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253372; BDBM50227559
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[19] | |||
| Compound Name |
(1S,2R,5S)-2-[4-(4-Chlorophenyl)phenyl]sulfanyl-5-[(4-oxo-1,2,3-benzotriazin-3-yl)methyl]cyclopentane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339588; SCHEMBL7223120; BDBM50131953
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[17] | |||
| Compound Name |
3-Phenoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254038; BDBM50227574
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[19] | |||
| Compound Name |
(2S)-2-[(7,7-Dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl)methylsulfonylamino]-N-[(2S)-1-oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3142612
Click to Show/Hide
|
||||
| Activity |
Ki = 69000 nM
|
[39] | |||
| Compound Name |
3-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL252965; BDBM50227578
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[19] | |||
| Compound Name |
N-[(2S,4S)-1-[4-[2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683462; BDBM50337741
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 70000 nM
|
[29] | |||
| Compound Name |
(Dibutylamino)carbonylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL96438; BDBM50146804
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[21] | |||
| Compound Name |
Hydroxysulfonamide 50
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL122109; BDBM11369; 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-N-hydroxyoctane-1-sulfonamide
Click to Show/Hide
|
||||
| Activity |
Ki = 70000 nM
|
[34] | |||
| Compound Name |
(1R,2S,5R)-2-[2-[4-(4-Chlorophenyl)phenyl]ethylsulfanyl]-5-[(4-oxo-1,2,3-benzotriazin-3-yl)methyl]cyclopentane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339137; BDBM50131954
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 70000 nM
|
[17] | |||
| Compound Name |
2,5-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399304; BDBM50227547
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[19] | |||
| Compound Name |
N-[(2S,4S)-1-[4-[2-(2-Chloro-4-methylsulfonylphenyl)ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683464; BDBM50337734
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 70000 nM
|
[29] | |||
| Compound Name |
Piperidin-1-ylcarbonylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL95068; SCHEMBL11749901; BDBM50146802
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[21] | |||
| Compound Name |
(1R,2S,5R)-2-[4-(4-Chlorophenyl)phenyl]sulfanyl-5-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]cyclopentane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126712; BDBM50131949
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[17] | |||
| Compound Name |
4-Chloro-N-hydroxybenzene-1-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
N-(p-chlorobenzenesulfonyl)hydroxylamine; 4-chloro-N-hydroxybenzenesulfonamide; NSC528513; Hydroxysulfonamide 55; CHEMBL301469; SCHEMBL5194625; BDBM11374; DTXSID10326460; ZINC1607221; 4-Chloro-N-hydroxy-benzenesulfonamide; NSC-528513; DS-014970
Click to Show/Hide
|
||||
| Activity |
Ki = 71000 nM
|
[34] | |||
| Compound Name |
4-Bromo-N-hydroxybenzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
p-Bromo-N-hydroxybenzenesulfonamide; Benzenesulfonamide, p-bromo-N-hydroxy-; 4-bromo-N-hydroxybenzene-1-sulfonamide; N-(p-bromobenzenesulfonyl)hydroxylamine; BRN 2645335; Hydroxysulfonamide 56; p-Bromobenzenesulfonhydroxamide; CHEMBL123404; SCHEMBL8229526; BDBM11375; CTK8H4740; DTXSID90941675; N-Hydroxy-p-bromobenzenesulfonamide; ZINC6093148; 4-Bromo-N-hydroxybenzenesulfonamide #
Click to Show/Hide
|
||||
| Activity |
Ki = 71000 nM
|
[34] | |||
| Compound Name |
(2S)-2-(Naphthalen-2-ylsulfonylamino)-N-[(2S)-1-oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3142591
Click to Show/Hide
|
||||
| Activity |
Ki = 72000 nM
|
[39] | |||
| Compound Name |
Hydroxysulfonamide 49
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL332439; BDBM11368; 1,1,2,2,3,3,4,4,4-nonafluoro-N-hydroxybutane-1-sulfonamide
Click to Show/Hide
|
||||
| Activity |
Ki = 74000 nM
|
[34] | |||
| Compound Name |
N-(p-Fluorobenzenesulfonyl)hydroxylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-fluoro-N-hydroxybenzene-1-sulfonamide; Hydroxysulfonamide 54; CHEMBL332145; SCHEMBL2492594; BDBM11373; 4-fluoro-n-hydroxybenzenesulfonamide; N-Hydroxy-4-fluorobenzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
Ki = 74000 nM
|
[34] | |||
| Compound Name |
N-Hydroxy-2-[4-[4-(trifluoromethoxy)benzyloxy]phenylsulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431031; BDBM50441226
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[37] | |||
| Compound Name |
(2S)-N-[(2S)-1-Oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenyl-2-(quinolin-8-ylsulfonylamino)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3142613
Click to Show/Hide
|
||||
| Activity |
Ki = 74000 nM
|
[39] | |||
| Compound Name |
Naphthalen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253188; BDBM50227545
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[19] | |||
| Compound Name |
N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-indan-1-yl-succinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL323874; BDBM50104964
Click to Show/Hide
|
||||
| Activity |
Ki = 75000 nM
|
[8] | |||
| Compound Name |
6-Mercapto-pyridine-2-carboxylic acid biphenyl-3-ylmethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251426; BDBM50227601
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[19] | |||
| Compound Name |
3-Phenoxybenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL250069; BDBM50227575
Click to Show/Hide
|
||||
| Activity |
IC50 = 78000 nM
|
[19] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-4-quinolin-3-ylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098991; BDBM50444727
Click to Show/Hide
|
||||
| Activity |
IC50 = 78000 nM
|
[9] | |||
| Compound Name |
N-Hydroxybenzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Benzenesulfohydroxamic acid; Piloty's acid; Benzenesulfonamide, N-hydroxy-; Benzenesulphonohydroxamic acid; Benzsulfohydroxamic acid; Hydroxamic acid, benzsulfo-; N-(Phenylsulfonyl)hydroxylamine; Hydroxylamine, N-(phenylsulfonyl)-; UNII-C64L4UMH19; CHEMBL55310; C64L4UMH19; MFCD00025013; EINECS 209-973-8; N-Hydroxy-benzenesulfonamide; BRN 2257368; Benzenesulfohyd; piloty acid; BENZENESULFOHYDROXAMICACID; Hydroxysulfonamide 53; Hydroxyphenylsulfonamide; Benzenesulfhydroxamic acid; (hydroxyamino)phenylsulfone; C6H7NSO3; Benzenesulfonamide,N-hydroxy-; 4-11-00-00093 (Beilstein Handbook Reference); SCHEMBL184252; DTXSID4060521; BDBM11372; CTK5B0780; HMS3650A13; NSC45357; ZINC4284435; 1634AH; 7672AF; ANW-43953; NSC-45357; AKOS001139035; MCULE-1579584179; NE34189; VZ36592; AS-59127; ST50825041; SR-01000946758; SR-01000946758-1; Q27275238
Click to Show/Hide
|
||||
| Activity |
Ki = 79000 nM
|
[34] | |||
| Compound Name |
N-[(2S,4S)-4-(5-Fluoropyrimidin-2-yl)-2-methyl-1-[4-[2-[3-methyl-5-(trifluoromethyl)pyridin-2-yl]ethyl]piperidin-1-yl]sulfonylpentan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683463; BDBM50337740
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 79000 nM
|
[29] | |||
| Compound Name |
(2S)-2-(Naphthalen-1-ylsulfonylamino)-N-[(2S)-1-oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3142599
Click to Show/Hide
|
||||
| Activity |
Ki = 80000 nM
|
[39] | |||
| Compound Name |
Phenethylcarbamoylphosphonic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL24447; [(2-phenylethyl)amino]carbonylphosphonic acid; SCHEMBL13986851; BDBM50112446
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[21] | |||
| Compound Name |
Pentan-3-ylcarbamoylphosphonic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL318664; [(1-ethylpropyl)amino]carbonylphosphonic acid; BDBM50146808
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[21] | |||
| Compound Name |
4-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254448; BDBM50227563
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[19] | |||
| Compound Name |
3-Methoxybenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254406; BDBM50227568
Click to Show/Hide
|
||||
| Activity |
IC50 = 86000 nM
|
[19] | |||
| Compound Name |
Cinnamyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254657; BDBM50227587
Click to Show/Hide
|
||||
| Activity |
IC50 = 86000 nM
|
[19] | |||
| Compound Name |
(2S)-2-[[5-(Dimethylamino)naphthalen-1-yl]sulfonylamino]-N-[(2S)-1-oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3142608
Click to Show/Hide
|
||||
| Activity |
Ki = 87000 nM
|
[39] | |||
| Compound Name |
(S)-2-(Acetyl-methyl-amino)-N-hydroxy-3-(4-phenoxy-benzenesulfonyl)-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL92847; BDBM50105442
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[40] | |||
| Compound Name |
trans-2-Aminocyclohexylcarbamoylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL270296; SCHEMBL4854279; BDBM50372742; ZINC29134636; [(1R,2R)-2-aminocyclohexyl]carbamoylphosphonic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[41] | |||
