Binding Site Information of Target
Target General Information | Top | ||||
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Target ID | T61243 | Target Info | |||
Target Name | Metabotropic glutamate receptor 7 (mGluR7) | ||||
Synonyms | mGluR7; GPRC1G | ||||
Target Type | Literature-reported Target | ||||
Gene Name | GRM7 | ||||
Biochemical Class | GPCR glutamate | ||||
UniProt ID |
Drug Binding Sites of Target | Top | |||||
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Ligand Name: [3H]LY341495 | Ligand Info | |||||
Structure Description | Metabotropic glutamate receptor mGluR7 complexed with LY341495 antagonist | PDB:3MQ4 | ||||
Method | X-ray diffraction | Resolution | 2.80 Å | Mutation | Yes | [1] |
PDB Sequence |
HSIRIEGDVT
50 LGGLFPVHAK60 GCGDIKRENG75 IHRLEAMLYA85 LDQINSDPNL95 LPNVTLGARI 105 LDTCSRDTYA115 LEQSLTFVQA125 LIQKDTKPEK149 VVGVIGASGS159 SVSIMVANIL 169 RLFQIPQISY179 ASTAPELSDD189 RRYDFFSRVV199 PPDSFQAQAM209 VDIVKALGWN 219 YVSTLGSYGE232 KGVESFTQIS242 GGLSIAQSVR255 IPQEDFDRII271 KQLLDTAVVI 285 FANDEDIKQI295 LHFLWVGSEG332 AITIQPKRAT342 VEGFDAYFTS352 RTLENNRRNV 362 WFAEYWEENF372 NCKLKCTGQE394 RIGKDSNYEQ404 EGKVQFVIDA414 VYAMAHALHH 424 MNKDLCAVCP438 EMEQAGGKKL448 LKYIRNVNFN458 GSAGTPVMFN468 KNGDAPGRYD 478 IFQYQNPGYR493 LIGQWTDELQ503 LNIEDM
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References | Top | ||||
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REF 1 | mGluR7 complexed with LY341495 |
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