Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T69091 | Target Info | |||
| Target Name | P2X purinoceptor 1 (P2RX1) | ||||
| Synonyms |
Purinergic receptor 1; P2X1
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| Target Type | Literature-reported Target | ||||
| Gene Name | P2RX1 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Dibenzo[b,f]azepin-5-yl pyrrolidinyl ketone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3103372; Oprea1_069626; Oprea1_338062; HMS1673A03; ZINC271506; BDBM50446069; STK368633; AKOS000573479; MCULE-6476076046; ST50728730; 5H-dibenzo[b,f]azepin-5-yl(pyrrolidin-1-yl)methanone
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| Activity |
IC50 = 68800 nM
|
[1] | |||
| Compound Name |
N-Cyclohexyl-5H-dibenzo[b,f]azepine-5-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3103369; ZINC509938; BDBM50446072; CCG-19269; STL330273; AKOS001647139; MCULE-4989988382; ST51024057; N-cyclohexyldibenzo[b,f]azepin-5-ylcarboxamide; SR-01000477683; SR-01000477683-1
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| Activity |
IC50 = 69600 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Carbamazepine derivatives with P2X4 receptor-blocking activity. Bioorg Med Chem. 2014 Feb 1;22(3):1077-88. | ||||
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