| Compound Name |
(2r,3r)-4-[4-(2-Chlorophenyl)piperazin-1-Yl]-2,3-Dihydroxy-4-Oxo-N-(2-Thiophen-2-Ylethyl)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL605764; SCHEMBL8216976; BDBM50309132; Q27454292
Click to Show/Hide
|
||||
| Activity |
Ki ~ 90000 nM
|
[16] | |||
| Compound Name |
2,6-Difluorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL250058; BDBM50227531
Click to Show/Hide
|
||||
| Activity |
IC50 = 92000 nM
|
[19] | |||
| Compound Name |
(4S,5S)-2-Styryl-5-vinyl-4,5-dihydro-oxazole-4-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL186559; BDBM50152635
Click to Show/Hide
|
||||
| Activity |
Ki = 92000 nM
|
[38] | |||
| Compound Name |
4-{(5Z)-2,4-Dioxo-5-[(2E)-3-phenylprop-2-enylidene]-1,3-thiazolidin-3-yl}butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927184; HMS1425E10; BDBM50359722; ZINC15906851; AKOS001490556; IDI1_010429; ST50054937; 4-[5-((2E)-3-phenylprop-2-enylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]butanoic a cid
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[42] | |||
| Compound Name |
Benzenemethanesulfonamide, N-hydroxy-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Hydroxysulfonamide 52; N-Benzylsulfonylhydroxylamin; CHEMBL333122; N-hydroxyphenylmethanesulfonamide; SCHEMBL10656290; BDBM11371; N-hydroxy-1-phenylmethanesulfonamide
Click to Show/Hide
|
||||
| Activity |
Ki = 95000 nM
|
[34] | |||
| Compound Name |
3-Phenylpropyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL252523; BDBM50227542
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[19] | |||
| Compound Name |
N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(3-methoxy-benzyl)-succinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL114357; SCHEMBL6045948; BDBM50104970
Click to Show/Hide
|
||||
| Activity |
Ki = 95500 nM
|
[8] | |||
| Compound Name |
5-[4-(4-Acetylphenyl)phenyl]-3-hydroxypentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL584559; SCHEMBL5613397; BDBM50300471; 5-(4''-acetylbiphenyl-4-yl)-3-hydroxypentanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
3-Acetoxy-5-(biphenyl-4-yl)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL574445; SCHEMBL5694346; BDBM50300477; 3-acetyloxy-5-(4-phenylphenyl)pentanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
5-(4-(Dibenzo[b,d]furan-3-yl)phenyl)-3-hydroxypentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL575946; BDBM50300468
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
5-(4-(9H-Fluoren-2-yl)phenyl)-3-hydroxypentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL566512; BDBM50300469
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
5-(4''-(Benzyloxy)biphenyl-4-yl)-3-hydroxypentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL572926; BDBM50300466
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
3-Hydroxy-5-[4-(4-methylsulfanylphenyl)phenyl]pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL575320; SCHEMBL5613380; BDBM50300470; 3-hydroxy-5-(4''-(methylthio)biphenyl-4-yl)pentanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
3-Hydroxy-5-[4-(4-phenoxyphenyl)phenyl]pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL575947; SCHEMBL5613747; BDBM50300467; 3-hydroxy-5-(4''-phenoxybiphenyl-4-yl)pentanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 98000 nM
|
[4] | |||
| Compound Name |
4-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253172; BDBM50227538
Click to Show/Hide
|
||||
| Activity |
IC50 = 99000 nM
|
[19] | |||
| Compound Name |
Naphthalen-2-yl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251424; BDBM50227584
Click to Show/Hide
|
||||
| Activity |
IC50 = 99000 nM
|
[19] | |||
| Compound Name |
Thioacetic acid S-[(4S,5S)-2-(4-chloro-phenyl)-5-vinyl-4,5-dihydro-oxazol-4-yl] ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL184148; BDBM50152652
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[38] | |||
| Compound Name |
(R)-2-(N-Isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL575881; BDBM50299057; ZINC45289527
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL84969; BB-3554; SCHEMBL4956500; BDBM50104500; 2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((S)-1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[43] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-4-isoquinolin-4-ylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098992; BDBM50444726
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
(R)-3-((S)-1-((S)-2-Methoxy-1-phenylethylamino)-3,3-dimethyl-1-oxobutan-2-ylcarbamoyl)-6-(2-methylbiphenyl-4-YL)hexanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UK 370106; UK-370106; CHEMBL250266; SCHEMBL6449140; C35H44N2O5; ZINC3916209; 1503AB; BDBM50227718; AKOS016004936; HY-107639; CS-0029038; J-014984
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[44] | |||
| Compound Name |
(Methylamino)carbonylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97388; SCHEMBL12758377; BDBM50146809; AKOS006379972
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
Cyclohexanamine;3-methylbutylcarbamoylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1160686
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
N-Hydroxy-2-[[4-[(3-phenylphenyl)methoxy]phenyl]sulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431018; BDBM50441221
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[37] | |||
| Compound Name |
(E)-N-(4-Amino-2-methylquinolin-6-yl)-3-(2-methoxyphenyl)prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3099009; BDBM50444709
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
N-[(2S)-3-(4-Methoxyphenyl)-1-(methylamino)-1-oxopropan-2-yl]-4-methyl-2-[(2-sulfanylidene-1H-pyridin-3-yl)methyl]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL323285; BDBM50286125
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
(1R,2S,5R)-2-[4-(4-Chlorophenyl)phenyl]sulfonyl-5-[(4-oxo-1,2,3-benzotriazin-3-yl)methyl]cyclopentane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL341249; BDBM50131962
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-[(2S,4S)-1-[4-[2-(2,5-Dimethylpyridin-4-yl)ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683458; BDBM50337724
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
2-(2-Mercapto-benzyl)-4-methyl-pentanoic acid (2-oxo-azacyclotridec-3-yl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL103665; BDBM50286127
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(2-hydroxy-1,1-dimethylethyl)amino]methyl}-1,2,4-oxadiazol-5-yl)hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL229866; SCHEMBL5412113; BDBM50216829
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
2-[3-(4-Biphenylyloxymethyl)-4-oxo-4-(hydroxyamino)butyl]-3-oxo-2,3-dihydro-1,2-benzisothiazole 1,1-dioxide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL103442; SCHEMBL7224224; BDBM50096643; N-hydroxy-2-[(4-phenylphenoxy)methyl]-4-(1,1,3-trioxo-1,2-benzothiazol-2-yl)butanamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[47] | |||
| Compound Name |
4-Phenoxy-N-[(1R,2S)-2-sulfanylcyclopentyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380391; BDBM50433876
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[14] | |||
| Compound Name |
Prop-2-enyl 2-[(E)-3-(4-bromophenyl)prop-2-enoyl]oxy-3-(3,4-dimethoxyphenyl)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333284; BDBM50429236
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
3-(3,4-Dimethoxyphenyl)-2-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]oxypropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333272; BDBM50429247
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
Prop-2-enyl 3-(3,4-dimethoxyphenyl)-2-[(E)-3-(4-nitrophenyl)prop-2-enoyl]oxypropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333285; BDBM50429235
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
CID 50943150
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933882; BDBM50360393; (E)-2-(1H-benzimidazol-2-yl)-3-(5-thiophen-2-ylthiophen-2-yl)prop-2-enenitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[48] | |||
| Compound Name |
N-(2-Methyl-4-amino-6-quinolyl)-4-(6-quinolyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3099031; BDBM50444735
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2-(Biphenyl-4-ylmethylsulfanyl)-5-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-cyclopentanecarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL125104; BDBM50131952
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(R)-2-(4''-((4-(4-Fluorobenzoyl)phenoxy)methyl)biphenyl-4-ylsulfonamido)-3-methylbutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL468722; SCHEMBL13978744; BDBM50258875
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
(4S,5S)-2-(4-Chloro-phenyl)-5-vinyl-4,5-dihydro-oxazole-4-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL361034; BDBM50152648
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[38] | |||
| Compound Name |
(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL439012; SCHEMBL6178395; BDBM50216817
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
