Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T85328 | Target Info | |||
| Target Name | Protein tyrosine phosphatase IVA 1 (PRL-1) | ||||
| Synonyms | Protein-tyrosine phosphatase of regenerating liver 1; Protein-tyrosine phosphatase 4a1; Protein tyrosine phosphatase type IVA 1; PTPCAAX1; PTP(CAAXI); PRL1 | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | PTP4A1 | ||||
| Biochemical Class | Phosphoric monoester hydrolase | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: 3-(5,6-dimethylisoindol-2-yl)-N-[(E)-furan-2-ylmethylideneamino]benzamide | Ligand Info | |||||
| Structure Description | Crystal Structure of PRL-1 complex with compound analogy 3 | PDB:5BX1 | ||||
| Method | X-ray diffraction | Resolution | 1.90 Å | Mutation | No | [1] |
| PDB Sequence |
APVEVTYKNM
17 RFLITHNPTN27 ATLNKFIEEL37 KKYGVTTIVR47 VCEATYDTTL57 VEKEGIHVLD 67 WPFDDGAPPS77 NQIVDDWLSL87 VKIKFREEPG97 CCIAVHCVAG107 LGRAPVLVAL 117 ALIEGGMKYE127 DAVQFIRQKR137 RGAFNSKQLL147 YLEKYRPKMR157 LRF |
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Crystal Structure of PRL-1 complex with compound analogy 3 | ||||
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