Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T78650 | Target Info | |||
| Target Name | Phospholipid transfer protein (PLTP) | ||||
| Synonyms |
Plasma phospholipid transfer protein; Lipid transfer protein II; Lipid II precursor
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| Target Type | Literature-reported Target | ||||
| Gene Name | PLTP | ||||
| Biochemical Class | Bactericidal permeability increasing protein | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 9 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N-(5-Butyl-4-(4-hydroxyphenyl)-1,3-selenazol-2-yl)acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222814; BDBM50325139
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| Activity |
IC50 = 60000 nM
|
[1] | |||
| Compound Name |
N-[5-Butyl-4-(4-hydroxyphenyl)-1,3-selenazol-2-yl]-4-chlorobenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222815; BDBM50325140; N-(5-butyl-4-(4-hydroxyphenyl)-1,3-selenazol-2-yl)-4-chlorobenzamide
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| Activity |
IC50 = 60000 nM
|
[1] | |||
| Compound Name |
N-(5-Benzyl-4-(4-hydroxyphenyl)-1,3-selenazol-2-yl)hexanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222667; BDBM50325129
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| Activity |
IC50 = 60000 nM
|
[1] | |||
| Compound Name |
4-Chloro-N-[5-ethyl-4-(4-hydroxyphenyl)-1,3-selenazol-2-yl]benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222506; BDBM50325132; 4-chloro-N-(5-ethyl-4-(4-hydroxyphenyl)-1,3-selenazol-2-yl)benzamide
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| Activity |
IC50 = 60000 nM
|
[1] | |||
| Compound Name |
N-[5-Benzyl-4-(4-methoxyphenyl)-1,3-selenazol-2-yl]-3,4-dimethoxybenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222598; BDBM50325127; N-(5-benzyl-4-(4-methoxyphenyl)-1,3-selenazol-2-yl)-3,4-dimethoxybenzamide
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| Activity |
IC50 = 80000 nM
|
[1] | |||
| Compound Name |
N-[5-Butyl-4-(4-methoxyphenyl)-1,3-selenazol-2-yl]-3,4-dimethoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222817; BDBM50325142; N-(5-butyl-4-(4-methoxyphenyl)-1,3-selenazol-2-yl)-3,4-dimethoxybenzamide
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| Activity |
IC50 = 80000 nM
|
[1] | |||
| Compound Name |
N-[5-Benzyl-4-(4-methoxyphenyl)-1,3-selenazol-2-yl]-4-nitrobenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222600; BDBM50325134; N-(5-benzyl-4-(4-methoxyphenyl)-1,3-selenazol-2-yl)-4-nitrobenzamide
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| Activity |
IC50 = 85000 nM
|
[1] | |||
| Compound Name |
N-[5-Ethyl-4-(4-methoxyphenyl)-1,3-selenazol-2-yl]-3,4-dimethoxybenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222505; BDBM50325131; N-(5-ethyl-4-(4-methoxyphenyl)-1,3-selenazol-2-yl)-3,4-dimethoxybenzamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-[5-Butyl-4-(4-methoxyphenyl)-1,3-selenazol-2-yl]-3,4,5-trimethoxybenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222816; BDBM50325141; N-(5-butyl-4-(4-methoxyphenyl)-1,3-selenazol-2-yl)-3,4,5-trimethoxybenzamide
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| Activity |
IC50 = 150000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis of a series of novel 2,4,5-trisubstituted selenazole compounds as potential PLTP inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5123-5. | ||||
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