3-[1-(2-Carboxy-ethylcarbamoyl)-2-cyclohexyl-ethylcarbamoyl]-6-p-tolyl-hexanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306177; BDBM50101524; (R)-3-(((S)-1-(2-carboxyethylamino)-3-cyclohexyl-1-oxopropan-2-yl)carbamoyl)-6-p-tolylhexanoic acid; (R)-3-[(S)-1-(2-Carboxy-ethylcarbamoyl)-2-cyclohexyl-ethylcarbamoyl]-6-p-tolyl-hexanoic acid
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[30] | |||
| Compound Name |
(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3394285; SCHEMBL12425758; BDBM50140176; (E)-3-[4-(trifluoromethyl)phenyl]prop-2-enehydroxamic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[50] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-2-(4-phenylmethoxyphenoxy)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098987; BDBM50444732
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
(1R,2S,5R)-2-[2-[4-(4-Chlorophenyl)phenyl]ethylsulfonyl]-5-[(4-oxo-1,2,3-benzotriazin-3-yl)methyl]cyclopentane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127787; BDBM50131958
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
{2-[2-Cyclohexyl-1-(2-morpholin-4-yl-ethylcarbamoyl)-ethylcarbamoyl]-5-phenyl-pentyl}-phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306779; BDBM50101493
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[30] | |||
| Compound Name |
2-(4-Oxo-4H-benzo[d][1,2,3]triazin-3-ylmethyl)-5-(4-thiazol-2-yl-phenylsulfanyl)-cyclopentanecarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL125302; BDBM50131951
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(2R,3R)-4-[2-(3-Chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(4-pyrazol-1-ylphenyl)methyl]butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1779630; SCHEMBL8221083; BDBM50343959
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[51] | |||
| Compound Name |
Cyclooctylcarbamoylphosphonic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97709; (cyclooctylamino)carbonylphosphonic acid; BDBM50146798
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
(2R,3R)-4-[(2R)-2-(3-Chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1770629; SCHEMBL8224023; BDBM50342963
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[52] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-3-quinolin-3-ylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098996; BDBM50444722
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-6-(4-methoxy-phenyl)-hexanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL309067; BDBM50101521
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[28] | |||
| Compound Name |
Prop-2-enyl 3-(3,4-dimethoxyphenyl)-2-[(E)-3-(4-phenylmethoxyphenyl)prop-2-enoyl]oxypropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333286; BDBM50429234
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
(2R)-2-[[4-[4-[(3-Methyl-1-benzofuran-2-yl)methoxy]phenyl]phenyl]sulfonylamino]-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL372405
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
(Cycloheptylamino)carbonylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97614; SCHEMBL5886552; BDBM50146807
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-3-quinolin-8-ylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098999; BDBM50444719
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
(4S)-5-Amino-5-oxo-4-[[(2S)-2-[3-(4-phenylphenyl)propanoylamino]butanoyl]amino]pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3675544; SCHEMBL14233120; BDBM120192; US8691753, 40
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[54] | |||
| Compound Name |
(Cyclopropylamino)carbonylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL540952; BDBM50146815
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
(4S)-5-[[(2S)-1-Amino-3-carboxy-1-oxopropan-2-yl]amino]-5-oxo-4-[3-[4-(4-phenylthiophen-2-yl)phenyl]propanoylamino]pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL6868749; CHEMBL3675599; BDBM120252; US8691753, 101
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[54] | |||
| Compound Name |
(Hydroxysulfamoyl)dimethylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Hydroxysulfonamide 51; CHEMBL330950; SCHEMBL6791061; BDBM11370; N-(Dimethylsulfamoyl)hydroxylamine
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[34] | |||
| Compound Name |
N-[(2S,4S)-1-[4-[2-(4,6-Dimethylpyridin-3-yl)ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683461; BDBM50337739
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
(R)-2-(4''-((4-(Cyclohexanecarbonyl)phenoxy)methyl)biphenyl-4-ylsulfonamido)-3-methylbutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467891; SCHEMBL13978743; BDBM50258917
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-[(E)-3-(2,3-Dihydro-1-benzofuran-6-yl)prop-2-enoyl]oxy-3-(3,4-dimethoxyphenyl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333275; BDBM50429245
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
N-(Carboxymethyl)-N-(3-Phenylpropyl)glycyl-N-Methyl-L-Histidinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3235416; SCHEMBL12198648; BDBM50005641; Q27463133
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[55] | |||
| Compound Name |
(4S,5S)-4-Phenylsulfanyl-2-((E)-styryl)-5-vinyl-4,5-dihydro-oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL184020; BDBM50152649
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[38] | |||
| Compound Name |
(2R)-N-Hydroxy-4-methyl-2-[[methyl(phenyl)phosphoryl]amino]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL355754; (2R)-N-hydroxy-4-methyl-2-{[methyl(phenyl)phosphoryl]amino}pentanamide; SCHEMBL7403306; BDBM50291978; ZINC13782650; N-hydroxy-2(R)-[[(S)-methylphenylphosphinyl]amino]-4-methylpentanamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL585376; BDBM50299069
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazole-4-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL362099; BDBM50152637
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[38] | |||
| Compound Name |
(2R)-2-Amino-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL133199; BDBM50043598
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
N-({4'-[(4-Isobutyrylphenoxy)methyl]biphenyl-4-Yl}sulfonyl)-D-Valine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL511203; SCHEMBL13978734; BDBM50259007; Q27456853; N-({4''-[(4-isobutyrylphenoxy)methyl]biphenyl-4-yl}sulfonyl)-D-valine; (R)-2-(4''-((4-isobutyrylphenoxy)methyl)biphenyl-4-ylsulfonamido)-3-methylbutanoic acid; N-[(4'-{[4-(2-methylpropanoyl)phenoxy]methyl}biphenyl-4-yl)sulfonyl]-D-valine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-(3''-Bromo-biphenyl-4-sulfonylamino)-3-methyl-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43206; SCHEMBL7409278; BDBM50084299; (S)-2-(3''-bromo-biphenyl-4-sulfonylamino)-3-methyl-butyric acid; (2S)-2-[[4-(3-bromophenyl)phenyl]sulfonylamino]-3-methylbutanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[23] | |||
| Compound Name |
1,1,1-Trifluoro-N-hydroxymethanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Hydroxysulfonamide 47; CHEMBL331308; SCHEMBL8231627; BDBM11366; CTK1H6610; DTXSID10635307; Methanesulfonamide, 1,1,1-trifluoro-N-hydroxy-
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[34] | |||
| Compound Name |
(2R)-3-Methyl-2-[[4-[4-[(5-oxo-7,8-dihydro-6H-naphthalen-2-yl)oxymethyl]phenyl]phenyl]sulfonylamino]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466118; SCHEMBL8284164; BDBM50259009
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
N-(2-Methyl-4-amino-6-quinolyl)-3-(2-methoxyphenyl)propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098990; BDBM50444728
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
(2E)-2-(1H-Benzimidazol-2-yl)-3-(3-iodo-4-methoxyphenyl)prop-2-enenitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933865; BDBM50360392; STK288035; ZINC13943922; AKOS000417983; NCGC00330396-01; AB01325241-02
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[48] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-3-[2-(trifluoromethyl)phenyl]propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3099007; BDBM50444711
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-3-(2-methoxypyridin-3-yl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098973; BDBM50444760
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
1-(4-Amino-2-methylquinolin-6-yl)-3-(4-benzoylphenyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098982; BDBM50444751
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL318252; SCHEMBL3882021; BDBM50146472
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
Prop-2-enyl 3-(3,4-dimethoxyphenyl)-2-[(E)-3-[4-(trifluoromethyl)phenyl]prop-2-enoyl]oxypropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333282; BDBM50429238
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
2-(5-{(1R)-4-Cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-1,2,4-oxadiazol-3-yl)isonicotinic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL226853; SCHEMBL6599569; BDBM50216823
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
MMP Inhibitor, 3
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
