Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T53748 | Target Info | |||
| Target Name | Plasmodium Enoyl-ACP reductase (Malaria fabI) | ||||
| Synonyms |
fabI; NADH-dependent enoyl-ACP reductase; Enoyl-acyl-carrier protein reductase; Enoyl-acyl carrier reductase; Enoyl-acyl carrier protein reductase; Enoyl-ACP reductase FabI
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| Target Type | Successful Target | ||||
| Gene Name | Malaria fabI | ||||
| Biochemical Class | CH-CH donor oxidoreductase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 44 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
APIGENIN
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Investigative | Compound Info | ||
| Synonyms |
apigenin; 520-36-5; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; Chamomile; Versulin; Spigenin; Apigenol; 4',5,7-Trihydroxyflavone; Apigenine; C.I. Natural Yellow 1; 5,7,4'-Trihydroxyflavone; Pelargidenon 1449; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone; 2-(p-Hydroxyphenyl)-5,7-dihydroxychromone; UCCF 031; NSC 83244; UNII-7V515PI7F6; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one; CCRIS 3789; CHEBI:18388; CHEMBL28; EINECS 208-292-3; 4H-1-Benzopyran-4-one, 5,7-di
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
5-Chloro-2-(4-chloro-2-(pyrrolidin-1-ylmethyl)phenoxy)phenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL205054; BDBM50182371
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-Chloro-2-(4-chloro-2-((naphthalen-1-ylamino)methyl)phenoxy)phenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL207884; BDBM50182373
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
3-[4-(Diethylamino)phenyl]-5-(4-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227982; ZINC1002925; BDBM50211932; STL035140; AKOS001607115; BIM-0041929.P001; ST50148027; AF-399/11786124; 5-(4-methoxybenzylidene)-3-(4-(diethylamino)phenyl)-2-thioxothiazolidin-4-one
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
3-[(4-Tert-butylphenyl)methylsulfanyl]-2-[(6-chloropyridazin-3-yl)amino]phthalazin-3-ium-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL612000; BDBM50370967
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| Activity |
IC50 = 50000 nM
|
[3] | |||
| Compound Name |
5-Chloro-2-(4-chloro-2-(piperidin-1-ylmethyl)phenoxy)phenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL206531; BDBM50182381
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-(2-(Aminomethyl)-4-chlorophenoxy)-5-chlorophenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL377366; BDBM50182389
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-(2-(Aminomethyl)phenoxy)-5-chlorophenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL381983; BDBM50182384
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-(3-Chlorophenylthio)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)quinoline-4-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227191; BDBM50211911; AKOS002109592; MCULE-3097163622; NCGC00319954-01; AB01316336-02; 2-[(3-chlorophenyl)thio]-N-1,2,3,4-tetrahydronaphthalen-1-ylquinoline-4-carboxamide
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| Activity |
IC50 = 50000 nM
|
[3] | |||
| Compound Name |
4-((5Z)-5-{[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)butanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL226156; ZINC1452586; BDBM50211930; AKOS001665974
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| Activity |
IC50 = 50000 nM
|
[3] | |||
| Compound Name |
N-(2-(4-Chloro-2-methoxyphenoxy)benzyl)(4-chlorophenyl)methanamine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL206315; BDBM50182388
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-(2-((4-Benzhydrylpiperazin-1-yl)methyl)-4-chlorophenoxy)-5-chlorophenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL264899; BDBM50182387
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|
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
5-(Anthracen-10-ylmethylene)-3-(4-methoxyphenyl)-2-thioxothiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227930; BDBM50211931; STL427585; ZINC13576460; AKOS000516573; ST50233388; 5-(9-anthrylmethylene)-3-(4-methoxyphenyl)-2-thioxo-1,3-thiazolidin-4-one; (5Z)-5-(anthracen-9-ylmethylidene)-3-(4-methoxyphenyl)-2-thioxo-1,3-thiazolidin-4-one
