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| Target General Information |
Top |
| Target ID |
T22212 |
Target Info
|
| Target Name |
Immunoglobulin gamma Fc receptor IIA (FCGR2A) |
| Synonyms |
Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; FcRII-a; Fc-gamma-RIIa; Fc-gamma RII-a; FCGR2A1; FCG2A; CDw32 A; CD32 A |
| Target Type |
Successful Target |
| Gene Name |
FCGR2A |
| Biochemical Class |
Immunoglobulin |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Protein Name |
Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
AGM7; GRB1; IMD36; p85; p85.ALPHA |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Phosphoinositide 3-kinase and p72syk noncovalently associate with the low affinity Fc gamma receptor on human platelets through an immunoreceptor tyrosine-based activation motif. Reconstitution with synthetic phosphopeptides. J Biol Chem. 1996 May 3;271(18):10775-81.
|
| REF 2 |
Influence of tyrosine phosphorylation on protein interaction with FcgammaRIIa. Biochim Biophys Acta. 1997 Jul 24;1357(3):348-58.
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