US8691753, 97; SCHEMBL6868870; CHEMBL3675606; BDBM92443; Thiophene derivative, compound 36
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[54] | |||
| Compound Name |
N-Methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400314; BDBM50241371; 1-(2-(methylamino)-2-oxoethyl)-3-(5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)urea; N-Methyl-2-[3-[(5-thioxo-4,5-dihydro-1,3,4-thiadiazole)-2-yl]ureido]acetamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[25] | |||
| Compound Name |
3-(3,4-Dimethoxyphenyl)-2-[(E)-3-(4-methylphenyl)prop-2-enoyl]oxypropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333262; BDBM50429258
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
(S)-2-((R)-2-Acetylamino-3-mercapto-propionylamino)-3-phenyl-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55843; BDBM50287614
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[57] | |||
| Compound Name |
[2-(2-Cyclohexyl-1-phenethylcarbamoyl-ethylcarbamoyl)-5-p-tolyl-pentyl]-phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76869; BDBM50101522; [(S)-2-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethylcarbamoyl)-5-p-tolyl-pentyl]-phosphonic acid
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[30] | |||
| Compound Name |
(Cyclobutylamino)carbonylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL95763; Phosphonic acid, [(cyclobutylamino)carbonyl]- (9CI); BDBM50146800
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
N-[(2S,4S)-1-[4-[2-[2-Chloro-4-(trifluoromethyl)phenyl]ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683449; BDBM50337725
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
3-(3,4-Dimethoxyphenyl)-2-[(E)-3-(4-methoxyphenyl)prop-2-enoyl]oxypropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333270; BDBM50429249
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PD-503; CHEMBL409536; SCHEMBL5957461; PD503; BDBM50234334; ZINC29133346; DB08561; Q27097766
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-4-quinolin-8-ylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098994; BDBM50444724
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
3-(3,4-Dimethoxyphenyl)-2-[(E)-3-naphthalen-2-ylprop-2-enoyl]oxypropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333274; BDBM50429246
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
(1R,2S,5R)-2-[4-(4-Chlorophenyl)phenyl]sulfanyl-5-[(4-oxo-1,2,3-benzotriazin-3-yl)methyl]cyclopentane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126380; BDBM50131937
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
3-(1-Carbamoyl-2-cyclohexyl-ethylcarbamoyl)-6-phenyl-hexanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL307207; BDBM50101527; (R)-3-(((S)-1-amino-3-cyclohexyl-1-oxopropan-2-yl)carbamoyl)-6-phenylhexanoic acid; (R)-3-((S)-1-Carbamoyl-2-cyclohexyl-ethylcarbamoyl)-6-phenyl-hexanoic acid
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[30] | |||
| Compound Name |
Hydroxysulfonamide 48
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL124237; BDBM11367; 1,1,1-trichloro-N-hydroxymethanesulfonamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[34] | |||
| Compound Name |
Prop-2-enyl 2-[(E)-3-(4-chlorophenyl)prop-2-enoyl]oxy-3-(3,4-dimethoxyphenyl)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333283; BDBM50429237
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-3-quinolin-6-ylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3098995; BDBM50444723
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
(4S)-5-Amino-4-[[(2S)-4-carboxy-2-[3-(4-thiophen-2-ylphenyl)propanoylamino]butanoyl]amino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL6868823; CHEMBL3675581; BDBM120231; US8691753, 80
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[54] | |||
| Compound Name |
(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL389020; SCHEMBL5411951; BDBM50216802; (R)-6-cyclohexyl-N-hydroxy-3-(3-(methylsulfonamidomethyl)-1,2,4-oxadiazol-5-yl)hexanamide; (3R)-6-cyclohexyl-N-hydroxy-3-[3-(methanesulfonamidomethyl)-1,2,4-oxadiazol-5-yl]hexanamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
N-(4-Amino-2-methylquinolin-6-yl)-4-phenoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3099020; BDBM50444747
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2-(4-Oxo-4H-benzo[d][1,2,3]triazin-3-ylmethyl)-5-[4-(1H-[1,2,3]triazol-4-yl)-phenylsulfanyl]-cyclopentanecarboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339315; BDBM50131961
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
Benzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL402720; BDBM50227533
Click to Show/Hide
|
||||
| Activity |
IC50 = 101000 nM
|
[19] | |||
| Compound Name |
4-(4-Methoxyphenyl)-N-(2-morpholin-4-ylethyl)thiophene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL181682; Peakdale1_000543; SCHEMBL6450822; HMS519I15; BDBM50170202; N-(2-Morpholinoethyl)-4-(4-methoxyphenyl)thiophene-2-carboxamide; 4-(4-Methoxy-phenyl)-thiophene-2-carboxylic acid (2-morpholin-4-yl-ethyl)-amide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 101000 nM
|
[59] | |||
| Compound Name |
Cyclohexyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL442286; BDBM50227588
Click to Show/Hide
|
||||
| Activity |
IC50 = 102000 nM
|
[19] | |||
| Compound Name |
5-[4-[[3-Azido-5-(azidomethyl)benzoyl]amino]phenyl]-N-[7-(hydroxyamino)-7-oxoheptyl]-1,2-oxazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1914702; BDBM50356634
Click to Show/Hide
|
||||
| Activity |
IC50 = 108000 nM
|
[60] | |||
| Compound Name |
Thiophen-3-yl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399999; BDBM50227561
Click to Show/Hide
|
||||
| Activity |
IC50 = 108000 nM
|
[19] | |||
| Compound Name |
4-Methoxybenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399908; BDBM50227579
Click to Show/Hide
|
||||
| Activity |
IC50 = 108000 nM
|
[19] | |||
| Compound Name |
2-{Isopropoxy[(4-methoxyphenyl)sulfonyl]amino}-N-hydroxyacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL226439; BDBM50204371; N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonamido)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[61] | |||
| Compound Name |
2,5-Difluorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400449; BDBM50227576
Click to Show/Hide
|
||||
| Activity |
IC50 = 114000 nM
|
[19] | |||
| Compound Name |
2-[2-[(E)-(5-Oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenoxy]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927185; BDBM50359723
Click to Show/Hide
|
||||
| Activity |
IC50 = 114000 nM
|
[42] | |||
| Compound Name |
4-Phenoxybenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL250070; BDBM50227532
Click to Show/Hide
|
||||
| Activity |
IC50 = 114000 nM
|
[19] | |||
| Compound Name |
Naphthalen-1-yl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399504; BDBM50227555
Click to Show/Hide
|
||||
| Activity |
IC50 = 115000 nM
|
[19] | |||
| Compound Name |
Hexyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249859; BDBM50227581
Click to Show/Hide
|
||||
| Activity |
IC50 = 115000 nM
|
[19] | |||
| Compound Name |
3-Fluorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254611; BDBM50227528
Click to Show/Hide
|
||||
| Activity |
IC50 = 119000 nM
|
[19] | |||
| Compound Name |
6-Mercapto-pyridine-2-carboxylic acid biphenyl-4-ylmethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251425; BDBM50227590
Click to Show/Hide
|
||||
| Activity |
IC50 = 119000 nM
|
[19] | |||
| Compound Name |
N-Hydroxy-2-[4-(4-bromobenzyloxy)phenylsulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431029; BDBM50441228
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[37] | |||
| Compound Name |
Phenethyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL252522; BDBM50227599
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[19] | |||
| Compound Name |
4-Fluorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL250057; BDBM50227527
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[19] | |||
| Compound Name |
Dipotassium;2-[[2-[[(2S,3S)-2-[[ethoxy(oxido)phosphoryl]amino]-3-methylpentanoyl]amino]-3-(4-phenylmethoxyphenyl)propanoyl]amino]-3-phenylpropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1744415
Click to Show/Hide
|
||||
| Activity |
Ki = 120000 nM
|
[18] | |||
| Compound Name |
Isopropyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL404205; BDBM50227591
Click to Show/Hide
|
||||
| Activity |
IC50 = 121000 nM
|
[19] | |||
| Compound Name |
2,4,5-Trifluorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL250059; BDBM50227592
Click to Show/Hide
|
||||
| Activity |
IC50 = 124000 nM
|
[19] | |||
| Compound Name |
4-Chlorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251081; BDBM50227556
Click to Show/Hide
|
||||
| Activity |
IC50 = 126000 nM
|
[19] | |||
| Compound Name |
4-[4-(Thiirane-2-ylmethylsulfonyl)phenoxy]phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2063274; SCHEMBL10238452; BDBM50388914
Click to Show/Hide
|
||||
| Activity |
Ki = 128000 nM
|
[62] | |||
| Compound Name |
Benzo[d][1,3]dioxol-5-ylmethyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253189; BDBM50227540