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
N-(4-Chlorobenzyl)-2-(4-chlorobenzylthio)quinazolin-4-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227243; N-(4-chlorobenzyl)-2-((4-chlorobenzyl)thio)quinazolin-4-amine; N-(4-chlorobenzyl)-2-[(4-chlorobenzyl)thio]quinazolin-4-amine; Oprea1_319961; ZINC2933046; BDBM50211933; AKOS002091122; MCULE-8660053277; SR-01000565365; SR-01000565365-1; BRD-K61308729-001-01-6; F6548-4425
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| Activity |
IC50 = 52000 nM
|
[3] | |||
| Compound Name |
N-(5-Chloro-2-hydroxyphenyl)-5-(4-methoxyphenyl)isoxazole-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL226187; MLS001197773; cid_17252838; HMS2874E07; ZINC3907864; BDBM50211918; AKOS001803056; MCULE-8701882332; SMR000559846; ST50678150; N-(5-chloro-2-hydroxyphenyl)[5-(4-methoxyphenyl)isoxazol-3-yl]carboxamide
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| Activity |
IC50 = 55000 nM
|
[3] | |||
| Compound Name |
N-(5-Chloro-2-methoxyphenyl)-2-(5-chlorothiophen-2-yl)quinoline-4-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227299; ZINC9598063; BDBM50211903; AKOS001498007; MCULE-9204035459; N-(5-chloro-2-methoxyphenyl)-2-(5-chlorothien-2-yl)quinoline-4-carboxamide
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| Activity |
IC50 = 60000 nM
|
[3] | |||
| Compound Name |
2-(5-Chlorothiophen-2-yl)-N-(2-(3,4-dihydroquinolin-1(2H)-yl)ethyl)quinoline-4-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227300; ZINC4788073; BDBM50211895; MCULE-1582371202; 2-(5-chlorothien-2-yl)-N-[2-(3,4-dihydroquinolin-1(2H)-yl)ethyl]quinoline-4-carboxamide
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| Activity |
IC50 = 60000 nM
|
[3] | |||
| Compound Name |
2-(2-(4-Chlorostyryl)-1H-benzo[d]imidazol-5-yl)-4,5,6,7-tetrachloroisoindoline-1,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL438657; BDBM50211898; ZINC28645080; AKOS001574082
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| Activity |
IC50 = 70000 nM
|
[3] | |||
| Compound Name |
N-(5-Chloro-2-hydroxyphenyl)-5-(4-chlorophenyl)isoxazole-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL226052; HMS3437P22; ZINC3907689; BDBM50211896; AKOS001802966; MCULE-6026597356; ST50676762; N-(5-chloro-2-hydroxyphenyl)[5-(4-chlorophenyl)isoxazol-3-yl]carboxamide
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| Activity |
IC50 = 75000 nM
|
[3] | |||
| Compound Name |
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-4-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)benzenesulfonamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL226157; Oprea1_876345; ZINC2950319; BDBM50211886; AKOS002084981; MCULE-9214413939; SR-01000553976; SR-01000553976-1
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| Activity |
IC50 = 90000 nM
|
[3] | |||
| Compound Name |
Methylenebissantin
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933858; BDBM50360385
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| Activity |
IC50 = 91130 nM
|
[4] | |||
| Compound Name |
2-(Dimethylamino)ethyl 6-(5-benzylidene-4-oxo-2-thioxothiazolidin-3-yl)hexanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227535; ZINC4070682; BDBM50211891; AKOS000532155; ST50147122; AF-399/33695010; 2-(dimethylamino)ethyl 6-(5-benzylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)hexanoate; 6-(5-Benzylidene-4-oxo-2-thioxo-thiazolidin-3-yl)-hexanoic acid 2-dimethylamino-; 2-(dimethylamino)ethyl 6-[4-oxo-5-(phenylmethylene)-2-thioxo-1,3-thiazolidin-3 -yl]hexanoate
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
6-(5-(4-Isopropylbenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227593; BDBM50211909; STK809694; ZINC13343101; AKOS002524109; 6-{(5Z)-4-oxo-5-[4-(propan-2-yl)benzylidene]-2-thioxo-1,3-thiazolidin-3-yl}hexanoic acid
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
5-(4-(Dimethylamino)benzylidene)-3-(4-methoxyphenyl)-2-thioxothiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227874; ZINC1236477; BDBM50211922; STK877836; AKOS005068694; (5Z)-5-[4-(dimethylamino)benzylidene]-3-(4-methoxyphenyl)-2-thioxo-1,3-thiazolidin-4-one
