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| Target General Information |
Top |
| Target ID |
T10897 |
Target Info
|
| Target Name |
Acyl-CoA desaturase (SCD) |
| Synonyms |
hSCD1; Stearoyl-coenzyme A (Delta9) desaturase; Stearoyl-CoA desaturase; Membrane-bound 9 desaturase; Fatty acid desaturase; DesA3; Des A3; Delta-9-stearoyl desaturase; Delta-9 desaturase; Delta(9)-desaturase; 9 stearoyl-desaturase |
| Target Type |
Successful Target |
| Gene Name |
SCD |
| Biochemical Class |
Paired donor oxygen oxidoreductase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Acid anhydride hydrolases |
[+] 1 Acid anhydride hydrolases |
+ |
| Interacting Target Name |
Valosin-containing protein p97 (VCP) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Valosin-containing protein; Transitional endoplasmic reticulum ATPase; TER ATPase; 15S Mg(2+)-ATPase p97 subunit |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Co-fractionation |
[2] |
| References |
Top |
| REF 1 |
Ubiquitin-proteasome-dependent degradation of mammalian ER stearoyl-CoA desaturase. J Cell Sci. 2006 Jun 1;119(Pt 11):2342-53.
|
| REF 2 |
Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
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