Click to Show/Hide
|
||||
| Activity |
IC50 = 128000 nM
|
[19] | |||
| Compound Name |
Dipotassium;2-[[(2S)-2-[[(2S,3S)-2-[[ethoxy(oxido)phosphoryl]amino]-3-methylpentanoyl]amino]propanoyl]amino]acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2369488; BDBM50367930
Click to Show/Hide
|
||||
| Activity |
Ki = 130000 nM
|
[18] | |||
| Compound Name |
3-(Trifluoromethyl)benzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254405; BDBM50227535
Click to Show/Hide
|
||||
| Activity |
IC50 = 134000 nM
|
[19] | |||
| Compound Name |
Cyclobutyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL252327; BDBM50227539
Click to Show/Hide
|
||||
| Activity |
IC50 = 135000 nM
|
[19] | |||
| Compound Name |
4-Phenoxybutyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254610; BDBM50227602
Click to Show/Hide
|
||||
| Activity |
IC50 = 138000 nM
|
[19] | |||
| Compound Name |
4-(4-(Thiiran-2-ylmethylsulfonyl)phenoxy)phenyl methanesulfonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1651842; SCHEMBL10238468; BDBM50335495
Click to Show/Hide
|
||||
| Activity |
Ki = 140000 nM
|
[63] | |||
| Compound Name |
Dipotassium;2-[[(2S)-2-[[(2S)-2-[[ethoxy(oxido)phosphoryl]amino]-4-methylpentanoyl]amino]propanoyl]amino]acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2369489; BDBM50367935
Click to Show/Hide
|
||||
| Activity |
Ki = 140000 nM
|
[18] | |||
| Compound Name |
1-Cinnamyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249249; BDBM50227597
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
3-((2-Phenethyl-2H-tetrazol-5-yl)methyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251465; BDBM50227530
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
Naphthalen-1-yl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251423; BDBM50227543
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
4-(4,5-Dihydrooxazol-2-yl)-1-phenethyl-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400851; BDBM50227577
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
6-Mercapto-pyridine-2-carboxylic acid 4-methyl-benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254404; BDBM50227582
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
1-Cyclohexenyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249860; BDBM50227560
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
4-(4,5-Dihydrooxazol-2-yl)-1-(3-phenylpropyl)-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249863; BDBM50227536
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
6-Mercapto-pyridine-2-carboxylic acid 3-methyl-benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254403; BDBM50227572
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
2-Bromobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399997; BDBM50227598
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
3-((2-Benzyl-2H-tetrazol-5-yl)methyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400357; BDBM50227573
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
4-(4,5-Dihydrooxazol-2-yl)-1-hexyl-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249861; BDBM50227550
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
(E)-3-((2-Cinnamyl-2H-tetrazol-5-yl)methyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL428762; BDBM50227546
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
4-(4,5-Dihydrooxazol-2-yl)-1-heptyl-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400850; BDBM50227570
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
5-(3-Pyridylmethyl)-1H-tetrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399998; 3-(2H-tetrazol-5-ylmethyl)pyridine; BDBM50227558; AKOS000262059; 3-((2H-tetrazol-5-yl)methyl)pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
1-Benzyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249862; BDBM50227566; J3.517.457E; 1-Benzyl-4-(2-oxazoline-2-yl)-1H-1,2,3-triazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
4-(Trifluoromethyl)benzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL398662; BDBM50227544
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
3-((2-(3-Phenylpropyl)-2H-tetrazol-5-yl)methyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400358; BDBM50227594
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[19] | |||
| Compound Name |
N-Hydroxy-2-[4-(3,5-difluorobenzyloxy)phenylsulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431020; BDBM50441219
Click to Show/Hide
|
||||
| Activity |
IC50 = 181000 nM
|
[37] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 106 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Benzyl N-[(4R)-4-[[4-(4-cyano-2-methylphenyl)piperazin-1-yl]sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770688
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[64] | |||
| Compound Name |
N-Hydroxy-2-[4-(3,5-dibromobenzyloxy)phenylsulfonyl(methyl)amino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431022; BDBM50441218
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[37] | |||
| Compound Name |
3-Hydroxy-N-methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251901; BDBM50241377; (S)-3-Hydroxy-N-methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[25] | |||
| Compound Name |
(R)-N-Methyl-3-phenyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL398702; SCHEMBL6953380; BDBM50241373; (2R)-N-methyl-3-phenyl-2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)carbamoylamino]propanamide
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[25] | |||
| Compound Name |
Thioacetic acid S-[(4S,5S)-2-(4-bromo-phenyl)-5-vinyl-4,5-dihydro-oxazol-4-yl] ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL363675; BDBM50152647
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[38] | |||
| Compound Name |
(S)-3-Phenyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39553; SCHEMBL6953038; BDBM50076343; ZINC13796963; (2S)-3-phenyl-2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)carbamoylamino]propanamide; (S)-alpha-[3-[(5-Thioxo-4,5-dihydro-1,3,4-thiadiazol)-2-yl]ureido]benzenepropanamide
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[25] | |||
| Compound Name |
N-Hydroxy-2-[4-(4-methanesulfinyl-phenoxy)-benzenesulfonyl]-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL576762; BDBM50299066
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
N-Hydroxy-2-[4-[3-bromo-5-(p-anisyl)benzyloxy]phenylsulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431024; BDBM50441217
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[37] | |||
| Compound Name |
(4S,5S)-2-(4-Bromo-phenyl)-5-vinyl-4,5-dihydro-oxazole-4-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL184492; BDBM50152651
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[38] | |||
| Compound Name |
(S)-1-(4-Methyl-1-(methylamino)-1-oxopentan-2-yl)-3-(5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249848; BDBM50241375; (S)-4-Methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-pentanoic acid methylamide
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[25] | |||
| Compound Name |
N-[(1S,2S)-2-Hydroxycyclopentyl]-4-phenoxybenzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380397; BDBM50433870
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[14] | |||
| Compound Name |
N-[[(4,5-Dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)amino]carbonyl]-L-phenylalanine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288866; SCHEMBL2679911; ZINC2583786; BDBM50076333; (S)-3-Phenyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionic acid
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[25] | |||
| Compound Name |
4-Phenoxy-N-[(1S,2S)-2-sulfanylcyclopentyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380398; BDBM50433869
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[14] | |||
| Compound Name |
(S)-N-Cyclohexylmethyl-3-phenyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL38263; mmp-3 inhibitor iv; SCHEMBL5443538; CTK8G1149; ZINC3874283; BDBM50076348
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[25] | |||
| Compound Name |
[4-[4-(Thiiran-2-ylmethylsulfonyl)phenoxy]phenyl]methanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2063273; SCHEMBL10187460; BDBM50388912
Click to Show/Hide
|
||||
| Activity |
Ki = 205000 nM
|
[62] | |||
| Compound Name |
2-[(4-Phenoxyphenyl)sulfonylmethyl]thiirane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SB-3CT; 2-((4-phenoxyphenylsulfonyl)methyl)thiirane; SB3CT; SB 3CT; CHEMBL483857; 2-(((4-Phenoxyphenyl)sulfonyl)methyl)thiirane; Thiirane, 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-; 2-[(4-PHENOXYBENZENESULFONYL)METHYL]THIIRANE; MMP-2/MMP-9 Inhibitor IV; 2-[[(4-Phenoxyphenyl)sulfonyl]methyl]thiirane; 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-Thiirane; Thiirane, 1; (4-phenoxyphenylsulfonyl)methylthiirane; MLS006010722; Thiirane (deuterium), 1-d2; GTPL9509; SCHEMBL2684163; CTK8F0499; KS-00001CWI; AOB6468; DTXSID70432359; EX-A687; C15H14O3S2; HMS3653B03; BCP10428; 2705AH; BDBM50264809; MFCD09836266; s7430; AKOS026750307; CCG-267539; CS-3445; inhibitor 1 (Brown et al., 2000); SB-3CT, >=98% (HPLC), powder; NCGC00346932-01; 2-(4-phenoxyphenylsulfonylmethyl)thiirane; AC-32656; AK270339; AS-67674; HY-12354; SMR004701685; DS-015900; FT-0700278; SW219838-1; 2-[[4-(phenoxy)phenyl]sulfonylmethyl]thiirane; J-017452; Q27165480