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-(2,4-Dichlorophenoxy)-5-(2H-1,2,3,4-tetrazol-5-yl)phenol
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Investigative | Compound Info | ||
| Synonyms |
Triclosan derivative, 5; CHEMBL259734; BDBM25404; 2-(2,4-dichlorophenoxy)-5-(2H-tetrazol-5-yl)phenol
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
3-(3-Chlorophenyl)-5-((5-(4-chlorophenyl)furan-2-yl)methylene)-2-thioxothiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL374387; BDBM50211920
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(5Z)-5-(3-Hydroxybenzylidene)-3-phenyl-2-thioxo-1,3-thiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227929; ZINC1005474; BDBM50211921; STK234839; AKOS000946152; 5-(3-hydroxybenzylidene)-3-phenyl-2-thioxothiazolidin-4-one; 5-(3-hydroxybenzylidene)-3-phenyl-2-thioxo-1,3-thiazolidin-4-one
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
5-(4-Isopropylbenzylidene)-3-(4-methoxyphenyl)-2-thioxothiazolidin-4-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL227873; ZINC1013902; BDBM50211889; STL427564; AKOS005068726; (5Z)-3-(4-methoxyphenyl)-5-[4-(propan-2-yl)benzylidene]-2-thioxo-1,3-thiazolidin-4-one
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Methyl 6-(5-(4-chlorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227536; ZINC4070704; BDBM50211917; STL035321; AKOS002196833; ST50147241; F0207-0514; (Z)-methyl 6-(5-(4-chlorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoate
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
5-((5-(3,4-Dichlorophenyl)furan-2-yl)methylene)-3-methyl-2-thioxothiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL388950; SCHEMBL7859663; ZINC1446610; BDBM50211914; AKOS005129289
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
6-(5-((1H-Indol-3-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL222215; BDBM50158365; 5-(1H-indol-3-ylmethylene)-4-oxo-2-thioxo-3-thiazolidinehexanoic acid; (Z)-6-(5-((1H-indol-3-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoic acid
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| Activity |
IC50 = 100000 nM
|
[3] | |||
| Compound Name |
6-(5-(4-(Benzyloxy)-3-methylbenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL228189; BDBM50211913
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Methyl 6-(5-(4-ethylbenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL390063; BDBM50211929
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
5-(4-Methoxybenzylidene)-3-(4-methoxyphenyl)-2-thioxothiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL390086; BDBM50211936; STK877831; ZINC12625250; AKOS001056630; (5Z)-5-(4-methoxybenzylidene)-3-(4-methoxyphenyl)-2-thioxo-1,3-thiazolidin-4-one
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
3-[5-(2,4-Dichloro-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-propionic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227534; SCHEMBL14788004; ZINC2900363; BDBM50211928; AKOS000523188; ST50147358; AB00088285-01; 2-(dimethylamino)ethyl 3-(5-(2,4-dichlorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoate
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
3-(3-Fluorophenyl)-5-(furan-2-ylmethylene)-2-thioxothiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL228154; ZINC970591; BDBM50211934; STK742281; AKOS005527073; (5Z)-3-(3-fluorophenyl)-5-(furan-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Methyl 6-(5-(3-hydroxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL389850; BDBM50211906
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(5Z)-3-(4-Fluorophenyl)-5-(3-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL390087; BDBM50211916; STL025558; ZINC15015238; AKOS000349742; ST50147898; AG-690/12089016; 5-(3-hydroxybenzylidene)-3-(4-fluorophenyl)-2-thioxothiazolidin-4-one; 3-(4-fluorophenyl)-5-(3-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
5-(3,5-Dichloro-4-hydroxybenzylidene)-3-ethyl-2-thioxothiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227591; BDBM50211925
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(5Z)-5-Benzylidene-3-(4-methoxyphenyl)-2-thioxo-1,3-thiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227820; ZINC1227271; BDBM50211926; STK396875; AKOS000349591; ST50147097; AB00077652-01; 5-benzylidene-3-(4-methoxyphenyl)-2-thioxothiazolidin-4-one; 3-(4-methoxyphenyl)-5-(phenylmethylene)-2-thioxo-1,3-thiazolidin-4-one
