Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T65197 | Target Info | |||
| Target Name | Erythropoietin Receptor (EPOR) | ||||
| Synonyms |
Full-length form; EPO-R
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| Target Type | Successful Target | ||||
| Gene Name | EPOR | ||||
| Biochemical Class | Cytokine receptor | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 5 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(S)-4-[Bis-(4-benzyloxy-benzyl)-amino]-4-{2-[2-(2-{(R)-2-[bis-(4-benzyloxy-benzyl)-amino]-4-carboxy-butyrylamino}-ethoxy)-ethoxy]-ethylcarbamoyl}-butyric acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL387062; BDBM50091845
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| Activity |
IC50 = 75000 nM
|
[1] | |||
| Compound Name |
{Bis-[(E)-3-(3-phenoxy-phenyl)-allyl]-amino}-acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL59107; BDBM50091848; N,N-Bis(3-phenoxy-trans-cinnamyl)glycine
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| Activity |
IC50 = 85000 nM
|
[1] | |||
| Compound Name |
4-((S)-5-[Bis-(4-benzyloxy-benzyl)-amino]-5-{12-[(R)-2-[bis-(4-benzyloxy-benzyl)-amino]-6-(4-carboxy-butyrylamino)-hexanoylamino]-dodecylcarbamoyl}-pentylcarbamoyl)-butyric acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL437982; BDBM50091847
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| Activity |
IC50 = 85000 nM
|
[1] | |||
| Compound Name |
N-((S)-5-[Bis-(4-benzyloxy-benzyl)-amino]-5-{12-[(R)-2-[bis-(4-benzyloxy-benzyl)-amino]-6-(3-carboxy-propionylamino)-hexanoylamino]-dodecylcarbamoyl}-pentyl)-succinamic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL268782; BDBM50091852
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
(S)-2-{Bis-[(E)-3-(3-phenoxy-phenyl)-allyl]-amino}-3-hydroxy-propionic acid methyl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL61574; BDBM50091853; N,N-Bis(3-phenoxy-trans-cinnamyl)-L-serine methyl ester
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| Activity |
IC50 = 145000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis and erythropoietin receptor binding affinities of N,N-disubstituted amino acids. Bioorg Med Chem Lett. 2000 Sep 4;10(17):1995-9. | ||||
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