Click to Show/Hide
|
||||
| Activity |
Ki = 206000 nM
|
[63] | |||
| Compound Name |
(S)-N,N-Dimethyl-3-phenyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40034; SCHEMBL6951421; BDBM50076370; ZINC13796965; (2S)-N,N-dimethyl-3-phenyl-2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)carbamoylamino]propanamide; (S)-N,N-Dimethyl-alpha-[3-[(5-thioxo-4,5-dihydro-1,3,4-thiadiazol)-2-yl]ureido]benzenepropanamide
Click to Show/Hide
|
||||
| Activity |
Ki = 226000 nM
|
[25] | |||
| Compound Name |
Dipotassium;(2S)-2-[[2-[[(2S)-2-[[(2S,3S)-2-[[ethoxy(oxido)phosphoryl]amino]-3-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2369491; BDBM50367925
Click to Show/Hide
|
||||
| Activity |
Ki = 240000 nM
|
[18] | |||
| Compound Name |
Chembl4210206
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL315491; BDBM50455767; N-hydroxy-2-[2-[4-(4-methoxyphenyl)phenyl]sulfanylphenyl]acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[65] | |||
| Compound Name |
2-Amino-3-(4-methoxyphenylsulfonyl)propanehydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90057; BDBM50105432; 2-Amino-N-hydroxy-3-(4-methoxy-benzenesulfonyl)-propionamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[40] | |||
| Compound Name |
(S)-N-Hydroxy-2-[methyl-(2-pyridin-4-yl-acetyl)-amino]-3-(4-phenoxy-benzenesulfonyl)-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327202; BDBM50105430
Click to Show/Hide
|
||||
| Activity |
IC50 = 258000 nM
|
[40] | |||
| Compound Name |
Chembl4203044
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455775
Click to Show/Hide
|
||||
| Activity |
IC50 = 260000 nM
|
[65] | |||
| Compound Name |
(4S)-5-[[(2S)-5-[[Amino(nitramido)methylidene]amino]-1-(carboxymethylamino)-1-oxopentan-2-yl]amino]-4-[[2-[[(2S)-2-[[(2S,3S)-2-[[ethoxy(hydroxy)phosphoryl]amino]-3-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372451; BDBM50013121
Click to Show/Hide
|
||||
| Activity |
Ki = 270000 nM
|
[18] | |||
| Compound Name |
N-[(Hydroxyamino)carbonyl]-L-leucyl-Lphenylalanine methylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL501715; BDBM50272134
Click to Show/Hide
|
||||
| Activity |
IC50 = 270000 nM
|
[66] | |||
| Compound Name |
2-(Acetylamino)-3-(4-methoxyphenylsulfonyl)propanehydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329686; SCHEMBL7181926; BDBM50105444; 2-acetamido-N-hydroxy-3-(4-methoxyphenyl)sulfonylpropanamide; 2-Acetylamino-N-hydroxy-3-(4-methoxy-benzenesulfonyl)-propionamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[40] | |||
| Compound Name |
[(4S,5S)-2-(4-Chloro-phenyl)-5-vinyl-4,5-dihydro-oxazol-4-yl]-methanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL424792; BDBM50152640
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[38] | |||
| Compound Name |
N-[(Hydroxyamino)carbonyl]-D-leucyl-Lphenylalanine methylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL452082; BDBM50245247
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[66] | |||
| Compound Name |
D-Leucyl-L-phenylalanine methylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL510082; BDBM50245251
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[66] | |||
| Compound Name |
{(4S,5S)-2-[2-(4-Bromo-phenyl)-vinyl]-5-vinyl-4,5-dihydro-oxazol-4-yl}-methanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL186648; BDBM50152650
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[38] | |||
| Compound Name |
3,2-Diguanidinoneamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3,2'-diguanidinoneamine; CHEMBL215074; BDBM12005; Neamine guanidinylated deriv. 21
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[67] | |||
| Compound Name |
Neamine guanidinylated deriv. 29
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215715; BDBM12012; 1,3,2,6-Tetraguanidino-5,6,3,4-tetramethoxylneamine
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[67] | |||
| Compound Name |
Neamine guanidinylated deriv. 4
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215269; 1,3,2,6-Tetraguanidinoneamine; BDBM11997; 1,3,2',6'-tetraguanidinoneamine
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[67] | |||
| Compound Name |
Z-L-Leu-L-Phe-OMe
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL452584; SCHEMBL7326037; BDBM50245249; N-benzyloxycarbonyl-L-leucyl-L-phenylalanine methyl ester; N-(Benzyloxycarbonyl)-L-leucyl-L-phenylalanine methyl ester; methyl (2S)-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-3-phenylpropanoate
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[66] | |||
| Compound Name |
1,3,2-Triguanidinoneamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,3,2'-triguanidinoneamine; CHEMBL438810; BDBM12008; Neamine guanidinylated deriv. 23
Click to Show/Hide
|
||||
| Activity |
Ki > 300000 nM
|
[67] | |||
| Compound Name |
(4s)-3-{[4-(4-Cyano-2-Methylphenyl)piperazin-1-Yl]sulfonyl}-N-Hydroxy-1,3-Thiazolidine-4-Carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770935; Q27462716
Click to Show/Hide
|
||||
| Activity |
IC50 = 346000 nM
|
[64] | |||
| Compound Name |
N-[(S)-1-Hydroxycarbamoyl-2-(4-phenoxy-benzenesulfonyl)-ethyl]-2,6-dimethoxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL316293; BDBM50105436
Click to Show/Hide
|
||||
| Activity |
IC50 = 350000 nM
|
[40] | |||
| Compound Name |
(2Z,NE)-N-benzylidene-4-(3,4-dimethoxyphenyl)-2-(phenylimino)thiazol-3(2H)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927187; BDBM50359725; STL264510; AKOS002238584; ST50113618; F0807-0342; (2Z)-4-(3,4-dimethoxyphenyl)-2-(phenylimino)-N-[(E)-phenylmethylidene]-1,3-thiazol-3(2H)-amine; 4-[3-((1E)-2-phenyl-1-azavinyl)-2-(phenylazamethylene)(1,3-thiazolin-4-yl)]-1, 2-dimethoxybenzene
Click to Show/Hide
|
||||
| Activity |
IC50 = 360000 nM
|
[42] | |||
| Compound Name |
N-[1-(2,6-Dioxo-4,4-dimethylpiperidinomethyl)-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288701; SCHEMBL7448709; BDBM50100916
Click to Show/Hide
|
||||
| Activity |
IC50 = 360000 nM
|
[11] | |||
| Compound Name |
Benzyl N-[(4R)-4-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431027; BDBM50441213
Click to Show/Hide
|
||||
| Activity |
IC50 = 370000 nM
|
[64] | |||
| Compound Name |
(2R)-N-Hydroxy-2-[4-(3,5-dibromobenzyloxy)phenylsulfonylamino]-4-(benzyloxycarbonylamino)butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431026; BDBM50441214
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[37] | |||
| Compound Name |
3-(4-(2-Oxo-2H-chromen-3-yl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927183; ZINC2957866; BDBM50359721; AKOS024602290; MCULE-4659831116; F0920-6501
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[42] | |||
| Compound Name |
2-(Tosylamino)-3-(4-phenoxyphenylsulfonyl)propanehydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90764; BDBM50105437; N-Hydroxy-3-(4-phenoxy-benzenesulfonyl)-2-(toluene-4-sulfonylamino)-propionamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[40] | |||
| Compound Name |
(2R)-2-[[4-[4-[(5-Bromo-4-methoxy-3-methyl-1-benzofuran-2-yl)methoxy]phenyl]phenyl]sulfonylamino]-3-methylbutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL497772; SCHEMBL8287194; BDBM50265076
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[2] | |||
| Compound Name |
Thioacetic acid S-((4S,5S)-2-biphenyl-4-yl-5-vinyl-4,5-dihydro-oxazol-4-yl) ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL363953; BDBM50152633
Click to Show/Hide
|
||||
| Activity |
Ki > 400000 nM
|
[38] | |||
| Compound Name |
(4S)-5-[[(2S)-1-(Carboxymethylamino)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-[[2-[[(2S)-2-[[(2S,3S)-2-[[ethoxy(hydroxy)phosphoryl]amino]-3-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1160644
Click to Show/Hide
|
||||
| Activity |
Ki = 403000 nM
|
[18] | |||
| Compound Name |
(S)-N-Hydroxy-2-methylamino-3-(4-phenoxy-benzenesulfonyl)-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL93993; BDBM50105445
Click to Show/Hide
|
||||
| Activity |
IC50 = 440000 nM
|
[40] | |||
| Compound Name |
2-[[(2S)-2-[[(2S)-5-Amino-2-[[2-[[(2S)-2-[[(2S,3S)-2-[[ethoxy(hydroxy)phosphoryl]amino]-3-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1160626
Click to Show/Hide
|
||||
| Activity |
Ki = 460000 nM
|
[18] | |||
| Compound Name |
(S)-2-(Benzyl-methyl-amino)-N-hydroxy-3-(4-phenoxy-benzenesulfonyl)-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL93725; BDBM50105425
Click to Show/Hide
|
||||
| Activity |
IC50 = 475000 nM
|
[40] | |||
| Compound Name |
Chembl4171886
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50278388
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[68] | |||
| Compound Name |
((4S,5S)-2-Benzyl-5-vinyl-4,5-dihydro-oxazol-4-yl)-methanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL186538; BDBM50152636
Click to Show/Hide
|
||||
| Activity |
Ki > 500000 nM
|
[38] | |||
| Compound Name |
(2R)-5-[(Aminocarbonyl)amino]-2-[[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonyl]amino]-N-hydroxy-pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
