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| Target General Information |
Top |
| Target ID |
T35640 |
Target Info
|
| Target Name |
Integrin alpha-L (ITGAL) |
| Synonyms |
Lymphocyte Function-associated Antigen-1; Leukocyte function-associated molecule 1 alpha chain; Leukocyte function associated molecule 1, alpha chain; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; LFA-1; CD11a; CD11 antigen-like family member A |
| Target Type |
Successful Target |
| Gene Name |
ITGAL |
| Biochemical Class |
Integrin |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Protein Name |
Sharpin (SHARPIN) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
SIPL1 |
| Evidence Score (E-score) |
5 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| 3 |
Far Western |
[2] |
| 4 |
Protein-peptide |
[1] |
| 5 |
Protein-peptide |
[2] |
| References |
Top |
| REF 1 |
SHARPIN regulates uropod detachment in migrating lymphocytes. Cell Rep. 2013 Nov 14;5(3):619-28.
|
| REF 2 |
Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-B Signaling. PLoS One. 2015 Nov 23;10(11):e0143423.
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