Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T50773 | Target Info | |||
| Target Name | Dipeptidyl-peptidase 7 (DPP7) | ||||
| Synonyms | Quiescent cell proline dipeptidase; QPP; Dipeptidyl peptidase II; Dipeptidyl peptidase 7; Dipeptidyl peptidase 2; Dipeptidyl aminopeptidase II; DPP2; DPP II | ||||
| Target Type | Patented-recorded Target | ||||
| Gene Name | DPP7 | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: (3S)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine | Ligand Info | |||||
| Structure Description | Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A | PDB:3N0T | ||||
| Method | X-ray diffraction | Resolution | 2.45 Å | Mutation | No | [1] |
| PDB Sequence |
DPGFQERFFQ
37 QRLDHFNFER47 FGNKTFPQRF57 LVSDRFWVRG67 EGPIFFYTGN77 EGDVWAFANN 87 SAFVAELAAE97 RGALLVFAEH107 RYYGKSLPFG117 AQSTQRGHTE127 LLTVEQALAD 137 FAELLRALRR147 DLGAQDAPAI157 AFGGSYGGML167 SAYLRMKYPH177 LVAGALAASA 187 PVLAVAGLGD197 SNQFFRDVTA207 DFEGQSPKCT217 QGVREAFRQI227 KDLFLQGAYD 237 TVRWEFGTCQ247 PLSDEKDLTQ257 LFMFARNAFT267 VLAMMDYPYP277 TDFLGPLPAN 287 PVKVGCDRLL297 SEAQRITGLR307 ALAGLVYNAS317 GSEHCYDIYR327 LYHSCADPTG 337 CGTGPDARAW347 DYQACTEINL357 TFASNNVTDM367 FPDLPFTDEL377 RQRYCLDTWG 387 VWPRPDWLLT397 SFWGGDLRAA407 SNIIFSNGNL417 DPWAGGGIRR427 NLSASVIAVT 437 IQGGAHHLDL447 RASHPEDPAS457 VVEARKLEAT467 IIGEWVKAAR477 RE |
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Human dipeptidyl peptidase DPP7 | ||||
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