JG26; CHEMBL2431028; BDBM50441212
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[37] | |||
| Compound Name |
Chembl4160618
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50278364
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[68] | |||
| Compound Name |
N-Hydroxy-2-[[4-[[3-(trifluoromethoxy)phenyl]methoxy]phenyl]sulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431017; BDBM50441222
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[37] | |||
| Compound Name |
N-Hydroxy-2-[[4-[(4-phenylphenyl)methoxy]phenyl]sulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431032; BDBM50441225
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[37] | |||
| Compound Name |
Chembl4175156
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50278390
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[68] | |||
| Compound Name |
Chembl4167291
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50278365
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[68] | |||
| Compound Name |
N-Hydroxy-2-[4-(3,5-dibromobenzyloxy)phenylsulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431021; BDBM50441215
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[37] | |||
| Compound Name |
N-Hydroxy-2-[4-[3-bromo-5-(3-pyridyl)benzyloxy]phenylsulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431025; BDBM50441216
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[37] | |||
| Compound Name |
Chembl4162521
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50278366
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[68] | |||
| Compound Name |
Chembl4163839
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50278363
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[68] | |||
| Compound Name |
N-Hydroxy-2-[4-(3-bromobenzyloxy)phenylsulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431015; BDBM50441224
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[37] | |||
| Compound Name |
Chembl4164016
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50278389
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[68] | |||
| Compound Name |
Chembl4170455
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50278367
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[68] | |||
| Compound Name |
[(S)-1-Hydroxycarbamoyl-2-(4-phenoxy-benzenesulfonyl)-ethyl]-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329104; BDBM50105433
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[40] | |||
| Compound Name |
4-[4-[2-(Diethylamino)ethoxy]phenyl]-N-hydroxy-2-[(7-methyl-2-oxochromen-3-yl)methyl]butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630091; BDBM50332480
Click to Show/Hide
|
||||
| Activity |
IC50 = 557000 nM
|
[69] | |||
| Compound Name |
2-(Tosylamino)-3-[4-(phenylthio)phenylsulfonyl]propanehydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94185; BDBM50105426; N-Hydroxy-3-(4-phenylsulfanyl-benzenesulfonyl)-2-(toluene-4-sulfonylamino)-propionamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 600000 nM
|
[40] | |||
| Compound Name |
N-Hydroxy-2-[4-(8-quinolylmethoxy)phenylsulfonylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431019; BDBM50441220
Click to Show/Hide
|
||||
| Activity |
IC50 = 620000 nM
|
[37] | |||
| Compound Name |
2-(Acetylamino)-3-(4-phenoxyphenylsulfonyl)propanehydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91668; BDBM50105427; 2-Acetylamino-N-hydroxy-3-(4-phenoxy-benzenesulfonyl)-propionamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 770000 nM
|
[40] | |||
| Compound Name |
(E)-2-(5-((5-(4-Methoxyphenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927186; ZINC2698193; BDBM50359724; STK711873; AKOS002386597; ST50326453; AB00674549-01; F1542-0089
Click to Show/Hide
|
||||
| Activity |
IC50 = 860000 nM
|
[42] | |||
| Compound Name |
N-[(S)-1-Hydroxycarbamoyl-2-(4-phenoxy-benzenesulfonyl)-ethyl]-isonicotinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329599; BDBM50105443
Click to Show/Hide
|
||||
| Activity |
IC50 = 900000 nM
|
[40] | |||
| Compound Name |
(2S)-2-[[Ethoxy(hydroxy)phosphoryl]amino]-4-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1160639
Click to Show/Hide
|
||||
| Activity |
Ki = 950000 nM
|
[18] | |||
| Compound Name |
(2S,3S)-2-[[Ethoxy(hydroxy)phosphoryl]amino]-3-methylpentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1160645
Click to Show/Hide
|
||||
| Activity |
Ki = 990000 nM
|
[18] | |||
| Compound Name |
2-(Benzyloxycarbonylamino)-3-(4-phenoxyphenylsulfonyl)propanehydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL419875; SCHEMBL7308069; BDBM50105440; [1-Hydroxycarbamoyl-2-(4-phenoxy-benzenesulfonyl)-ethyl]-carbamic acid benzyl ester; benzyl N-[1-(hydroxyamino)-1-oxo-3-(4-phenoxyphenyl)sulfonylpropan-2-yl]carbamate
Click to Show/Hide
|
||||
| Activity |
IC50 = 1400000 nM
|
[40] | |||
| Compound Name |
2-(Tert-Butoxycarbonylamino)-3-(4-methoxyphenylsulfonyl)propanehydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327901; SCHEMBL7868827; BDBM50105446; [1-Hydroxycarbamoyl-2-(4-methoxy-benzenesulfonyl)-ethyl]-carbamic acid tert-butyl ester; tert-butyl N-[1-(hydroxyamino)-3-(4-methoxyphenyl)sulfonyl-1-oxopropan-2-yl]carbamate
Click to Show/Hide
|
||||
| Activity |
IC50 = 1500000 nM
|
[40] | |||
| Compound Name |
[(S)-1-Hydroxycarbamoyl-2-(4-phenoxy-benzenesulfonyl)-ethyl]-methyl-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328792; BDBM50105438
Click to Show/Hide
|
||||
| Activity |
IC50 = 1600000 nM
|
[40] | |||
| Compound Name |
(2S)-2-[[(2S)-5-Amino-2-[[2-[[(2S)-2-[[(2S,3S)-2-[[ethoxy(hydroxy)phosphoryl]amino]-3-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-5-oxopentanoyl]amino]-5-[[amino(nitramido)methylidene]amino]pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL609445
Click to Show/Hide
|
||||
| Activity |
Ki = 1900000 nM
|
[18] | |||
| Compound Name |
N-[1-(4'-Cyano-4-biphenylyloxymethyl)-2-(2,5-dioxo-4,4-dimethylimidazolidine-1-yl)ethyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41102; SCHEMBL7501269; BDBM50100918
Click to Show/Hide
|
||||
| Activity |
IC50 = 2100000 nM
|
[11] | |||
| Compound Name |
N-[1-(4'-Cyano-4-biphenylyloxymethyl)-2-(2,5-dioxo-3,4,4-trimethylimidazolidine-1-yl)ethyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288067; SCHEMBL7505333; BDBM50100902
Click to Show/Hide
|
||||
| Activity |
IC50 = 2300000 nM
|
[11] | |||
| Compound Name |
N-[1-(4'-Cyano-4-biphenylyloxymethyl)-2-(2,5-dioxo-3-ethyl-4,4-dimethylimidazolidine-1-yl)ethyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288592; SCHEMBL7451091; BDBM50100917
Click to Show/Hide
|
||||
| Activity |
IC50 = 2400000 nM
|
[11] | |||
| Compound Name |
3-(4''-Cyanobiphenyl-4-yloxy)-N-hydroxy-2-methylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41923; BDBM50100899; 3-(4''-Cyano-biphenyl-4-yloxy)-N-hydroxy-2-methyl-propionamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 2500000 nM
|
[11] | |||
| Compound Name |
N-[1-(Phenylthiomethyl)-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39358; SCHEMBL7498355; BDBM50100913; N-[1-(4''-Cyano-biphenyl-4-yloxymethyl)-2-phenylsulfanyl-ethyl]-N-hydroxy-formamide; N-[1-[4-(4-cyanophenyl)phenoxy]-3-phenylsulfanylpropan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 4100000 nM
|
[11] | |||
| Compound Name |
N-[1-[4-(4-Cyanophenyl)phenoxy]-3-(3-methyl-6-oxopyridazin-1-yl)propan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL415872; SCHEMBL7504330; BDBM50100911
Click to Show/Hide
|
||||
| Activity |
IC50 = 4200000 nM
|
[11] | |||
| Compound Name |
(2R)-2-[(3R)-3-Amino-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]-2-oxopyrrolidin-1-yl]-N-hydroxy-3-methylbutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630098; BDBM50332481
Click to Show/Hide
|
||||
| Activity |
IC50 = 4926000 nM
|
[69] | |||
| Compound Name |
[(S)-1-Hydroxycarbamoyl-2-(4-phenylsulfanyl-benzenesulfonyl)-ethyl]-carbamic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90604; BDBM50105435
Click to Show/Hide
|
||||
| Activity |
IC50 = 8000000 nM
|
[40] | |||
| Compound Name |
(1R,2S)-1-({3-Fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}methyl)-2-N-hydroxycyclopropane-1,2-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461220; SCHEMBL13648029; BDBM26524; hydroxamate-cyclopropyl compound, 1
Click to Show/Hide
|
||||
| Activity |
Ki > 10000000 nM
|
[70] | |||
| Compound Name |
Hydroxamate deriv., 78
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BMCL1954 Compound 3; CHEMBL269834; SCHEMBL8357412; BDBM23487
Click to Show/Hide
|
||||
| Activity |
Ki > 10000000 nM
|
[70] | |||
| Compound Name |
(1R,2S)-Ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495555; SCHEMBL13648000; BDBM50292683
Click to Show/Hide
|
||||
| Activity |
Ki > 10000000 nM
|
[70] | |||
| Compound Name |
(1R,2S)-Ethyl 2-(hydroxycarbamoyl)-1-(4-((2-methylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL497810; SCHEMBL13648009; BDBM50292684
Click to Show/Hide
|
||||
| Activity |
Ki > 10000000 nM
|
[70] | |||
| Compound Name |
