Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T72841 | Target Info | |||
| Target Name | Estrogen-related receptor-alpha (ESRRA) | ||||
| Synonyms |
Nuclear receptor subfamily 3 group B member 1; NR3B1; Estrogen-relatedreceptor, alpha; Estrogen-relatedreceptor alpha; Estrogen-related receptor alpha; Estrogen receptor-like 1; ESRL1; ERRalpha; ERR1; ERR-alpha
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| Target Type | Successful Target | ||||
| Gene Name | ESRRA | ||||
| Biochemical Class | Nuclear hormone receptor | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 5 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(2-Aminophenyl)-[1-(3-phenylmethoxyphenyl)triazol-4-yl]methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381361; BDBM50434085
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-[4-(2-Aminobenzoyl)triazol-1-yl]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381367; BDBM50434079
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
[1-(4-Propan-2-ylphenyl)triazol-4-yl]-[2-(trifluoromethyl)phenyl]methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381475; BDBM50434100
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
3-[4-(2-Aminobenzoyl)triazol-1-yl]benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381366; BDBM50434080
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-[4-(2-Aminobenzoyl)triazol-1-yl]benzonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381365; BDBM50434081
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| References | Top | ||||
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| REF 1 | 1-Phenyl-4-benzoyl-1H-1,2,3-triazoles as orally bioavailable transcriptional function suppressors of estrogen-related receptor alpha. J Med Chem. 2013 Jun 13;56(11):4631-40. | ||||
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