Target Interacting Protein Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T45357 | Target Info | |||
| Target Name | B-cell translocation gene 1 protein (BTG1) | ||||
| Synonyms | Protein BTG1 | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | BTG1 | ||||
| UniProt ID | |||||
| Target Interacting Proteins | Top | ||||
|---|---|---|---|---|---|
| Ester hydrolases | [+] 2 Ester hydrolases | + | |||
| Interacting Protein Name | CCR4-NOT transcription complex subunit 7 (CNOT7) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | CAF1; Caf1a; hCAF.1 | ||||
| Evidence Score (E-score) | 5 Experimental Evidences | + | |||
| 1 | Reconstituted Complex | [1] | |||
| 2 | Yeast two hybrid | [1] | |||
| 3 | Yeast two hybrid | [2] | |||
| 4 | Yeast two hybrid | [3] | |||
| 5 | Yeast two hybrid | [4] | |||
| Interacting Protein Name | CCR4-NOT transcription complex subunit 8 (CNOT8) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | CAF1; CALIF; Caf1b; POP2; hCAF1 | ||||
| Evidence Score (E-score) | 4 Experimental Evidences | + | |||
| 1 | Reconstituted Complex | [4] | |||
| 2 | Yeast two hybrid | [5] | |||
| 3 | Yeast two hybrid | [6] | |||
| 4 | Yeast two hybrid | [2] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Human carbon catabolite repressor protein (CCR4)-associative factor 1: cloning, expression and characterization of its interaction with the B-cell translocation protein BTG1. Biochem J. 1998 Dec 1;336 ( Pt 2):471-81. | ||||
| REF 2 | A directed protein interaction network for investigating intracellular signal transduction. Sci Signal. 2011 Sep 6;4(189):rs8. | ||||
| REF 3 | rec-YnH enables simultaneous many-by-many detection of direct protein-protein and protein-RNA interactions. Nat Commun. 2018 Sep 14;9(1):3747. | ||||
| REF 4 | Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1, the human homolog of a component of the yeast CCR4 transcriptional complex: involvement in estrogen receptor alpha signaling pathway. J Biol Chem. 2001 Mar 30;276(13):9640-8. | ||||
| REF 5 | Towards a proteome-scale map of the human protein-protein interaction network. Nature. 2005 Oct 20;437(7062):1173-8. | ||||
| REF 6 | A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226. | ||||
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