Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
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| Target ID | T88126 | Target Info | |||
| Target Name | Bacterial Nicotinate-nucleotide adenylyltransferase (Bact nadD) | ||||
| Synonyms |
nadD of Escherichia coli (strain K12); Nicotinate mononucleotide adenylyltransferase of Escherichia coli (strain K12); NaMN adenylyltransferase of Escherichia coli (strain K12); Deamido-NAD(+)Nicotinate-nucleotide adenylyltransferase pyrophosphorylase of Escherichia coli (strain K12); Deamido-NAD(+) pyrophosphorylase of Escherichia coli (strain K12); Deamido-NAD(+) diphosphorylase of Escherichia coli (strain K12)
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| Target Type | Patented-recorded Target | ||||
| Gene Name | Bact nadD | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
3-Amino-N-(3-chlorophenyl)-6-(4-pyridinyl)thieno[2,3-b]pyridine-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
3-amino-N-(3-chlorophenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide; NadD inhibitor 3_17; Oprea1_229015; CHEMBL3666063; SCHEMBL11887597; BDBM81360; KS-00003S1F; ZINC5660022; AKOS001707318; CCG-123016; MCULE-3834866520; SS-0633; SR-01000147967; US8785499, 3_17; SR-01000147967-1
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| Activity |
IC50 = 170000 nM
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[1] | |||
| Compound Name |
NadD inhibitor 15_11
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3666065; BDBM81362; US8785499, 15_11
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| Activity |
IC50 = 191000 nM
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[1] | |||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
3-Amino-N-(2-chloro-4-fluorophenyl)-6-(4-fluorophenyl)thieno[2,3-b]pyridine-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
NadD inhibitor 3_23; CHEMBL3666064; SCHEMBL11887598; BDBM81361; ZINC661654; RSC002818; MCULE-1474642369; US8785499, 3_23
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| Activity |
IC50 > 200000 nM
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[1] | |||
| References | Top | ||||
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| REF 1 | US patent application no. 8785499B2, Targeting NAD biosynthesis in bacterial pathogens | ||||
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