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
4-(2,4-Dichlorophenoxy)-3-hydroxybenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL240808; Triclosan derivative, 7; SCHEMBL13236282; BDBM25406; ZINC28869369; 4-(2,4-dichlorophenoxy)-3-hydroxy-benzoic acid
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
3-(3-Chlorophenyl)-5-((5-(3-chlorophenyl)furan-2-yl)methylene)-2-thioxothiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL388951; BDBM50211900; STL427333; ZINC28644998; AKOS025261303
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(5Z)-5-[4-(Diethylamino)-2-hydroxybenzylidene]-3-ethyl-2-thioxo-1,3-thiazolidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL390064; SCHEMBL13236128; ZINC5127792; BDBM50211927; STL427540; AKOS000412158; (Z)-5-(4-(diethylamino)-2-hydroxybenzylidene)-3-ethyl-2-thioxothiazolidin-4-one; 5-(4-(diethylamino)-2-hydroxybenzylidene)-3-ethyl-2-thioxothiazolidin-4-one
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
6-{(5Z)-5-[3-Methoxy-4-(pentyloxy)benzylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}hexanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL389008; ZINC4136154; BDBM50211910; SBB043423; STL331434; AKOS000273906; ST50185941
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Vanillic acid
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|
Investigative | Compound Info | ||
| Synonyms |
4-HYDROXY-3-METHOXYBENZOIC ACID; Acide vanillique; Benzoic acid, 4-hydroxy-3-methoxy-; p-Vanillic acid; 3-Methoxy-4-hydroxybenzoic acid; Vanillate; m-Anisic acid, 4-hydroxy-; Protocatechuic acid, 3-methyl ester; 4-hydroxy-3-methoxy-Benzoic acid; UNII-GM8Q3JM2Y8; 4-Hydroxy-3-methoxybenzoate; NSC 3987; MFCD00002551; NSC 674322; GM8Q3JM2Y8; CHEMBL120568; 4-hydroxy-3-methoxy benzoic acid; NSC674322; VA (VAN); 4-Hydroxy-3-methoxybenzoic acid, 97+%; 4-hydroxy-m-Anisic acid; EINECS 204-466-8; BRN 2208364; Vanillinsaure; VanillicAcid; p-Vanillate; Vanilic acid; AI3-19542; Vanillic Acid,(S); 4-hydroxy-m-Anisate; Vanillic acid (M2); Vanillic acid, 97%; PubChem19485; ACMC-1BPT2; bmse000486; bmse000614; bmse010205; WLN: QVR DQ CO1; 3-Methoxy-4-hydroxybenzoate; SCHEMBL26179; KSC178S8B; MLS000574833; 4-hydroxy-3-methoxy-Benzoate; 4-Hydroxy-3-methoxybenzoicacid; Vanillic acid, >=97%, FG; 4-hydroxy-3methoxy benzoic acid; DTXSID6059522; CTK0H8980; 4-hydroxyl-3-methoxybenzoic acid; NSC3987; 4- hydroxy-3-methoxybenzoic acid; HMS2197E16; Protocatechuic acid 3-methyl ester; ZINC338275; HY-N0708; KS-00000CA7; NSC-3987; STR02334; ANW-17590; BBL011982; BDBM50337364; s5343; SBB008280; STL163472; AKOS000113195; CCG-266343; MCULE-2667517874; MP-2220; NSC-674322; NCGC00247610-01; AC-11841; AK-32998; BP-13246; BR-32998; SC-15609; SMR000156289; ST086485; SY001450; DB-003804; Vanillic acid, purum, >=97.0% (HPLC); AM20050239; CS-0009728; FT-0650155; C06672; Vanillic acid, Vetec(TM) reagent grade, 97%; 198598-EP2277877A1; Q419672; Q-201921; Z1741973874; Vanillic acid, certified reference material, TraceCERT(R); 3E9555E5-85F5-4FCE-A429-5182E959C6A3
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| Activity |
IC50 = 920000 nM
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[4] | |||
| References | Top | ||||
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| REF 1 | Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. J Med Chem. 2006 Jun 1;49(11):3345-53. | ||||
| REF 2 | Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2'-substituted triclosan der... Bioorg Med Chem Lett. 2006 Apr 15;16(8):2163-9. | ||||
| REF 3 | Discovery of a rhodanine class of compounds as inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase. J Med Chem. 2007 May 31;50(11):2665-75. | ||||
| REF 4 | Methylenebissantin: a rare methylene-bridged bisflavonoid from Dodonaea viscosa which inhibits Plasmodium falciparum enoyl-ACP reductase. Bioorg Med Chem Lett. 2012 Jan 1;22(1):610-2. | ||||
| REF 5 | X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalar... J Biol Chem. 2007 Aug 31;282(35):25436-44. | ||||
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