N-[1-(Phenoxymethyl)-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41485; SCHEMBL7504451; BDBM50100907; N-[1-[4-(4-cyanophenyl)phenoxy]-3-phenoxypropan-2-yl]-N-hydroxyformamide; N-[2-(4''-Cyano-biphenyl-4-yloxy)-1-phenoxymethyl-ethyl]-N-hydroxy-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[11] | |||
| Compound Name |
N-[1-(4'-Cyano-4-biphenylyloxymethyl)-3-methylbutyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42862; SCHEMBL7509014; BDBM50100914; N-[1-[4-(4-cyanophenyl)phenoxy]-4-methylpentan-2-yl]-N-hydroxyformamide; N-[1-(4''-Cyano-biphenyl-4-yloxymethyl)-3-methyl-butyl]-N-hydroxy-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[11] | |||
| Compound Name |
(1S,2R)-2-Cyano-N-hydroxy-2-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL497769; BDBM50292680
Click to Show/Hide
|
||||
| Activity |
Ki > 10000000 nM
|
[70] | |||
| Compound Name |
2-(Acetylamino)-3-[4-(phenylthio)phenylsulfonyl]propanehydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL93074; SCHEMBL7186097; BDBM50105424; 2-acetamido-N-hydroxy-3-(4-phenylsulfanylphenyl)sulfonylpropanamide; 2-(acetylamino)-n-hydroxy-3-[[4-(phenylthio)phenyl]sulfonyl]propanamide; 2-Acetylamino-N-hydroxy-3-(4-phenylsulfanyl-benzenesulfonyl)-propionamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[40] | |||
| Compound Name |
N-[1-(Phthalimidylmethyl)-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL38717; SCHEMBL7497786; BDBM50100900; N-[1-[4-(4-cyanophenyl)phenoxy]-3-(1,3-dioxoisoindol-2-yl)propan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[11] | |||
| Compound Name |
N-[1-(4'-Cyano-4-biphenylyloxymethyl)-3-(2,5-dioxo-3,4,4-trimethylimidazolidine-1-yl)propyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL290457; SCHEMBL7500945; BDBM50100909
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[11] | |||
| Compound Name |
N-[2-[4-(4-Cyanophenyl)phenoxy]-1-(4-fluorophenyl)ethyl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39035; SCHEMBL7505043; BDBM50100906; N-[2-(4''-Cyano-biphenyl-4-yloxy)-1-(4-fluoro-phenyl)-ethyl]-N-hydroxy-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[11] | |||
| Compound Name |
{[1-Hydroxycarbamoyl-2-(4-phenylsulfanyl-benzenesulfonyl)-ethylcarbamoyl]-methyl}-carbamic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328121; BDBM50105429; 2-[N-(Benzyloxycarbonyl)glycylamino]-3-[4-(phenylthio)phenylsulfonyl]propanehydroximic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[40] | |||
| Compound Name |
(1R,2S)-1-(3-Fluoro-4-((2-phenylquinolin-4-yl)methoxy)benzyl)-N2-hydroxy-N1,N1-dimethylcyclopropane-1,2-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL496309; SCHEMBL13648378; BDBM50292682
Click to Show/Hide
|
||||
| Activity |
Ki > 10000000 nM
|
[70] | |||
| Compound Name |
N-[1-[4-(4-Cyanophenyl)phenoxy]propan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41067; SCHEMBL7453489; BDBM50100919; N-[1-Methyl-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid; N-[2-(4''-Cyano-biphenyl-4-yloxy)-1-methyl-ethyl]-N-hydroxy-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[11] | |||
| Compound Name |
(1S,2R)-N-Hydroxy-2-((S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl)-2-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL506057; SCHEMBL13648344; BDBM50292681
Click to Show/Hide
|
||||
| Activity |
Ki > 10000000 nM
|
[70] | |||
| Compound Name |
N-[1-(Succinimidylmethyl)-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL434204; SCHEMBL7443814; BDBM50100915; N-[1-(4''-Cyano-biphenyl-4-yloxymethyl)-2-(2,5-dioxo-pyrrolidin-1-yl)-ethyl]-N-hydroxy-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[11] | |||
| Compound Name |
2-Amino-3-[4-(phenylthio)phenylsulfonyl]propanehydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL316122; BDBM50105431; 2-Amino-N-hydroxy-3-(4-phenylsulfanyl-benzenesulfonyl)-propionamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[40] | |||
| Compound Name |
[(S)-1-Hydroxycarbamoyl-2-(4-phenylsulfanyl-benzenesulfonyl)-ethyl]-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90456; BDBM50105441
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[40] | |||
| Compound Name |
2-(Benzyloxycarbonylamino)-3-[4-(phenylthio)phenylsulfonyl]propanehydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91608; BDBM50105428; [1-Hydroxycarbamoyl-2-(4-phenylsulfanyl-benzenesulfonyl)-ethyl]-carbamic acid benzyl ester; benzyl N-[1-(hydroxyamino)-1-oxo-3-(4-phenylsulfanylphenyl)sulfonylpropan-2-yl]carbamate
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[40] | |||
| Compound Name |
(S)-2-Acetylamino-N-hydroxy-3-(4-phenylsulfanyl-benzenesulfonyl)-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL93058; BDBM50105434
Click to Show/Hide
|
||||
| Activity |
IC50 = 10000000 nM
|
[40] | |||
| Compound Name |
N-[1-[4-(4-Cyanophenyl)phenoxy]-3-(4-fluorophenyl)propan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289108; SCHEMBL7504912; BDBM50100901; N-[1-(4''-Cyano-biphenyl-4-yloxymethyl)-2-(4-fluoro-phenyl)-ethyl]-N-hydroxy-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 14000000 nM
|
[11] | |||
| Compound Name |
N-[1-(4'-Cyano-4-biphenylyloxymethyl)-3-(2,5-dioxo-4,4-dimethylimidazolidine-1-yl)propyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288510; SCHEMBL7506792; BDBM50100905
Click to Show/Hide
|
||||
| Activity |
IC50 = 14000000 nM
|
[11] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | US patent application no. 9206139B2, Aggrecanase inhibitors | ||||
| REF 2 | Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. Bioorg Med Chem. 2008 Oct 1;16(19):8781-94. | ||||
| REF 3 | Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhib... J Med Chem. 2009 Oct 22;52(20):6347-61. | ||||
| REF 4 | The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5760-3. | ||||
| REF 5 | Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment ... Bioorg Med Chem Lett. 2010 Jan 15;20(2):576-80. | ||||
| REF 6 | Phenoxyphenyl sulfone N-formylhydroxylamines (retrohydroxamates) as potent, selective, orally bioavailable matrix metalloproteinase inhibitors. J Med Chem. 2002 Jan 3;45(1):219-32. | ||||
| REF 7 | Synthesis and activity of tryptophan sulfonamide derivatives as novel non-hydroxamate TNF-alpha converting enzyme (TACE) inhibitors. Bioorg Med Chem. 2009 Jun 1;17(11):3857-65. | ||||
| REF 8 | Design and synthesis of a series of (2R)-N(4)-hydroxy-2-(3-hydroxybenzyl)-N(1)- [(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivati... J Med Chem. 2001 Oct 11;44(21):3347-50. | ||||
| REF 9 | Small molecule inhibitors of anthrax lethal factor toxin. Bioorg Med Chem. 2014 Jan 1;22(1):419-34. | ||||
| REF 10 | Diaryl ether derivatives as anticancer agents - a review. Medchemcomm. 2012;3:1356-72. | ||||
| REF 11 | Biaryl ether retrohydroxamates as potent, long-lived, orally bioavailable MMP inhibitors. Bioorg Med Chem Lett. 2001 Jun 18;11(12):1553-6. | ||||
| REF 12 | Amide surrogates of matrix metalloproteinase inhibitors: Urea and sulfonamide mimics. Bioorg Med Chem Lett. 1997 Sep 23;7(18):2331-6. | ||||
| REF 13 | Synthesis of hydroxypyrone- and hydroxythiopyrone-based matrix metalloproteinase inhibitors: developing a structure-activity relationship. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1970-6. | ||||
| REF 14 | Matrix metalloproteinase inhibitors based on the 3-mercaptopyrrolidine core. J Med Chem. 2013 Jun 13;56(11):4357-73. | ||||
| REF 15 | Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2242-6. | ||||
| REF 16 | The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1189-93 | ||||
| REF 17 | Stereospecific synthesis of 5-substituted 2-bisarylthiocyclopentane carboxylic acids as specific matrix metalloproteinase inhibitors. J Med Chem. 2003 Aug 28;46(18):3840-52. | ||||
| REF 18 | Phosphoramidate peptide inhibitors of human skin fibroblast collagenase. J Med Chem. 1990 Jan;33(1):263-73. | ||||
| REF 19 | Synthesis and evaluation of novel heterocyclic MMP inhibitors. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6864-70. | ||||
| REF 20 | Inhibition of Matrix Metalloproteinases: An examination of the S1' pocket. Bioorg Med Chem Lett. 1997 Jan 21;7(2):193-8. | ||||
| REF 21 | Carbamoylphosphonates, a new class of in vivo active matrix metalloproteinase inhibitors. 1. Alkyl- and cycloalkylcarbamoylphosphonic acids. J Med Chem. 2004 May 20;47(11):2826-32. | ||||
| REF 22 | In silico scaffold evaluation and solid phase approach to identify new gelatinase inhibitors. Bioorg Med Chem. 2012 Apr 1;20(7):2323-37. | ||||
| REF 23 | Structure-activity relationships and pharmacokinetic analysis for a series of potent, systemically available biphenylsulfonamide matrix metalloproteinase inhibitors. J Med Chem. 2000 Jan 27;43(2):156-66. | ||||
| REF 24 | Natural products as a gold mine for selective matrix metalloproteinases inhibitors. Bioorg Med Chem. 2012 Jul 1;20(13):4164-71. | ||||
| REF 25 | Synthesis of a series of stromelysin-selective thiadiazole urea matrix metalloproteinase inhibitors. J Med Chem. 1999 May 6;42(9):1525-36. | ||||
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