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Target General Information |
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Target ID |
T44991 |
Target Info
|
Target Name |
Vascular cell adhesion protein 1 (VCAM1) |
Synonyms |
Vascular cell adhesion molecule 1; VCAM-1; V-CAM 1; INCAM-100; CD106 antigen; CD106 |
Target Type |
Literature-reported Target |
Gene Name |
VCAM1 |
UniProt ID |
|
Target Interacting Proteins |
Top |
Acid anhydride hydrolases |
[+] 1 Acid anhydride hydrolases |
+ |
Interacting Target Name |
Valosin-containing protein p97 (VCP) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Valosin-containing protein; Transitional endoplasmic reticulum ATPase; TER ATPase; 15S Mg(2+)-ATPase p97 subunit |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[1] |
2 |
Affinity Capture-Western |
[2] |
Other proteins |
[+] 1 Other proteins |
+ |
Interacting Protein Name |
Moesin (MSN) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
HEL70 |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[1] |
2 |
Affinity Capture-Western |
[3] |
3 |
Reconstituted Complex |
[3] |
References |
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REF 1 |
Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Sci Signal. 2009 Sep 8;2(87):ra51.
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REF 2 |
Proteasomal degradation of preemptive quality control (pQC) substrates is mediated by an AIRAPL-p97 complex. Mol Biol Cell. 2015 Nov 1;26(21):3719-27.
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REF 3 |
Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes. J Cell Biol. 2002 Jun 24;157(7):1233-45.
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