Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T46628 Target Info
Target Name Microsomal triglyceride transfer protein (MTTP)
Synonyms Microsomal triglyceride transfer protein large subunit; MTP
Target Type Successful Target
Gene Name MTTP
UniProt ID
MTP_HUMAN 
Target Interacting Proteins  Top
Other proteins [+] 1 Other proteins +
Interacting Target Name Apolipoprotein B-100 (APOB) Clinical trial Target Interacting Protein Info
UniProt ID
APOB_HUMAN 
Synonyms Apolipoprotein B48; Apolipoprotein B-100; Apo B48; Apo B-100; Apo B100
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Yeast two hybrid [2]
References  Top
REF 1 Novel Abetalipoproteinemia Missense Mutation Highlights the Importance of the N-Terminal -Barrel in Microsomal Triglyceride Transfer Protein Function. Circ Cardiovasc Genet. 2015 Oct;8(5):677-87.
REF 2 A common binding site on the microsomal triglyceride transfer protein for apolipoprotein B and protein disulfide isomerase. J Biol Chem. 1999 Jan 29;274(5):3159-64.

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