Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T61317 | Target Info | |||
| Target Name | Plasmodium Oxoacyl-[acyl-carrier protein] reductase (Malaria fabG) | ||||
| Synonyms |
3-oxoacyl-acyl-carrier protein reductase
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| Target Type | Clinical trial Target | ||||
| Gene Name | Malaria fabG | ||||
| Biochemical Class | Short-chain dehydrogenases reductase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
CIRSIMARITIN
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Investigative | Compound Info | ||
| Synonyms |
Cirsimaritin; 6601-62-3; Scrophulein; Skrofulein; 4',5-Dihydroxy-6,7-dimethoxyflavone; 7-Methylcapillarisin; cirsimartin; 6,7-Dimethoxyscutellarein; CHEMBL348436; 5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-chromen-4-one; CHEBI:81337; 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-; 6-Methoxygenkwanin; Flavone, 4',5-dihydroxy-6,7-dimethoxy-; AC1Q6AIG; AC1L4MLD; MLS000876998; cid_188323; MEGxp0_000498; SCHEMBL1663486; CTK2F4258; ACon1_000850; DTXSID00216220; PubChem SID: 26725076; MolPort-000-779-119
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| Activity |
IC50 = 70000 nM
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[1] | |||
| Compound Name |
GALANGIN
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Investigative | Compound Info | ||
| Synonyms |
Galangin; 548-83-4; Norizalpinin; 3,5,7-Trihydroxyflavone; 3,5,7-Trihydroxy-2-phenyl-4H-chromen-4-one; 3,5,7-triOH-Flavone; UNII-142FWE6ECS; 3,5,7-Trihydroxy-2-phenyl-4-benzopyrone; 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-phenyl-; EINECS 208-960-4; NSC407229; FLAVONE, 3,5,7-TRIHYDROXY-; NSC 407229; NSC-407229; 4H-Benzopyran-4-one, 3,5,7-trihydroxy-2-phenyl-; BRN 0272179; 142FWE6ECS; 3,5,7-trihydroxy-2-phenylchromen-4-one; CHEBI:5262; CHEMBL309490; VCCRNZQBSJXYJD-UHFFFAOYSA-N; 3,5,7-trihydroxy-2-phenyl-4H-benzopyran-4-one
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| Activity |
IC50 = 100000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. J Med Chem. 2006 Jun 1;49(11):3345-53. | ||||
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