Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T74363 | Target Info | |||
| Target Name | Urokinase plasminogen activator surface receptor (PLAUR) | ||||
| Synonyms | Urokinase-type plasminogen activator receptor; Urokinase plasminogen activator receptor; Monocyte activation antigenMo3; CD87 antigen; CD87 | ||||
| Target Type | Successful Target | ||||
| Gene Name | PLAUR | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: 2-(Acetylamino)-2-Deoxy-a-D-Glucopyranose | Ligand Info | |||||
| Structure Description | Structure of Human Urokinase Plasminogen Activator in Complex with Urokinase Receptor and an anti-upar antibody at 1.9 A | PDB:2FD6 | ||||
| Method | X-ray diffraction | Resolution | 1.90 Å | Mutation | No | [1] |
| PDB Sequence |
SLRCMQCKTN
9 GDCRVEECAL19 GQDLCRTTIV29 RLWEELELVE42 KSCTHSEKTN52 RTLSYRTGLK 62 ITSLTEVVCG72 LDLCNQGNYL93 ECISCGSSDM103 SCERGRHQSL113 QCRSPEEQCL 123 DVVTHWDDRH143 LRGCGYLPGC153 PGSNGFHNND163 TFHFLKCCNT173 TKCNEGPILE 183 LENLPQNGRQ193 CYSCKGNSTH203 GCSSEETFLI213 DCRGPMNQCL223 VATGTHEPKN 233 QSYMVRGCAT243 ASMCQLGDAF256 SMNHIDVSCC266 TKSGCNHPD
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| Ligand Name: 2-Ethoxyethanol | Ligand Info | |||||
| Structure Description | Structure of Human Urokinase Plasminogen Activator in Complex with Urokinase Receptor and an anti-upar antibody at 1.9 A | PDB:2FD6 | ||||
| Method | X-ray diffraction | Resolution | 1.90 Å | Mutation | No | [1] |
| PDB Sequence |
SLRCMQCKTN
9 GDCRVEECAL19 GQDLCRTTIV29 RLWEELELVE42 KSCTHSEKTN52 RTLSYRTGLK 62 ITSLTEVVCG72 LDLCNQGNYL93 ECISCGSSDM103 SCERGRHQSL113 QCRSPEEQCL 123 DVVTHWDDRH143 LRGCGYLPGC153 PGSNGFHNND163 TFHFLKCCNT173 TKCNEGPILE 183 LENLPQNGRQ193 CYSCKGNSTH203 GCSSEETFLI213 DCRGPMNQCL223 VATGTHEPKN 233 QSYMVRGCAT243 ASMCQLGDAF256 SMNHIDVSCC266 TKSGCNHPD
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Structure of human urokinase plasminogen activator in complex with its receptor. Science. 2006 Feb 3;311(5761):656-9. | ||||
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